(Press-News.org)
Insilico Medicine (“Insilico”), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today hosts Insilico Medicine Generative AI Action (IMGAIA) webinar. The webinar featured opening remarks by Alex Zhavoronkov, PhD, Founder and CEO of Insilico Medicine. During the virtual event, Alex Aliper, PhD, co-founder and president of Insilico Medicine, announced the company’s sustainability initiative. Following this, the session on product launches and updates was delivered by key AI project leaders.
"Guided by the goal to accelerate scientific research and utilize the power of AI to the most, we announce the generative AI tools today," says Petrina Kamya, PhD, Global Head of Al Platforms and Vice President of Insilico Medicine. "These advancements not only underline our commitment to pioneering scientific breakthroughs but also reflect our dedication to achieving them responsibly, ensuring a healthier and more sustainable future."
Focusing on the challenges posed by data limitations, complex biological processes and tedious document tasks, Insilico presents three novel applications under Pharma.AI, the AI drug discovery platform, namely, Biology42: PandaOmics Box, Precious-3 GPT, and Science42: DORA.
Biology42: PandaOmics Box, an industry-first AI-powered converged research solution currently commercially available in certain regions, integrates PandaOmics, Insilico’s generative AI-driven biological analysis engine, extensive scientific databases, and advanced hardware systems with state-of-the-art computational power and chip-level confidential computing for secure, offline, on-premise deployments.
Precious-3 GPT, an open-source transformer-based large language model (LLM) engine, supports multi-modal, multi-omics, and multi-species biomedical research through virtual data generation. Supported by >2MM omics observations, as well as PubMed text and knowledge graphs, Precious-3 GPT understands basic aging processes in multiple species, thus performing novel protein target discovery, and aging and disease treatments identification.
Science42: DORA, an intelligence research and writing assistant with a free trial expected in late 2024, integrates multiple AI agents that leverage LLMs and is designed to streamline the process of drafting academic papers and other scientific documents including grant and patent applications, internal research summaries, IND applications, etc. It helps accelerate the publication process with proper referencing through engineered prompts, proprietary databases, and pre-designed content generation workflows.
"With IMGAIA, we aim to set industry benchmarks for generative AI in some of the most important areas of sustainability by comprehensive evaluation of generative models in the context of parameters and benchmarks that are required for industrialization of practical sustainability solutions," says Alex Zhavoronkov, PhD, founder and CEO of Insilico Medicine.
Founded in 2014, Insilico Medicine is a pioneer in using generative AI for drug discovery and development. Insilico first described the concept of using generative AI for the design of novel molecules in a peer-reviewed journal in 2016, which laid the foundation for the commercially available Pharma.AI platform spanning across biology, chemistry and clinical development. Powered by Pharma.AI, Insilico has nominated 18 preclinical candidates in its comprehensive portfolio of over 30 assets since 2021, and has received IND approval for 7 molecules. Recently, the company published a paper in Nature Biotechnology presenting the entire R&D journey of its lead drug pipeline, INS018_055, from AI algorithms to Phase II clinical trials.
About Insilico Medicine
Insilico Medicine, a global clinical stage biotechnology company powered by generative AI, is connecting biology, chemistry and clinical trials analysis using next-generation AI systems. The company has developed AI platforms that utilize deep generative models, reinforcement learning, transformers and other modern machine learning techniques for novel target discovery and the generation of novel molecular structures with desired properties. Insilico Medicine is developing breakthrough solutions to discover and develop innovative drugs for cancer, fibrosis, immunity, central nervous system diseases, infectious diseases, autoimmune diseases, and aging-related diseases.
www.insilico.com
END
KINGSTON, R.I. – July 22, 2024 – A team of researchers at the University of Rhode Island and Nova Southeastern University in Florida have been tracking a 26-foot endangered whale shark – named “Rio Lady” – with a satellite transmitter for more than four years – a record for whale sharks and one of the longest tracking endeavors for any species of shark.
Whale sharks, which live from 80 to 130 years, are the world’s largest fish and third largest creature in the ocean – behind blue and fin whales. The size of a small school bus, they inhabit tropical oceans and ...
(WASHINGTON, July 24, 2024) – In patients with diffuse large B-cell non-Hodgkin lymphoma (DLBCL), the two hallmark post-chimeric antigen receptor (CAR)-T therapy toxicities are extremely rare after two weeks, supporting a shorter, more flexible toxicity monitoring period, according to a study published in Blood Advances.
Currently, three CAR T-cell therapies — axicabtagene ciloleucel (axi-cel), tisagenlecleucel (tisa-cel), and lisocabtagene maraleucel (liso-cel) — are approved for treating DLBCL, a cancer that affects the white blood cells responsible for producing antibodies. However, patients receiving these therapies are ...
Information like forest canopy height can be useful in assessing the health of a forest, but current measuring methods are not always feasible for large geographic regions or adaptable to diverse forest types. Monitoring from space can be a solution.
Forests function as more than a place for a quiet retreat: trees intake and absorb carbon dioxide (a major greenhouse gas), a process also known as carbon sequestration, and are essential parts of water regulation, habitat provision, and support much of the world’s terrestrial biodiversity. Quantifying forest structure parameters, ...
All around the world, scientists are striving towards next-generation energy technologies that can help us move away from fossil fuels. Using hydrogen as an energy carrier and clean energy source is perhaps one of the most promising solutions on the horizon. However, there is a major challenge to overcome before hydrogen economies become a reality: hydrogen gas is remarkably difficult to store and transport safely, which severely limits its applicability across many fields.
Against this backdrop, a research team from Tokyo Institute of Technology, Japan, and Tokyo University of Science, Japan has been working hard to reach an alternative solution to the hydrogen storage problem. Led by Associate ...
Exercise is one of the best ways to reduce your risk of heart disease or having a second cardiovascular event, such as a heart attack or stroke.
As more people use wearable technology, such as smartwatches, health care researchers continue to explore whether it can successfully promote physical activity.
That includes customized messages designed to encourage individual patients to be more active in their current location, like walking outside when the weather is nice.
In such a study led by the University of Michigan ...
DALLAS, July 24, 2024 — In this era of machine learning and artificial intelligence, harnessing large-scale neuroimaging can facilitate new discoveries in neuroscience research.[1]
To that end, the American Heart Association, celebrating 100 years of lifesaving service in 2024, has awarded a two-year, $460,000 grant to a consortium of three academic medical centers to work collaboratively and share de-identified imaging data from individuals enrolled in its Get With The Guidelines® – Stroke registry.
A team at Yale University will ...
Glenview, Illinois – The American College of Chest Physicians® (CHEST) recently released a new clinical guideline on central airway obstruction (CAO). Published in the journal CHEST®, the guideline contains 12 evidence-based recommendations to guide the management of both malignant and nonmalignant CAO.
“Central airway obstruction is associated with a poor prognosis, and the management of CAO is highly variable dependent on the provider expertise and local resources. By releasing this guideline, the panel hopes to standardize the definition ...
PULLMAN, Wash. – Marriage equality appears to have a major economic benefit for countries. Washington State University researchers found that European countries that recognized same-sex marriages kept more of their highly skilled workers from emigrating to the U.S.
The researchers analyzed 20 years of data on HB1 visas, which are reserved for immigrants to the U.S. with advanced degrees and specialized skills. From 2000-2019, a total of 13 European Union countries legalized same-sex marriage—and ...
DURHAM, NC – Reforestation in low- and middle-income countries can remove up to 10 times more carbon dioxide from the atmosphere at lower cost than previously estimated, making this a potentially more important option to fight climate change, according to a study in Nature Climate Change.
Reforestation regrows trees on degraded lands where human activities removed original forests. Most current reforestation programs focus on tree planting alone, but the study estimates that nearly half of all suitable reforestation locations would be more effective at sequestering carbon if forests were allowed to grow back ...
WASHINGTON (July 24, 2024)--America's demand for products delivered to the doorstep has led to a dramatic increase in e-commerce and the warehousing industry.
A first-of-a-kind study now shows that people living in communities located next to these large warehouses are exposed to 20% more of a traffic-related air pollutant that can lead to asthma and other life-threatening health conditions.
“Increased truck traffic to and from these recently built large warehouses means people living downwind are inhaling an increased amount of harmful nitrogen dioxide pollution,” said Gaige Kerr, lead author of the study and an assistant research ...
