Substantia nigra pathology, contact sports play, and parkinsonism in chronic traumatic encephalopathy

JAMA Neurology

2024-07-15

(Press-News.org) About The Study: In this cross-sectional study of contact sports athletes with chronic traumatic encephalopathy (CTE), years of contact sports participation were associated with substantia nigra tau pathology and neuronal loss, and these pathologies were associated with parkinsonism. Repetitive head impacts may incite neuropathologic processes that lead to symptoms of parkinsonism in individuals with CTE.

Corresponding Authors: To contact the corresponding authors, email Ann C. McKee, M.D. (amckee@bu.edu) and Thor D. Stein, M.D., Ph.D. (tdstein@bu.edu).

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaneurol.2024.2166)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Substantia nigra pathology, contact sports play, and parkinsonism in chronic traumatic encephalopathy

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