(Press-News.org) About The Study: In patients with acute large vessel occlusion presenting between 4.5 and 24 hours of symptom onset, intra-arterial tenecteplase after successful thrombectomy had a greater likelihood of excellent neurological outcome at 90 days without increasing the risk of symptomatic intracranial hemorrhage or mortality. However, because none of the secondary efficacy analyses supported the primary finding, further trials are needed to confirm the results.
Corresponding Authors: To contact the corresponding authors, email Xiaochuan Huo, PhD, (huoxiaochuan@126.com) and Bernard Yan, MD, (bernard.yan@mh.org.au).
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2025.10800)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
Media advisory: This study is being presented at the 11th Annual Conference of the Chinese Stroke Association & Tiantan International Stroke Conference 2025.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.10800?guestAccessKey=b2e85b97-db58-4e31-af3c-483b2252fee7&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=070525
END
Intra-arterial tenecteplase for acute stroke after successful endovascular therapy
JAMA
2025-07-05
ELSE PRESS RELEASES FROM THIS DATE:
Study reveals beneficial microbes that can sustain yields in unfertilized fields
2025-07-04
Despite rice being the staple food for more than half of the world’s population, its cultivation remains highly resource-intensive, requiring large amounts of water and chemical fertilizers. Even as environmental concerns pertaining to global food security and climate change continue to mount, there is a growing interest in finding more sustainable ways to grow this essential crop.
Microbes in plant roots are known to play a vital role in helping plants survive. It’s known that plants can survive in poor soils by recruiting helpful microbes and forming symbiotic relationships, but we still don’t ...
Robotic probe quickly measures key properties of new materials
2025-07-04
Scientists are striving to discover new semiconductor materials that could boost the efficiency of solar cells and other electronics. But the pace of innovation is bottlenecked by the speed at which researchers can manually measure important material properties.
A fully autonomous robotic system developed by MIT researchers could speed things up.
Their system utilizes a robotic probe to measure an important electrical property known as photoconductivity, which is how electrically responsive ...
Climate change cuts milk production, even when farmers cool their cows
2025-07-04
A new study finds extreme heat reduces milk production by up to 10 percent and adding cooling technologies only offsets about half of the loss.
While recent studies have shown climate change will cut crop production, there has been less research into its impacts on livestock. Dairy farmers already know their cows are vulnerable to heat. What will more heat mean? In one of the most comprehensive assessments of heat’s impact on dairy cows, a study in the journal Science Advances finds one day of extreme heat can cut milk production by up to 10 percent. The effects ...
Frozen, but not sealed: Arctic Ocean remained open to life during ice ages
2025-07-04
For years, scientists have debated whether a giant thick ice shelf once covered the entire Arctic Ocean during the coldest ice ages. Now a new study published in Science Advances, challenges this idea as the research team found no evidence for the presence of a massive ~1km ice shelf. Instead, the Arctic Ocean appears to have been covered by seasonal sea ice—leaving open water and life-sustaining conditions even during the harshest periods of cold periods during the last 750,000 years. This discovery gives insights ...
Some like it cold: Cryorhodopsins
2025-07-04
Imagine the magnificent glaciers of Greenland, the eternal snow of the Tibetan high mountains, and the permanently ice-cold groundwater in Finland. As cold and beautiful these are, for the structural biologist Kirill Kovalev, they are more importantly home to unusual molecules that could control brain cells’ activity.
Kovalev, EIPOD Postdoctoral Fellow at EMBL Hamburg’s Schneider Group and EMBL-EBI’s Bateman Group, is a physicist passionate about solving biological problems. He is particularly hooked by rhodopsins, a group of colourful proteins that enable aquatic microorganisms to harness ...
Demystifying gut bacteria with AI
2025-07-04
Gut bacteria are known to be a key factor in many health-related concerns. However, the number and variety of them is vast, as are the ways in which they interact with the body’s chemistry and each other. For the first time, researchers from the University of Tokyo used a special kind of artificial intelligence called a Bayesian neural network to probe a dataset on gut bacteria in order to find relationships that current analytical tools could not reliably identify.
The human body comprises about 30 trillion to 40 trillion cells, but your intestines contain about 100 trillion gut bacteria. Technically, you’re carrying around more cells that aren’t ...
Human wellbeing on a finite planet towards 2100: new study shows humanity at a crossroads
2025-07-04
The peer-reviewed study, The Earth4All Scenarios: Human Wellbeing on a Finite Planet Towards 2100, uses a system dynamics-based modelling approach to explore two future scenarios: Too Little Too Late, and the Giant Leap. The model presented in the paper provides the scientific basis for the analysis and policy recommendations of Earth for All: A Survival Guide for Humanity, published in 2022.
The model’s findings show that under our current ‘business as usual’ conditions – the Too Little Too Late scenario – ...
Unlocking the hidden biodiversity of Europe’s villages
2025-07-04
Villages, often separated from larger towns and cities, consist of clusters of households and a few public buildings. Despite their long history, the biodiversity of European villages has been understudied compared to urban areas, forests, grasslands, or agricultural fields. A new study reveals their biodiversity potential and how nearby landscapes influence biodiversity patterns and human well-being.
This research was led by an international team from the HUN-REN Centre for Ecological Research with 20 other institutes contributing from Hungary, Romania, Germany, and Italy. Published in Nature Sustainability, ...
Planned hydrogen refuelling stations may lead to millions of euros in yearly losses
2025-07-04
As hydrogen infrastructure is rolled out in the EU, refuelling stations must be distributed according to the same principle in all countries. But now a study from Chalmers University of Technology in Sweden points to shortcomings in EU regulations. Using an advanced model, the researchers show that the distribution of refuelling stations may both be incorrectly dimensioned and lead to losses of tens of millions of euros a year in some countries.
By 2030, EU countries must have built hydrogen refuelling stations at least every ...
Planned C-sections increase the risk of certain childhood cancers
2025-07-04
Children born by planned C-section have an increased risk of developing acute lymphoblastic leukaemia (ALL) later in life. This is shown by a study conducted by researchers at Karolinska Institutet. The researchers emphasise that the risk remains low.
The study, published in The International Journal of Cancer, covers nearly 2.5 million children born in Sweden during two periods, 1982 to 1989 and 1999 to 2015. Of these, 15.5 per cent were born by C-section, i.e. nearly 376,000 children. In the entire group, 1,495 children later developed leukaemia.
Using the Medical Birth Register, the ...
LAST 30 PRESS RELEASES:
Intra-arterial tenecteplase for acute stroke after successful endovascular therapy
Study reveals beneficial microbes that can sustain yields in unfertilized fields
Robotic probe quickly measures key properties of new materials
Climate change cuts milk production, even when farmers cool their cows
Frozen, but not sealed: Arctic Ocean remained open to life during ice ages
Some like it cold: Cryorhodopsins
Demystifying gut bacteria with AI
Human wellbeing on a finite planet towards 2100: new study shows humanity at a crossroads
Unlocking the hidden biodiversity of Europe’s villages
Planned hydrogen refuelling stations may lead to millions of euros in yearly losses
Planned C-sections increase the risk of certain childhood cancers
Adults who have survived childhood cancer are at increased risk of severe COVID-19
Drones reveal extreme coral mortality after bleaching
New genetic finding uncovers hidden cause of arsenic resistance in acute promyelocytic leukemia
Native habitats hold the key to the much-loved smashed avocado’s future
Using lightning to make ammonia out of thin air
Machine learning potential-driven insights into pH-dependent CO₂ reduction
Physician associates provide safe care for diagnosed patients when directly supervised by a doctor
How game-play with robots can bring out their human side
Asthma: patient expectations influence the course of the disease
UNM physician tests drug that causes nerve tissue to emit light, enabling faster, safer surgery
New study identifies EMP1 as a key driver of pancreatic cancer progression and poor prognosis
XPR1 identified as a key regulator of ovarian cancer growth through autophagy and immune evasion
Flexible, eco-friendly electronic plastic for wearable tech, sensors
Can the Large Hadron Collider snap string theory?
Stuckeman professor’s new book explores ‘socially sustainable’ architecture
Synthetic DNA nanoparticles for gene therapy
New model to find treatments for an aggressive blood cancer
Special issue of Journal of Intensive Medicine analyzes non-invasive respiratory support
T cells take aim at Chikungunya virus
[Press-News.org] Intra-arterial tenecteplase for acute stroke after successful endovascular therapyJAMA