PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Cerebral embolic protection by geographic region

JAMA Cardiology

2024-10-29
(Press-News.org)

About The Study: The PROTECTED transcatheter aortic valve replacement (TAVR) trial could not show that the use of cerebral embolic protection (CEP) had a significant effect on the incidence of periprocedural stroke during TAVR. Although there was no significant interaction by geographic region, this exploratory post hoc analysis suggests a trend toward greater stroke reduction in the U.S. cohort but not in the outside the U.S. cohort. These findings are hypothesis generating, and further research is needed to determine if regional differences in patient characteristics or procedural practices affect CEP efficacy. 

Corresponding Author: To contact the corresponding author, Raj R. Makkar, MD, email raj.makkar@cshs.org.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamacardio.2024.4278)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamacardiology/fullarticle/10.1001/jamacardio.2024.4278?guestAccessKey=323860f8-c29c-4d58-ad6f-728382ca987a&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=102924

END



ELSE PRESS RELEASES FROM THIS DATE:

12 new Oriental weevil species discovered using advanced imaging tools

12 new Oriental weevil species discovered using advanced imaging tools
2024-10-29
Jake Lewis, an entomologist in the Environmental Science and Informatics Section at the Okinawa Institute of Science and Technology (OIST), is fascinated by weevils, a diverse group of beetles that includes many species with elephant trunk-like mouthparts (called a rostrum). Weevils provide various ecosystem services such as pollination and decomposition, but some species are serious pests known to decimate crop fields and timber forests. Using x-ray microtomography, a 3D imaging technique ...

Ultrasound can be used as search and rescue tool for the brain

Ultrasound can be used as search and rescue tool for the brain
2024-10-29
Ultrasound, once used almost exclusively to take images of the body, is quickly developing into a targeted therapy that can have a potentially life-changing impact on our brains, according to the authors of a new article. For decades, health professionals across the world have used ultrasound as a means of monitoring the development of unborn babies and assessing the health of patients’ internal organs. But writing in the journal PLOS Biology, researchers from Stanford University, the University of Plymouth, and Attune Neurosciences say it has now been demonstrated to offer a non-invasive and precise way of targeting ...

Department of Defense funds study of gene therapy for muscular degeneration

Department of Defense funds study of gene therapy for muscular degeneration
2024-10-29
The U.S. Department of Defense awarded just under $514,000 to an interdisciplinary team of researchers at the U of A to study the efficacy of “self-delivering” gene editors in the treatment of Duchenne Muscular Dystrophy, or DMD.  DMD results from a mutation in the dystrophin gene and is one of the most severe inherited muscular dystrophies, leading to deterioration of the muscle fibers. Presently, there is no cure, but advances in treatment have helped patients live longer, better lives. Gene therapy designed to ...

People’s exposure to toxic chemicals declined in the U.S. following listing under California law

2024-10-29
With growing concern about the ubiquity of toxic chemicals in consumer products, many states have passed laws aimed at protecting people from harmful substances in everyday items like cosmetics, cleaning supplies, plastics, and food packaging. California’s Proposition 65, for instance, is considered one of the most extensive toxics laws in the country. But does the law work? According to a new study published in the journal Environmental Health Perspectives, it does. “Not only have people’s exposures to specific toxic chemicals gone down in California, ...

Trauma, homelessness afflict gender affirming care patients at higher rates

2024-10-29
A survey of patients receiving gender affirming care shows that commercial insurance pays for most of their treatments, they receive less care in the South than other parts of the U.S. and they deal with disproportionate levels of housing insecurity and trauma compared to others, according to a new study by researchers at the Colorado School of Public Health and the University of Colorado Anschutz Medical Campus. The study, using data provided by Kythera Labs, a healthcare clearinghouse, examined millions of insurance claims by patients undergoing gender affirming care (GA) and those not. It also looked at social determinants of healthcare (SDOH), non-medical factors ...

New $5 million DoE award supports KU startup’s green hydrogen energy research

New $5 million DoE award supports KU startup’s green hydrogen energy research
2024-10-29
LAWRENCE — With $5 million in support from the U.S. Department of Energy, the University of Kansas and Avium — a startup firm founded by researchers from KU’s School of Engineering — aim to make clean hydrogen more affordable. According to the DoE, the work at KU is part of $750 million in funding for 52 projects across 24 states “to dramatically reduce the cost of clean hydrogen and reinforce American leadership in the growing hydrogen industry.” Green hydrogen is a key tool in the worldwide ...

A navigation system for microswimmers

A navigation system for microswimmers
2024-10-29
Microswimmers often need to independently navigate narrow environments like microchannels through porous media or blood vessels. The swimmers can be of biological origin, like algae or bacteria, but also constitute custom designed structures used for the transport of chemicals and drugs. In these cases, it is important to control how they swim in relation to walls and boundaries - as one might want them to exchange fuel or information, but also avoid them to stick where they are not supposed to. Many swimmers are electrically ...

Study finds early TAVR can be beneficial for patients with asymptomatic severe aortic stenosis

2024-10-29
WASHINGTON, DC – OCTOBER 28, 2024 – The first powered randomized trial examining early intervention with transcatheter aortic valve replacement (TAVR) in patients with asymptomatic, severe aortic stenosis (AS) found this strategy to be both a safe and effective alternative to clinical surveillance (CS). Findings were reported today at TCT 2024, the annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT is the world’s premier educational meeting specializing in interventional ...

Implantable microparticles can deliver two cancer therapies at once

Implantable microparticles can deliver two cancer therapies at once
2024-10-29
Patients with late-stage cancer often have to endure multiple rounds of different types of treatment, which can cause unwanted side effects and may not always help. In hopes of expanding the treatment options for those patients, MIT researchers have designed tiny particles that can be implanted at a tumor site, where they deliver two types of therapy: heat and chemotherapy. This approach could avoid the side effects that often occur when chemotherapy is given intravenously, and the synergistic effect of the two therapies ...

Early intervention in patients with asymptomatic severe aortic stenosis and myocardial fibrosis falls short of expected benefits

2024-10-29
WASHINGTON, DC – OCTOBER 28, 2024 – The EVOLVED trial found that early aortic valve intervention in patients with asymptomatic severe aortic stenosis (AS) and mid-wall myocardial fibrosis on magnetic resonance imaging did not reduce the incidence of the composite primary endpoint of all-cause death or unplanned aortic stenosis hospitalization compared with guideline-directed conservative management.   Findings were reported today at TCT 2024, the annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT is the world’s premier educational meeting specializing in interventional cardiovascular ...

LAST 30 PRESS RELEASES:

Fig trees convert atmospheric CO2 to stone

Intra-arterial tenecteplase for acute stroke after successful endovascular therapy

Study reveals beneficial microbes that can sustain yields in unfertilized fields

Robotic probe quickly measures key properties of new materials

Climate change cuts milk production, even when farmers cool their cows

Frozen, but not sealed: Arctic Ocean remained open to life during ice ages

Some like it cold: Cryorhodopsins

Demystifying gut bacteria with AI

Human wellbeing on a finite planet towards 2100: new study shows humanity at a crossroads

Unlocking the hidden biodiversity of Europe’s villages

Planned hydrogen refuelling stations may lead to millions of euros in yearly losses

Planned C-sections increase the risk of certain childhood cancers

Adults who have survived childhood cancer are at increased risk of severe COVID-19

Drones reveal extreme coral mortality after bleaching

New genetic finding uncovers hidden cause of arsenic resistance in acute promyelocytic leukemia

Native habitats hold the key to the much-loved smashed avocado’s future

Using lightning to make ammonia out of thin air

Machine learning potential-driven insights into pH-dependent CO₂ reduction

Physician associates provide safe care for diagnosed patients when directly supervised by a doctor

How game-play with robots can bring out their human side

Asthma: patient expectations influence the course of the disease

UNM physician tests drug that causes nerve tissue to emit light, enabling faster, safer surgery

New study identifies EMP1 as a key driver of pancreatic cancer progression and poor prognosis

XPR1 identified as a key regulator of ovarian cancer growth through autophagy and immune evasion

Flexible, eco-friendly electronic plastic for wearable tech, sensors

Can the Large Hadron Collider snap string theory?

Stuckeman professor’s new book explores ‘socially sustainable’ architecture

Synthetic DNA nanoparticles for gene therapy

New model to find treatments for an aggressive blood cancer

Special issue of Journal of Intensive Medicine analyzes non-invasive respiratory support

[Press-News.org] Cerebral embolic protection by geographic region
JAMA Cardiology