CRISPR/Cas9 modifies euglena to create potential biofuel source
Mutant microalgae produce wax esters for biofuel feedstock with improved cold flow
2024-09-13
(Press-News.org)
News about biofuels sometimes mentions used cooking oil as a feedstock, but if these substances contain animal fat, they can solidify in colder temperatures. This happens because, chemically, the fatty acids of these and many other saturated fats have long carbon chains with single bonds. Enter the euglena. An Osaka Metropolitan University team has found a way to have one species of this microalgae produce wax esters with shorter carbon chains than usual.
Using CRISPR/Cas9 to edit the genome of Euglena gracilis, Dr. Masami Nakazawa and her team at the Graduate School of Agriculture’s Department of Applied Biochemistry produced stable mutants that created wax esters two carbons shorter than the wild-type species.
This improvement in the cold flow of the wax esters makes them more applicable as feedstock for biofuels. Among the factors favorable to using Euglena gracilis as a biofuel source are its ability to grow easily through photosynthesis and anaerobic production of wax esters.
“This achievement is expected to serve as a fundamental technology for replacing some petroleum-based production of wax esters with biological sources,” Dr. Nakazawa affirmed.
The findings were published in Bioresource Technology.
###
About OMU
Established in Osaka as one of the largest public universities in Japan, Osaka Metropolitan University is committed to shaping the future of society through “Convergence of Knowledge” and the promotion of world-class research. For more research news, visit https://www.omu.ac.jp/en/ and follow us on social media: X, Facebook, Instagram, LinkedIn.
END
[Attachments] See images for this press release:
ELSE PRESS RELEASES FROM THIS DATE:
2024-09-13
A team led by Dr. Hyeon-Gyun Im and Dr. Dong Jun Kang from the Insulation Materials Research Center of Korea Electrotechnology Research Institute (KERI), in collaboration with Dr. Jung-keun Yoo from KIST and Professor Jong-soon Kim from Sungkyunkwan University, have developed a technology that enhances the performance of binders—often the 'unsung heroes' in the field of secondary batteries—while using environmentally friendly materials. This technology has been published in a prestigious international ...
2024-09-13
CHICAGO (Sept 13, 2024)—Menopause is a natural life transition occurring when many women are at the “top of their game.” Unsupported menopause symptoms drive up employer healthcare costs and cause roughly $1.8 billion in missed workdays. To help employers retain these valued workers and build cultures of well-being, The Menopause Society launched Making Menopause Work™ based on new science-based Consensus Recommendations. The Recommendations are published online in Menopause, the journal of The Menopause ...
2024-09-13
One of the most promising avenues for actively reducing CO2 levels in the atmosphere is recycling it into valuable chemicals via electrocatalytic CO2 reduction reactions. With a suitable electrocatalyst, this can be achieved under mild conditions and at a low energy cost. Many types of electrocatalysts are being actively investigated, but most suffer from either low electrocatalytic activity, poor selectivity, or low stability.
Metal sulfides might hold the huge potential solution to this puzzle. By combining ionic and covalent characteristics, this unique family of materials offers good catalytic activity and energy efficiency. The ternary metal system is expected to be a better ...
2024-09-13
Kumamoto University’s research team, led by Assistant Professor Kazuto Hatakeyama and Professor Shintaro Ida of Institute of Industrial Nanomaterials, has announced a groundbreaking development in hydrogen ion barrier films using graphene oxide (GO) that lacks internal pores. This innovative approach promises significant advancements in protective coatings for various applications.
In their study, the research team successfully synthesized and developed a thin film from a new form of graphene oxide that does not contain pores. Traditionally, ...
2024-09-13
Since many kinds of wildlife have started living in urban environments, urban environments have been recognized as places of biodiversity conservation. What kind of factors facilitate or prohibit wildlife from living in urban environments? Understanding the population genetic structure of urban wildlife living would suggest the hint. In this study, we investigated the population genetic structure of Eurasian red squirrels living in urban to rural areas in Obihiro City, Hokkaido, Japan. As a result, we found that ...
2024-09-13
Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid cancers.
The investigational mRNA cancer immunotherapy is targeted for patients with lung cancer, melanoma and other solid tumours. Nineteen patients with advanced stage cancers received between one and nine doses of the immunotherapy treatment. Scientists have found the immunotherapy created an immune response against cancer and was well tolerated, with adverse events ...
2024-09-13
(Jackson, Wyoming – Embargoed until Thursday 12 September 2024 8:00 PM EDT)
A highly accurate diagnostic blood test has been developed for amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease that effects neurons in the brain and spinal cord.
ALS leads to gradual paralysis, ultimately resulting in the inability to walk, speak, or, in later stages, move. Currently, diagnosis is based on a thorough clinical examination, but it can take up to 12 months to provide a definitive diagnosis, by which time many patients have significantly ...
2024-09-12
Without immediate action, humanity will potentially face further escalation in resistance in fungal disease, a renowned group of scientists from the across the world has warned. The commentary - published in The Lancet this week - was coordinated by scientists at The University of Manchester, the Westerdijk Institute and the University of Amsterdam. According to the scientists most fungal pathogens identified by the World Health Organisation - accounting for around 3.8 million deaths a year - are either already resistant or rapidly acquiring resistance to antifungal drugs.
The authors argue that the currently narrow focus on bacteria will not fully combat antimicrobial resistance ...
2024-09-12
Review in The Lancet finds that one in five globally are at risk of contracting cardiovascular diseases, because they carry a genetic risk of high levels of a specific lipoprotein, which can be tested for and possibly treated.
20 % of the world population carries a genetic risk factor for cardiovascular diseases such as heart attacks, strokes, and aortic valve stenosis: Increased levels of a lipid particle called lipoprotein(a). It is the most common genetic cause of cardiovascular diseases.
“Lipoprotein(a) is the direct cause of cardiovascular diseases much like cigarettes cause ...
2024-09-12
Huge gamma-ray burst collection 'rivals 250-year-old Messier catalogue'
Royal Astronomical Society press release
RAS PR 24/24
Embargoed until 00:01 BST on Friday 13 September 2024
Hundreds of gamma-ray bursts (GRBs) have been recorded as part of an enormous global effort so extensive it "rivals the catalogue of deep-sky objects created by Messier 250 years ago", astronomers say.
GRBs are the most violent explosions in the Universe, releasing more energy than the Sun would in 10 billion years. They occur when either a massive star dies or two neutron stars merge.
The explosions are so ...
LAST 30 PRESS RELEASES:
[Press-News.org] CRISPR/Cas9 modifies euglena to create potential biofuel source
Mutant microalgae produce wax esters for biofuel feedstock with improved cold flow