PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Critique 029: What should we advise about alcohol consumption? A debate amongst scientists

2011-01-19
(Press-News.org) A Letter to the Editor entitled "What should we advise about alcohol consumption?" was recently published by Maurizio Ponz de Leon in Intern Emerg Med.1 Dr. de Leon argues that the message of health benefits of moderate drinking "seems to me hazardous and extremely dangerous to diffuse in the general population." His reasons included (1) many people may be unable to distinguish between low–moderate and high consumption of wine, beer or spirits, and alcohol metabolism may differ remarkably from one subject to another; (2) alcohol remains a frequent cause of car crash, and governments (in almost all western countries) try to convince or force people to abstain from drinking before driving; and (3) to consider alcohol as a medication whose consumption may contribute to improved health is another source of concern. Dr. de Leon asks: "Are we truly at the point of prescribing alcohol consumption in order to reduce the risk of stroke and coronary damage?" He concluded "more studies are needed before we can give sensible recommendations on alcohol consumption to the general population."

The de Leon editorial has prompted considerable response from other scientists, including further Letters to the Editor of the journal by Di Castelnuovo, Costanzo, Donati, Iacoviello, and de Gaetano,2 and by Estruch and Lamuela-Raventos.3 In addition, the original editorial has stimulated considerable debate among members of the International Scientific Forum on Alcohol Research. Among key arguments presented by the Forum members, all experts in scientific research on alcohol, are that messages to the public should not be "paternalistic" (we will tell you what is best for you since you are not smart enough to understand the facts), and that guidelines must always be based on sound, balanced scientific data rather than on uninformed opinion. Forum members emphasized that there are certain people who should not drink at all (including former abusers of drugs or alcohol, people with certain medical conditions, children and adolescents, and people with religious or moral proscriptions against alcohol), and there can never be a general recommendation for everybody to consume alcohol. On the other hand, physicians should not withhold from their patients and the public scientifically sound and balanced data on alcohol and health. And the data are extremely strong supporting a role for moderate alcohol intake, for appropriate adults, for the reduction in risk of coronary artery disease and other diseases of ageing.

Several Forum members pointed out that it was unfortunate that the journal had chosen to publish the original letter that castigates alcohol from an author with good scientific credentials, but little to no apparent research expertise in the subject of alcohol and health. Many Forum members disagreed with the statement of de Leon that "Many people may be unable to distinguish between low–moderate and high consumption of wine, beer or spirits." A leading scientist dealing with this subject for decades, Dr. Arthur Klatsky, has written: "Most people know very well what the difference is between light to moderate drinking and binge or excessive drinking. While some patients may rationalize their heavy drinking because of its purported health effects, I have yet to find someone who had developed alcohol abuse because of messages about the health effects of moderate drinking." Medical practitioners, in his view, "have a 'solemn duty' to tell the truth about alcohol consumption, as they understand it, to all of their patients." While pointing out that certain individuals will not benefit from the consumption of alcohol, several Forum members believed that it would be unethical for physicians to withhold from middle-aged or elderly subjects at risk of cardiovascular disease information on the potential benefits of light-to-moderate drinking

INFORMATION:

References:

1. Maurizio Ponz de Leon. What should we advise about alcohol consumption? Intern Emerg Med, DOI 10.1007/s11739-010-0487-1.

2. Augusto Di Castelnuovo, Simona Costanzo, Maria Benedetta Donati, Licia Iacoviello, Giovanni de Gaetano. What should we advise about alcohol consumption? Reply letter by A. Di Castelnuovo. Intern Emerg Med, DOI 10.1007/s11739-010-0502-6.

3. Ramon Estruch, Rosa Ma Lamuela-Raventos. What should we advise about alcohol consumption: reply letter by R. Estruch. Intern Emerg Med; DOI 10.1007/s11739-010-0503-5.

Contributions to this critique by the International Scientific Forum on Alcohol Research were provided by the following members:

Francesco Orlandi, MD, Dept. of Gastroenterology, Università degli Studi di Ancona. Italy

Fulvio Ursini, MD, Dept. of Biological Chemistry, University of Padova, Padova, Italy

R. Curtis Ellison, MD, Section of Preventive Medicine & Epidemiology, Boston University School of Medicine, Boston, MA, USA

Arne Svilaas, MD, PhD, general practice and lipidology, Oslo University Hospital, Oslo, Norway

Harvey Finkel, MD, Hematology/Oncology, Boston University Medical Center, Boston, MA, USA

Andrew L. Waterhouse, PhD, Marvin Sands Professor, Department of Viticulture and Enology, University of California, Davis

Erik Skovenborg, MD, Scandinavian Medical Alcohol Board, Practitioner, Aarhus, Denmark

Maritha J. Kotze, PhD, Human Genetics, Dept of Pathology, and David Van Velden, MD, Dept. of Pathology, University of Stellenbosch, South Africa

Ulrich Keil, MD, PhD, Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany

Tedd Goldfinger, DO, FACC, Desert Cardiology of Tucson Heart Center, Dept. of Cardiology, University of Arizona School of Medicine, Tucson, Arizona, USA

For the detailed critique of this paper by the International Scientific Forum on Alcohol Research: http://www.bu.edu/alcohol-forum/critique-029-differing-opinions-on-the-message-to-the-public-regarding-alcohol-consumption16-january-2011/

The 40 alcohol and health specialists who are members of the Forum are happy to respond to questions from Health Editors regarding emerging research on alcohol and health and will offer an independent opinion in context with other research on the subject.

END



ELSE PRESS RELEASES FROM THIS DATE:

Self-control and choices: Why we take the easy path after exerting ourselves

2011-01-19
After a rough day at the office, you might opt for a convenient, pretty restaurant over one with a top-notch menu, according to a new study in the Journal of Consumer Research. "If you've had a tough day at work, how will that affect the decisions you make, like where to eat, what to do, and what to buy?" ask authors Echo Wen Wan (University of Hong Kong) and Nidhi Agrawal (Northwestern University). Their research revealed that people who are tired from a demanding task will tend to pass up the most desirable choices and go for options that seem to have attractive low-level ...

Young couples can't agree on whether they have agreed to be monogamous

2011-01-19
CORVALLIS, Ore. – While monogamy is often touted as a way to protect against disease, young couples who say they have discussed monogamy can't seem to agree on what they decided. And a significant percentage of those couples who at least agreed that they would be monogamous weren't. A new study of 434 young heterosexual couples ages 18-25 found that, in 40 percent of couples, only one partner says the couple agreed to be sexually exclusive. The other partner said there was no agreement. Public health researchers Jocelyn Warren and Marie Harvey of Oregon State University ...

Loss of reflectivity in the Arctic doubles estimate of climate models

2011-01-19
CORVALLIS, Ore. – A new analysis of the Northern Hemisphere's "albedo feedback" over a 30-year period concludes that the region's loss of reflectivity due to snow and sea ice decline is more than double what state-of-the-art climate models estimate. The findings are important, researchers say, because they suggest that Arctic warming amplified by the loss of reflectivity could be even more significant than previously thought. The study was published online this week in Nature Geoscience. It was funded primarily by the National Science Foundation, with data also culled ...

New technology provides first view of DNA damage within entire human genome

2011-01-19
New technology providing the first view of DNA damage throughout the entire human genome developed by Cardiff University scientists could offer a valuable new insight into the development and treatment of conditions like cancer. Professor Ray Waters, Dr Simon Reed and Dr Yumin Teng from Cardiff University's Department of Genetics, Haematology and Pathology have developed a unique way of measuring DNA damage frequency using tiny microarrays. Using the new method Cardiff scientists can, for the first time, examine all 28,000 human genes where previous techniques have ...

New study shows soy protein lowers non-HDL cholesterol significantly more than milk protein

2011-01-19
Soy protein's ability to lower total and LDL (low-density lipoprotein or "the bad") cholesterol has been extensively studied, but the mechanism whereby soy protein lowers cholesterol remains unresolved. A new study published in the Journal of Clinical Lipidology last month shows that soy protein lowers total cholesterol and non-HDL (non-high-density lipoprotein) cholesterol significantly more than milk protein in patients with moderately high cholesterol levels. "Non-HDL cholesterol has been shown to be a somewhat stronger predictor of cardiovascular disease and mortality ...

Researchers unlock how progesterone increases breast cancer risk

Researchers unlock how progesterone increases breast cancer risk
2011-01-19
EAST LANSING, Mich. — Researchers have identified how the hormones progesterone and estrogen interact to increase cell growth in normal mammary cells and mammary cancers, a novel finding that may explain why postmenopausal women receiving hormone replacement therapy with estrogen plus progestin are at increased risk of breast cancer. The discovery that both estrogen and progesterone must be present for the increased production of the protein amphiregulin, which binds to mammary cells and promotes cell growth, could lead to new treatment methods for the disease, said Sandra ...

'Selective strategy' recommended for CT scans in emergency departments

2011-01-19
CINCINNATI--Emergency medicine researchers with the University of Cincinnati (UC) are advocating a new strategy for diagnosing a common but dangerous condition in the emergency room. Pulmonary embolism, or PE, is a potentially lethal disease in which a blood clot, usually from the legs, travels to the lungs and becomes lodged in a pulmonary artery. But the most common way of testing for PEs, a computed tomography angiography (CTA), comes with so many side effects that researchers in emergency medicine are now looking for ways to reduce use of the test. In a CTA, a contrast ...

EARTH: How dinosaurs arose

2011-01-19
Ask your kid what happened to the dinosaurs, and he or she will likely tell you that an asteroid killed them all. But ask how dinosaurs rose to prominence and you'll likely get a blank stare. Even many paleontologists may have little to say about the subject. But now, as EARTH explores in a feature in the February issue, new fossil discoveries are revealing the backstory of the rise of dinosaurs. Learn more about this eye-opening subject in February's article "Triassic Park: On the Origin of Dinosaur Species," and read other analytical stories on topics such as what OPEC's ...

When you can't walk fast enough to cross busy streets

2011-01-19
CHICAGO --- When a traffic light at a busy intersection flashes the WALK sign, people with knee osteoarthritis worry they can't walk fast enough to make it across the street in time. New Northwestern Medicine research shows people with this common arthritis are more likely to walk fast enough if they lead physically active lives. "The more active people are, the faster they can walk," said Dorothy Dunlop, associate professor of medicine at Northwestern University Feinberg School of Medicine and lead author of the study. "This is strong evidence that even a small increase ...

Chaperone enzyme provides new target for cancer treatments

2011-01-19
UNC scientists who study how cells repair damage from environmental factors like sunlight and cigarette smoke have discovered how a "chaperone" enzyme plays a key role in cells' ability to tolerate the DNA damage that leads to cancer and other diseases. The enzyme, known as Rad18, detects a protein called DNA polymerase eta (Pol eta) and accompanies it to the sites of sunlight-induced DNA damage, enabling accurate repair. When Pol eta is not present, alternative error-prone polymerases take its place – a process that leads to DNA mutations often found in cancer cells. ...

LAST 30 PRESS RELEASES:

Scientists unlock secrets behind flowering of the king of fruits

Texas A&M researchers illuminate the mysteries of icy ocean worlds

Prosthetic material could help reduce infections from intravenous catheters

Can the heart heal itself? New study says it can

Microscopic discovery in cancer cells could have a big impact

Rice researchers take ‘significant leap forward’ with quantum simulation of molecular electron transfer

Breakthrough new material brings affordable, sustainable future within grasp

How everyday activities inside your home can generate energy

Inequality weakens local governance and public satisfaction, study finds

Uncovering key molecular factors behind malaria’s deadliest strain

UC Davis researchers help decode the cause of aggressive breast cancer in women of color

Researchers discovered replication hubs for human norovirus

SNU researchers develop the world’s most sensitive flexible strain sensor

Tiny, wireless antennas use light to monitor cellular communication

Neutrality has played a pivotal, but under-examined, role in international relations, new research shows

Study reveals right whales live 130 years — or more

Researchers reveal how human eyelashes promote water drainage

Pollinators most vulnerable to rising global temperatures are flies, study shows

DFG to fund eight new research units

Modern AI systems have achieved Turing's vision, but not exactly how he hoped

Quantum walk computing unlocks new potential in quantum science and technology

Construction materials and household items are a part of a long-term carbon sink called the “technosphere”

First demonstration of quantum teleportation over busy Internet cables

Disparities and gaps in breast cancer screening for women ages 40 to 49

US tobacco 21 policies and potential mortality reductions by state

AI-driven approach reveals hidden hazards of chemical mixtures in rivers

Older age linked to increased complications after breast reconstruction

ESA and NASA satellites deliver first joint picture of Greenland Ice Sheet melting

Early detection model for pancreatic necrosis improves patient outcomes

Poor vascular health accelerates brain ageing

[Press-News.org] Critique 029: What should we advise about alcohol consumption? A debate amongst scientists