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Novel human lung organoids can form lifelike models for tuberculosis infection, and might be used to test efficacy of anti-TB drugs

2024-07-25
(Press-News.org) Novel human lung organoids can form lifelike models for tuberculosis infection, and might be used to test efficacy of anti-TB drugs.

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Article URL: http://journals.plos.org/plospathogens/article?id=10.1371/journal. ppat.1012295

Article Title: Advances in an In Vitro Tuberculosis Infection Model Using Human Lung Organoids for Host-Directed Therapies

Author Countries: Republic of Korea

Funding: This research was supported by the Korea National Institutes of Health (NIH) (No. 2021-ER2001-00) awarded to E.M.K., the Korea Institute of Toxicology, Republic of Korea (No. 1711195891) awarded to E.M.K., the Korea Environment Industry & Technology Institute (KEITI) through Technology Development Project for Safety Management of Household Chemical Products, funded by Korea Ministry of Environment (MOE) (RS-2022-KE002021) awarded to E.M.K., the Seoul Women’s University (2024-0049) awarded to E.M.K., and the National Research Foundation of Korea (NRF) grant funded by the Korea Government (MSIT) (No. 2022R1C1C2011153) awarded to J.A.C. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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[Press-News.org] Novel human lung organoids can form lifelike models for tuberculosis infection, and might be used to test efficacy of anti-TB drugs