(Press-News.org) About The Study: In critically ill sepsis patients, treatment with intravenous acetaminophen for 5 days was safe but did not improve the primary end point of days alive and free of any organ support (dialysis, assisted ventilation, and vasopressors) to day 28 compared with placebo.
Corresponding Author: To contact the corresponding author, Lorraine B. Ware, M.D., email Lorraine.ware@vumc.org.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2024.8772)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
Media advisory: This study is being presented at the American Thoracic Society 2024 International Conference.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.8772?guestAccessKey=1b8c1ae9-3edc-4366-be12-3cf2610d148d&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051924
END
Acetaminophen for prevention and treatment of organ dysfunction in critically ill patients with sepsis
JAMA
2024-05-19
ELSE PRESS RELEASES FROM THIS DATE:
Measuring lung function more accurately and more equitably
2024-05-19
Removing race from equations that estimate lung function will shift the categorization of disease severity across patient populations, moving more Black individuals into an advanced disease category, according to new research led by scientists at Harvard Medical School. At the same time, more white and Hispanic people would be reclassified as having less advanced illness.
The findings, the research team said, suggest that adjusting lung function tests to include race — as has been the case historically — likely normalized worse lung function and downplayed disease severity among Black people.
The work, to be published May 19 in the New England Journal ...
Study reports ‘excellent’ outcomes for patients receiving optimized treatment for atrial fibrillation
2024-05-18
Atrial fibrillation (AF) is the most common form of arrythmia or irregular heartbeat worldwide, impacting millions of people in the U.S. alone. In a new study published in Heart Rhythm, researchers from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, analyzed real-world clinical data to measure the impact of evidence-based best-practices on patient outcomes for the most common AF procedure: radiofrequency (RF)-based ablation. One year after the procedure, 81.6 percent ...
Modular Communicative Leadless ICD is safe and exceeds performance expectations
2024-05-18
Wireless implantable cardioverter-defibrillators (ICDs) eliminate the lead-related complications that come with a wired ICD, but they are unsuitable for patients with ventricular tachycardia, when the heart beats too quickly, or bradycardia, when the resting heart rate is seen as low. Research led by Amsterdam UMC, that is published today in the New England Journal of Medicine, shows that the first wireless modular system suitable for these patient groups is safe and exceeds performance expectations. Opening the door for a wider ...
Patients seen by female gastroenterologists have significantly less health care utilization than patients seen by male providers
2024-05-18
WASHINGTON, DC (May 18, 2024) — Patients seen by a female gastroenterologist for an initial consultation are less likely to use medical care in the emergency department, hospital or primary care office for two years after their visit when compared to patients initially seen by male gastroenterologists, according to a study to be presented at Digestive Disease Week® (DDW) 2024.
“If there really is something different about the way female and male gastroenterologists provide care that impacts patient outcomes, it will be important to share these learnings broadly among health care providers ...
Iso-propagation vortices: optical multiplexing for unprecedented information capacity
2024-05-17
The future of optical communications just got brighter. In a groundbreaking development reported in Advanced Photonics, researchers from Nanjing University have introduced iso-propagation vortices (IPVs), a novel concept that offers a solution to a long-standing challenge faced by scientists and engineers: how to increase information processing capacity while overcoming the limitations of traditional vortex beams.
Challenge: divergence and beam size
Multiplexing of optical degrees of freedom, such as polarization and wavelength, has been a staple in enhancing communication capacity. ...
Ukraine blackouts caused by malware attacks warn against evolving cybersecurity threats to the physical world
2024-05-17
On a cold winter night in 2016, Ukrainians experienced the first-ever known blackout caused by malicious code (malware) designed to autonomously attack the power grid. One-fifth of Kyiv’s citizens were plunged into darkness as attackers used malware to target the capital city’s power grid. Six years later, in the early months of the ongoing Russia-Ukraine war, a second attack attempted to combine kinetic and cyber attacks to take down Ukraine’s power grid.
Malware attacks against physical ...
How memories crystallize over time
2024-05-17
“Practice makes perfect” is no mere cliché, according to a new study from researchers at The Rockefeller University and UCLA. Instead, it’s the recipe for mastering a task, because repeating an activity over and over solidifies neural pathways in your brain.
As they describe in Nature, the scientists used a cutting-edge technology developed by Rockefeller’s Alipasha Vaziri to simultaneously observe 73,000 cortical neurons in mice as the animals learned and repeated a given task over two weeks. The study revealed that memory representations transform from unstable to solid in ...
Gilbert Family Foundation invests $21 million to launch new research initiative focused on developing advanced disease models to accelerate cure for neurofibromatosis
2024-05-17
New initiative, launched on World NF Awareness Day, focuses on developing improved models to understand neurofibromatosis type 1 (NF1) with the goal of rapidly testing new treatments.
18 grants will be provided to leading medical research institutions in the United States and Europe.
The Next-Generation NF1 Models Initiative is the Foundation’s fourth research initiative focused on accelerating a cure for neurofibromatosis.
DETROIT, May 17, 2024 – Gilbert Family Foundation, a private foundation established by Dan and Jennifer Gilbert to accelerate a cure for ...
Multiple onychopapillomas and BAP1 tumor predisposition syndrome
2024-05-17
About The Study: This study found that BRCA1-associated protein (BAP1) tumor predisposition syndrome was associated with a high rate of nail abnormalities consistent with onychopapillomas (a benign tumor of the nail) in adult carriers of the disease. Findings suggest that this novel cutaneous sign may facilitate detection of the syndrome in family members who are at risk and patients with cancers associated with BAP1 given that multiple onychopapillomas are uncommon in the general population and may be a distinct clue to the presence of a pathogenic germline variant in the BAP1 gene.
Corresponding Authors: To contact the corresponding authors, ...
Researchers confirm scale matters in determining vulnerability of freshwater fish to climate changes
2024-05-17
The silver chub isn’t considered sensitive to climate change on a national scale, but context matters. For example, if climate change sensitivity is evaluated in only one region of the United States, the freshwater fish appears quite a bit more susceptible.
“Relative to other species we looked at in the gulf region of the U.S., the silver chub occupied a pretty small geographic area,” said Samuel Silknetter, a Ph.D. student in biological sciences. “If we didn’t look at the climate sensitivity across multiple ...
LAST 30 PRESS RELEASES:
Focal volume optics for composite structuring in transparent solids
Novel mix-charged nanofiltration membrane developed for high-salinity wastewater treatment
Fishy business: Male medaka mating limits revealed
Morning coffee may protect the heart better than all-day coffee drinking
For many low-income single moms, government aid serves as their paid family leave, study shows
Tumor-secreted protein may hold the key to better treatments for deadly brain tumor, study finds
Ready to quit vaping in the new year? A new study uncovers the best ways
Regular physical activity before cancer diagnosis may lower progression and death risks
Basking too long in a sauna without adequate hydration may risk heat stroke, doctors warn
DNA adds new chapter to Indonesia’s layered human history
Many children and young people with diagnosable mental health disorders are not receiving timely help, says new research
Dinosaurs roamed the northern hemisphere millions of years earlier than previously thought, according to new analysis of the oldest North American fossils
Breakthrough Durham University research offers new insights into quenching electrical waves in the heart
SLAC will play a key role in DOE’s new research centers for advancing next-generation microelectronics
Market researchers and online advertisers, are A-B tests leading you astray? A new study says they could be
Research alert: Ketamine use on the rise in U.S. adults; new trends emerge
Crop switching for climate change in China
Cell-based therapy improves outcomes in a pig model of heart attacks
Researchers have a better understanding of how our cells dispose of waste while developing ways to control it
Earth’s air war: Explaining the delayed rise of plants, animals on land
More than half of college students report alcohol-related harms from others
Smart food drying techniques with AI enhance product quality and efficiency
Typical cost of developing new pharmaceuticals is skewed by high-cost outliers
Predicting the progression of autoimmune disease with AI
Unlocking Romance: UCLA offers dating program for autistic adults
Research Spotlight: Researchers reveal the influences behind timing of sleep spindle production
New research reveals groundwater pathways across continent
Students and faculty to join research teams this spring at Department of Energy National Laboratories and a fusion facility
SETI Forward recognizes tomorrow’s cosmic pioneers
Top mental health research achievements of 2024 from the Brain & Behavior Research Foundation
[Press-News.org] Acetaminophen for prevention and treatment of organ dysfunction in critically ill patients with sepsisJAMA