(Press-News.org) About The Study: In this randomized clinical trial including 103 American Indian patients, a telephone-based strategy of remote initiation and titration for outpatients with heart failure with reduced ejection fraction led to improved rates of guideline-directed medical therapy at 30 days compared with usual care. This low-cost strategy could be expanded to other rural settings where access to care is limited.
Authors: Lauren A. Eberly, M.D., M.P.H., of the Indian Health Service in Gallup, New Mexico, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamainternmed.2024.1523)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
Media advisory: This study is being released to coincide with presentation at the American College of Cardiology’s Annual Scientific Session.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2024.1523?guestAccessKey=bf7cfaa1-998e-4e8d-b030-3ae57fd7aa0e&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=040724
END
Telephone-based guideline-directed medical therapy optimization in Navajo nation
JAMA Internal Medicine
2024-04-07
ELSE PRESS RELEASES FROM THIS DATE:
AACR: Novel immunotherapies show promise for patients with kidney cancer and for solid organ transplant recipients with skin cancer
2024-04-07
ABSTRACTS: CT002, CT003
SAN DIEGO ― Researchers from The University of Texas MD Anderson Cancer Center presented encouraging findings today from two clinical trials in a plenary session highlighting advances in novel immunotherapy approaches at the American Association for Cancer Research (AACR) Annual Meeting 2024. The studies describe the use of chimeric antigen receptor (CAR) T cell therapy in patients with advanced kidney cancer and an oncolytic immunotherapy for patients with skin cancer following organ transplants. Information on all MD Anderson AACR Annual Meeting content can be found at MDAnderson.org/AACR.
Novel allogenic ...
New Phase 1 data from Memorial Sloan Kettering Cancer Center shows an investigational cancer vaccine may elicit lasting immune response in patients with pancreatic cancer
2024-04-07
New data presented today by Memorial Sloan Kettering Cancer Center (MSK) researchers show an experimental approach to treating pancreatic cancer with the messenger RNA (mRNA)-based therapeutic cancer vaccine candidate, autogene cevumeran, continues to show potential to stimulate an immune response that may reduce the risk of the disease returning after surgery. New results from a phase 1 clinical trial show that the cancer vaccine candidate activated immune cells that persisted in the body for up to three years after treatment in certain patients. In addition, a vaccine-induced immune ...
Clinical benefit and regulatory outcomes of cancer drugs receiving accelerated approval
2024-04-07
About The Study: Most cancer drugs granted accelerated approval did not demonstrate benefit in overall survival or quality of life within five years of accelerated approval. Patients should be clearly informed about the cancer drugs that use the accelerated approval pathway and do not end up showing benefits in patient-centered clinical outcomes.
Authors: Aaron S. Kesselheim, M.D., J.D., M.P.H., of Brigham and Women’s Hospital and Harvard Medical School in Boston, is the corresponding author.
To access the embargoed ...
Remote care approach improved therapy adherence and uptake in patients with type 2 diabetes
2024-04-07
KEY TAKEAWAYS
Researchers at Mass General Brigham tested a remote patient education and navigation program with 200 patients who had type 2 diabetes and elevated cardiovascular/kidney risk.
Patients who received education simultaneously with treatment were more likely to begin and adhere to treatment while a period of education prior to therapy initiation was inferior for prescription acceptance and therapy uptake.
The study highlights the importance of “striking while the iron is hot” and the potential for remote, team-based care to bridge ...
Trial to improve management of common heart rhythm disorder enrols first patient
2024-04-07
Sophia Antipolis, France – 7 April 2024: The first EU-wide trial aiming to improve the care of elderly atrial fibrillation patients with additional chronic health conditions has enrolled its first patient. The EU-funded EHRA-PATHS study is coordinated by the European Society of Cardiology (ESC) and the European Heart Rhythm Association (EHRA) of the ESC.
Atrial fibrillation is the most common heart rhythm disorder, affecting more than 40 million individuals worldwide.1 The likelihood of developing the condition increases with age and the number of other conditions such as high blood pressure, ...
Electronic sock detects unhealthy walking style
2024-04-07
Berlin, Germany – 7 April 2024: An electronic sock that detects an unhealthy walking style linked with diabetes and poor circulation shows promise for preventing foot ulcers and amputation. The novel research is set to benefit the many patients with diabetes who have clogged arteries in the legs and is presented for the first time at EHRA 2024, a scientific congress of the European Society of Cardiology (ESC).1
Study author Dr. Ki Hong Lee of Chonnam National University Hospital, Gwangju, Republic of Korea said: “Diabetes can affect the way people walk, also known as their gait. Patients with diabetes tend to put pressure ...
Stopping aspirin one month after coronary stenting procedures significantly reduces bleeding complications in heart attack patients
2024-04-07
Withdrawing aspirin one month after percutaneous coronary intervention (PCI) in high-risk heart patients and keeping them on ticagrelor alone safely improves outcomes and reduces major bleeding by more than half when compared to patients taking aspirin and ticagrelor combined (also known as dual antiplatelet therapy or DAPT), which is the current standard of care.
These are the results from the ULTIMATE-DAPT study announced during a late-breaking trial presentation at the American College of Cardiology Scientific ...
Short-term incentives for exercise can lead to sustained increases in activity
2024-04-07
Short-term incentives for exercise can lead to sustained increases in activity
NIH-supported study shows certain perks can spur long-term behavior change in adults with cardiovascular disease risks
Adults with heart disease risks who received daily reminders or incentives to become more active increased their daily steps by more than 1,500 after a year, and many were still sticking with their new habit six months later, according to a study supported by the National Institutes of Health that published in Circulation. ...
Successful “first in human” clinical trial of pioneering guidance for heart bypass surgery
2024-04-07
A new approach to the guidance, planning and conduct of heart bypass surgery has been successfully tested on patients for the first time in a clinical trial coordinated by a research team at University of Galway.
The FAST TRACK CABG study, overseen by the University’s CORRIB Research Centre for Advanced Imaging and Core Lab, has seen heart surgeons plan and carry out coronary artery bypass grafting (CABG), based solely on non-invasive cardiac-CT scan images, with HeartFlow’s AI-powered blood flow analysis of the patient’s coronary arteries.
The research was published today in the European Heart Journal and is available at https://academic.oup.com/eurheartj/article-lookup/doi/10.1093/eurheartj/ehae199
The ...
Influenza vaccine immune response in patients with high-risk cardiovascular disease
2024-04-07
About The Study: High-dose influenza vaccine elicited a more robust humoral response in patients with heart failure or prior myocardial infarction enrolled in the INVESTED randomized clinical trial, with no association between seroconversion status and the risk for cardiopulmonary hospitalizations or all-cause mortality. Vaccination to prevent influenza remains critical in high-risk populations.
Authors: Scott D. Solomon, M.D., of Brigham and Women’s Hospital and Harvard Medical ...
LAST 30 PRESS RELEASES:
Shedding light on materials in the physical, biological sciences
Study finds emotional tweets by politicians don’t always win followers and can backfire with diverse audiences
Paul “Bear” Bryant Awards announce 2025 Coach of the Year Award watch list
$3 million National Institute on Aging grant will provide much-needed support to underserved dementia caregivers
Study links obesity-driven fatty acids to breast cancer, warns against high-fat diets like keto
Did lead limit brain and language development in Neanderthals and other extinct hominids?
New study reveals alarming mental health and substance use disparities among LGBTQ+ youth
U.K. food insecurity is associated with mental health conditions
At least eight bat species commute or forage over pig farms in Northern Italy
Ancient teeth reveal mammalian responses to climate change in Southeast Asia
Targeting young adults beginning university may be especially effective for encouraging pro-environmental behaviors
This robotic skin allows tiny robots to navigate complex, fragile environments
‘Metabots’ shapeshift from flat sheets into hundreds of structures
Starting university boosts recycling and greener travel, a University of Bath study finds
How cilia choreograph their “Mexican wave”, enabling marine creatures to swim
Why women's brains face higher risk: scientists pinpoint X-chromosome gene behind MS and Alzheimer's
Ancient lead exposure shaped evolution of human brain
How the uplift of East Africa shaped its ecosystems: Climate model simulations reveal Miocene landscape transformation
Human Organ Chip technology sets stage for pan-influenza A CRISPR RNA therapies
Research alert: Bacterial chatter slows wound healing
American Society of Anesthesiologists names Patrick Giam, M.D., FASA, new president
High-entropy alloy nanozyme ROS biocatalyst treating tendinopathy via up-regulation of PGAM5/FUNDC1/GPX4 pathway
SwRI’s Dr. Pablo Bueno named AIAA Associate Fellow
Astronomers detect radio signals from a black hole tearing apart a star – outside a galactic center
Locking carbon in trees and soils could help ‘stabilize climate for centuries’ – but only if combined with underground storage
New research shows a tiny, regenerative worm could change our understanding of healing
Australia’s rainforests first to switch from carbon sink to source
First-trimester mRNA COVID-19 vaccination and risk of major congenital anomalies
Glucose-lowering medication classes and cardiovascular outcomes in patients with type 2 diabetes
Rising seas and sinking cities signal a coastal crisis in China
[Press-News.org] Telephone-based guideline-directed medical therapy optimization in Navajo nationJAMA Internal Medicine