(Press-News.org)
Cancer is a complex, multifactorial disease with a substantial global burden. Recent years have seen a surge in research focusing on preventive measures, particularly through diet and supplements. The role of nutrition in cancer incidence and prevention is widely recognized, though the specifics of these relationships remain under investigation. This review expands on the findings of Anandu Chandra Khanashyam et al., exploring the nuanced links between diet, supplements, and cancer prevention.
The significance of diet and supplements in cancer prevention is well-documented, with nutrition being a key factor in cancer incidence. Epidemiological research highlights the complex interactions between dietary factors and cancer risk, yet inconsistencies persist, limiting firm conclusions. Factors such as obesity, high-calorie foods, sugary beverages, and processed meats are known to increase cancer risk. Conversely, diets rich in whole grains, vegetables, and fruits are believed to reduce this risk. Obesity is linked to 14% of cancer deaths in men and 20% in women, with specific dietary factors like alcohol, red meats, and aflatoxins being associated with various cancers.
Evidence Linking Diet and Cancer
Historical and contemporary research underscores the role of diet in cancer development. The physician Galen in 168 BC first suggested diet's involvement in cancer growth. Modern epidemiological studies have consistently shown correlations between specific foods and cancer risk. Factors like the amount, timing, and duration of exposure to bioactive food components influence cellular responses and cancer development. It is now understood that the effects are likely due to multiple carcinogenic pathways acting in concert rather than individual compounds.
Dietary Patterns and Cancer Risk
Shifting from a nutrient-centric approach to examining overall dietary patterns offers a more comprehensive understanding of diet's impact on cancer risk. Healthy dietary patterns, characterized by high intake of fruits, vegetables, and whole grains, are associated with a lower risk of cancers, particularly colon and breast cancer. Processed and red meats, which contain carcinogenic compounds formed during high-temperature cooking, are linked to gastrointestinal cancers. However, the evidence remains complex and sometimes contradictory.
Dietary Supplements in Cancer Prevention
While certain micronutrients and antioxidants, such as vitamins B12, D, C, selenium, folic acid, and carotenoids, have shown potential in cancer prevention, their indiscriminate use can be harmful. Well-nourished individuals might not benefit from additional supplements, and excessive intake could increase cancer risk. Phytochemicals and plant extracts, like polyphenols found in fruits, vegetables, and beverages, are promising due to their anti-carcinogenic properties. These compounds can alter molecular processes of metastasis and suppress carcinogenesis initiation.
Phytochemicals and Plant Extracts
Polyphenols, a diverse group of plant constituents, play a significant role in cancer prevention. They are categorized into flavonoids, phenolic acids, lignans, stilbenes, and other polyphenols, with the majority found in fruits, vegetables, and nuts. These compounds exhibit protective effects against various cancers. Probiotics, another functional food group, modify gut microbiota, neutralize carcinogens, and enhance gut barrier function, thus reducing tumor growth and metastasis.
Conclusions
Lifestyle and dietary habits significantly influence cancer risk. Adopting a balanced diet rich in fruits, vegetables, whole grains, and legumes can lower cancer risk. Antioxidants in these foods help repair cells and reduce inflammation, counteracting cancer cell mechanisms. While epidemiological and clinical research has advanced our understanding of diet and cancer prevention, further studies are necessary to clarify these relationships. Caution is advised against excessive supplement use, and dietary modifications should be part of a holistic approach to cancer prevention. There is no conclusive evidence favoring a specific diet, but general healthy dietary patterns positively impact cancer prevention.
In summary, diet and dietary supplements hold promise in cancer prevention, but their role must be understood within the broader context of overall lifestyle and dietary patterns. Continued research is essential to establish effective dietary strategies for cancer prevention.
Full text
https://www.xiahepublishing.com/2835-3315/CSP-2023-00001
The study was recently published in the Cancer Screening and Prevention.
Cancer Screening and Prevention (CSP) publishes high-quality research and review articles related to cancer screening and prevention. It aims to provide a platform for studies that develop innovative and creative strategies and precise models for screening, early detection, and prevention of various cancers. Studies on the integration of precision cancer prevention multiomics where cancer screening, early detection and prevention regimens can precisely reflect the risk of cancer from dissected genomic and environmental parameters are particularly welcome.
Follow us on X: @xiahepublishing
Follow us on LinkedIn: Xia & He Publishing Inc.
END
Z-alkenes are organic compounds with a double bond between two carbon atoms and two substituents attached to the carbon atoms on the same side of the double bond. They are ubiquitous structural components of organic compounds in chemistry and biology. It is well known that many of the Z-alkenes cannot be prepared through conventional methods involving thermodynamic methods while photoisomerization can offer good yields. Photoisomerization is a process in which the structural arrangement of an isomer of a molecule is changed to another isomer by absorption of light. The photoisomerization of E-alkenes to produce Z-alkenes ...
CHAMPAIGN, Ill. — Many studies have focused on falls among people who are ambulatory and have conditions like multiple sclerosis or Parkinson’s disease, but research to address falls among those who rely on wheelchairs or motorized scooters is rare, scientists report in a new study. The researchers found that full-time wheelchair or motorized-scooter users also experience falls and fall-related injuries, and many live with the fear of falling again.
The findings are detailed in the journal Disability and Rehabilitation.
According to the U.S. Census Bureau, 5.5 million Americans ...
North Sea oil and gas extraction can cause pollution to spike by more than 10,000% within half a kilometre around off-shore sites, a study has found for the first time.
The University of Essex, Natural History Museum and Centre for Environment, Fisheries and Aquaculture Science (CEFAS) research has uncovered the true impact on Britain’s seabed life - with the number of species plummeting nearly 30% near platforms.
The findings, published in Science of The Total Environment, come in the face of continued global fossil fuel exploration.
The study discovered pollutants like hydrocarbons were up to 10,613% higher within 500m ...
PULLMAN, Wash. – Companies may unintentionally hurt their sales by including the words “artificial intelligence” when describing their offerings that use the technology, according to a study led by Washington State University researchers.
In the study, published in the Journal of Hospitality Marketing & Management, researchers conducted experimental surveys with more than 1,000 adults in the U.S. to evaluate the relationship between AI disclosure and consumer behavior.
The findings consistently showed products described as using artificial intelligence were less popular, according to Mesut Cicek, clinical assistant professor of marketing and lead author ...
To control the climate crisis, we must tackle methane emissions now. Methane has contributed about half the global warming we’ve experienced so far, and emissions are climbing rapidly. An international team of climate researchers writing in Frontiers in Science set out three imperatives to cut methane emissions and share a new tool to help us find the most cost-effective ways of doing so.
“The world has been rightly focused on carbon dioxide, which is the largest driver of climate change to date,” said Professor ...
Bacteria produce materials that are of interest to humans, such as cellulose, silk and minerals. The advantage of producing bacteria in this way is that it is sustainable, takes place at room temperature and in water. A disadvantage is that the process takes time and gives rise to quantities too small to be of industrial use.
Consequently, researchers have for some time been trying to turn microorganisms into living mini-factories that can produce larger quantities of a desired product more quickly. This requires either targeted intervention in the genome or the cultivation of the most suitable bacterial ...
Researchers in Korea have united to tackle the challenges in the commercialization of all-solid-state batteries. Dr. Yoon-Cheol Ha from the Next Generation Battery Research Center of KERI collaborated with a team led by professor Byung Gon Kim of Department of Applied Chemistry, Kyung Hee University, a team led by professor Janghyuk Moon of School of Energy Systems Engineering, Chung-Ang University, and a team led by professor Seung-kKiSeoung-Ki Lee of School of Materials Science and Engineering, ...
Singapore, 30 July 2024 — Amid the rise of chronic diseases, such as heart disease and diabetes, a novel study by Duke-NUS Medical School offers a fresh perspective on encouraging healthier grocery shopping. Despite the widespread use of colour-coded front-of-pack nutrition labels aimed to help consumers make healthier choices, these measures have not been sufficient to stem the rising tide of chronic diseases.
To determine if adding behavioural nudges and financial incentives could improve diet quality, researchers from Duke-NUS’ Health Services and Systems Research Programme conducted a randomised trial using an experimental online grocery store called NUSMart.
During ...
The results, utilizing National Center for Health Statistics for Asian Americans or Pacific Islander youth ages 10-19 years who died by suicide, were published in the July 25 issue of JAMA Network Open.
The study authors — Brian TaeHyuk, the Buehler Family Sesquicentennial Endowed Assistant Professor at BC’s Lynch School of Education and Human Development; Seungbin Oh, an assistant professor in the Mental Health Counseling and Behavioral Medicine Program at Boston University; and Arielle ...
Published Research from the Parkinson’s Foundation Shows Genetic Variants Are More Common in People with Parkinson’s Disease Than Originally Thought
The PD GENEration study, which tests for clinically relevant Parkinson’s genetic variants and offers genetic counseling, reached a milestone of 15,000 participants in spring 2024 and highlights the importance of sharing genetic data with participants
NEW YORK & MIAMI (July 30, 2024) – New research has found that genetic variants associated with Parkinson’s disease ...
