(Press-News.org) PHILADELPHIA — While recovering from major surgery, Black patients may be less likely to receive certain multimodal analgesia options and more likely to receive oral opioids than white patients, according to research being presented at the ANESTHESIOLOGY® 2024 annual meeting.
Multimodal analgesia, which uses multiple types of pain medication to reduce pain, has been shown to be more effective at treating postsurgical pain than a single medication alone, particularly after complex surgeries such as lung or abdominal cancer surgery and hernia repair. Multimodal analgesia is used to improve pain control while reducing the side effects that may come with opioids.
In the retrospective study, Black patients were 29% less likely than white patients to receive multimodal anesthesia using a combination of four drugs. Additionally, while almost all patients received at least one dose of an opioid intravenously (IV), Black patients were 74% more likely than white patients to receive oral opioids in addition to IV opioids.
“We know that multimodal analgesia provides more effective pain management with less need for opioids, which are highly addictive. It should be standard practice, especially in high-risk surgical patients,” said Niloufar Masoudi, M.D., MPH, lead author of the study, anesthesiologist and research assistant at Johns Hopkins University, Baltimore. “We strive to provide patients the most effective pain control while using fewer opioids. Although the optimal number of drug combinations for multimodal analgesia is unknown, using four different types of pain medication vs. two or three may better help to achieve this goal. However, more research is needed.”
The authors compared the postsurgical pain management received by 2,460 white patients and 482 Black patients in the intensive care unit for the first 24 hours after complex, high-risk surgeries that occurred between 2016 and 2021 at one institution. They defined multimodal analgesia as the receipt of an opioid plus at least one other form of pain medication, such as a local anesthetic (epidural or pain patch placed on the skin), nonsteroidal anti-inflammatory drug (NSAID), IV ketamine or oral gabapentin. The researchers ruled out other reasons for the difference they observed with reasonable confidence (e.g., insurance, health conditions, age, etc.).
Several factors may have contributed to the disparity, including differences in pain reported by the patient, patient preferences for or against a form of pain management and practitioner bias for or against forms of pain management by race, Dr. Masoudi said.
“Further research needs to be done to understand the specific cause for the differences in multimodal analgesia between Black and white patients so recommendations can be developed. Additionally, research should be conducted in other ethnic groups to assess whether they are impacted by similar disparities,” said Dr. Masoudi. “In the meantime, pain specialists need to understand the benefits of multimodal analgesia, recognize the existence of disparities in its use and develop standardized protocols to ensure all patients receive this preferred form of pain management when medically appropriate.”
*** ANESTHESIOLOGY 2024 news releases may contain updated data that was not originally available at the time abstracts were submitted.
THE AMERICAN SOCIETY OF ANESTHESIOLOGISTS
Founded in 1905, the American Society of Anesthesiologists (ASA) is an educational, research and scientific society with more than 58,000 members organized to advance the medical practice of anesthesiology and secure its future. ASA is committed to ensuring anesthesiologists evaluate and supervise the medical care of all patients before, during, and after surgery. ASA members also lead the care of critically ill patients in intensive care units, as well as treat pain in both acute and chronic settings.
For more information on the field of anesthesiology, visit the American Society of Anesthesiologists online at asahq.org. To learn more about how anesthesiologists help ensure patient safety, visit asahq.org/madeforthismoment. Join the ANESTHESIOLOGY® 2024 social conversation today. Like ASA on Facebook, follow ASALifeline on X and use the hashtag #ANES24.
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About The Article: This article presents the 2024 revision of the World Medical Association’s Declaration of Helsinki, a set of principles to guide the ethical treatment of participants in medical research.
Corresponding Author: World Medical Association (wma@wma.net).
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2024.21972)
Editor’s Note: Please see the article for additional information, including other authors, author contributions ...
About The Study: This article examines ethical oversight of clinical research in the U.S. and offers practical recommendations that are consistent with current regulations and that could help to make research oversight better fit for purpose for different types of studies.
Corresponding Author: To contact the corresponding author, Nancy E. Kass, ScD, email nkass@jhu.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2024.0269)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, ...
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