PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Ochsner Transplant Institute among site collaborators in New England Journal of Medicine HIV-to-HIV kidney transplant study

2024-11-11
(Press-News.org) NEW ORLEANS – The Ochsner Transplant Institute served as one of 26 U.S. transplant centers collaborating in an HIV-to-HIV kidney transplant study published by The New England Journal of Medicine (NEJM). The article, Safety of Kidney Transplantation from Donors with HIV, details findings supporting HIV-to-HIV kidney transplants as safe and just as effective as those using organs from donors without HIV. 

Human immunodeficiency virus, commonly known as HIV, attacks cells in the body that fight infection and there is currently no known cure. In the U.S.,1.2 million people are living with HIV. According to the National Institute of Allergy and Infectious Disease, 20 people die daily while awaiting a transplant, including those with HIV, who may have a higher likelihood than HIV-negative individuals of developing end-stage kidney and liver disease.  

The HIV Organ Policy Equity (HOPE) Act, effective since 2013, legally allows organ transplants from donors with HIV to recipients with HIV within approved clinical research studies. The NEJM article provides further evidence that HIV-to-HIV kidney transplants are safe and effective, paving the way for routine clinical application. Public comments on the proposed rule, Organ Procurement and Transplantation: Implementation of the HOPE Act, are under review by the U.S. Department of Health and Human Services. If enacted, HIV-to-HIV kidney transplants will be authorized as a standard of care clinical procedure, changing status from research use only.  

Jonathan Hand, MD, section head of transplant infectious diseases, served as the site principal investigator at Ochsner, as part of the HOPE in Action multicenter consortium, and co-lead author. In the study, Dr. Hand and fellow researchers assessed 198 kidney transplant recipients with HIV, half who received kidneys from donors living with HIV, while half received kidneys from donors without HIV. The study evaluated primary and secondary outcomes including safety events, patient survival, infection, failure of HIV treatment and organ rejection, finding comparable results between both groups. 

“We are committed to transforming lives through advanced medical research and excellent patient care at Ochsner, and we are excited to offer patients in our region access to these types of research opportunities," said Dr. Hand. "Through the HOPE Act, we know and have seen people with HIV save lives through organ donation. The results of this study again demonstrate patients with HIV have excellent outcomes after kidney transplant if the donor has HIV or is HIV negative. HIV-to-HIV kidney transplant as a standard of care clinical procedure means people with HIV will benefit from a broader range of available organs, improving access and reducing wait times. There are more than 100,000 people on the national transplant waiting list, and any increase in the U.S. donor pool means the waitlist becomes shorter for everyone and more lives are saved, making the study findings even more important."

Under the HOPE Act, Ochsner was able to perform its first HIV-to-HIV kidney and liver transplant in 2019, making the Ochsner Transplant Institute the first transplant center in Louisiana and the region to offer an HIV-to-HIV liver and/or kidney transplant procedure. This pioneering science and patient care aligns with Ochsner's mission of healthcare accessibility for all people. The Ochsner Transplant Institute is the premier transplant center in the Gulf South region, renowned for its comprehensive range of transplant programs. Offering liver, kidney, pancreas, lung, and heart transplants, Ochsner extends its expertise to pediatric and living donor programs. Since 1984, more than 8,000 life-saving transplants have been performed at the Ochsner Transplant Institute.  

The New England Journal of Medicine is celebrated as the world's premier medical journal, with a distinguished history of over 200 years. It is renowned for delivering high-quality, peer-reviewed research to physicians, educators and medical professionals worldwide. 

For more information about the Ochsner Transplant Institute visit www.ochsner.org/transplant.

###

 

 

About Ochsner Health

Ochsner Health is the leading nonprofit healthcare provider in the Gulf South, delivering expert care at its 46 hospitals and more than 370 health and urgent care centers. For 13 consecutive years, U.S. News & World Report has recognized Ochsner as the No. 1 hospital in Louisiana. Additionally, Ochsner Children’s has been recognized as the No. 1 hospital for kids in Louisiana for four consecutive years. Ochsner inspires healthier lives and stronger communities through a combination of standard-setting expertise, quality and connection not found anywhere else in the region. In 2023, Ochsner Health cared for more than 1.5 million people from every state in the nation and 65 countries. Ochsner’s workforce includes more than 38,000 dedicated team members and over 4,700 employed and affiliated physicians. To learn more about how Ochsner empowers people to get well and stay well, visit https://www.ochsner.org/.  

END



ELSE PRESS RELEASES FROM THIS DATE:

Scientists call for global action on microbial climate solutions

2024-11-11
Washington, D.C. — Nov. 11, 2024 — Today, leaders from scientific societies, institutions and publishing bodies issued an urgent call for the global community and governments to take immediate and decisive emergency climate action. This appeal is made through an editorial published in mSystems, released on the opening day of the 2024 United Nations Climate Change Conference (COP29). Key contributors to this initiative include Virginia Miller, past president of the American Society for Microbiology (ASM); Jack Gilbert, Editor-in-Chief of mSystems; and Jay Lennon, ...

New antibody could be promising cancer treatment

New antibody could be promising cancer treatment
2024-11-11
Researchers at Uppsala University and KTH Royal Institute of Technology have developed a new form of precision medicine, an antibody, with the potential to treat several types of cancer. Researchers have managed to combine three different functions in the antibody, which together strongly amplify the effect of T cells on the cancer tumour. The study has been published in Nature Communications. Researchers have developed a unique type of antibody that both targets and delivers a drug package via the antibody itself, while simultaneously activating the immune system (“3-in-1 design”) for personalised immunotherapy treatments. “We ...

The public implications of private substitutes for electric grid reliability

2024-11-11
Climate change events have, in recent years, placed increasing strain on public electrical grids in the United States. In response to this vulnerability, some consumers are turning to private alternatives to the electric utility, like generators and batteries. A new paper in the Journal of the Association of Environmental and Resource Economists studies who adopts these private alternatives and how adoption responds to grid failures. The paper also studies how public electric grid reliability may change due to this proliferation and how these changes will affect the wellbeing of all households. In ...

Religiosity, spirituality, and meaning-making generally associated with lower suicidality

2024-11-11
November 11, 2024 — All aspects of religiosity, spirituality, and meaning-making (R/S/M) relate to suicidality in people with a psychiatric diagnosis or a recent suicide attempt, according to a systematic review and meta-analysis published in Harvard Review of Psychiatry, part of the Lippincott portfolio from Wolters Kluwer. "Protective dimensions seemed to exert relatively stable effects across different religions and life views," Bart van den Brink, MD, PhD, of the Department of ...

Eife studying legal surveillance as social determinant of health

2024-11-11
Erin Eife, Assistant Professor, Criminology, Law and Society, College of Humanities and Social Sciences (CHSS), received funding for the project: “Surveillance as a Social Determinant of Health: Understanding the Impact of Pending Charges on Health Outcomes.” Eife will conduct this research under the advisement of Evan Lowder, Associate Professor, Criminology, Law and Society, College of Humanities and Social Sciences (CHSS), and Lauren Brinkley-Rubinstein, Associate Professor in the Department of Population Health Sciences at Duke University. Eife aims to produce knowledge about ...

Newly developed 100Gbps data transfer system for accelerating Open Science through industry-university collaboration in Japan

Newly developed 100Gbps data transfer system  for accelerating Open Science through industry-university collaboration in Japan
2024-11-11
Tokyo & Osaka, Japan – Osaka University and NEC Corporation (NEC; TSE: 6701) are moving forward with efforts to realize a data infrastructure supporting Open Science. In 2021, The Joint Research Laboratory for Integrated Infrastructure of High Performance Computing and Data Analysis was established within the D3 Center, Osaka University (Director: Professor Susumu Date*1) by Osaka University and NEC. The result of the Joint Research Laboratory will be showcased at the International Conference for High Performance Computing, Networking, Storage, and Analysis (SC24) scheduled ...

Navigating bias in AI-driven cancer detection

Navigating bias in AI-driven cancer detection
2024-11-11
“As we eagerly adopt Al models, we need to take a moment to think about the potential biases that they may contain.” BUFFALO, NY - November 11, 2024 – A new editorial was published in Oncotarget's Volume 15 on November 7, 2024, titled “ Beyond the hype: Navigating bias in AI-driven cancer detection.” In this editorial, researchers from the Mayo Clinic emphasize the need to address potential biases in Artificial Intelligence (AI) tools used for cancer detection to ensure fair and equitable healthcare. Authors Yashbir Singh, Heenaben Patel, Diana V. Vera-Garcia, Quincy A. Hathaway, ...

Research shows stress about personal finances may make leaders abusive in workplace

Research shows stress about personal finances may make leaders abusive in workplace
2024-11-11
New research from Colorado State University shows that workplace leaders who are financially stressed are more likely to be abusive toward their subordinates – particularly if the leader is a man.  The findings, published in the Journal of Occupational Health Psychology, provide insight into leader behavior due to a common source of stress. The research was led by Assistant Professor Keaton Fletcher in the Department of Psychology in partnership with Associate Professor Trevor Spoelma in the Anderson School of Management at the University ...

Holistic approach of nutrients and traditional natural medicines for human health

2024-11-11
In recent years, there has been a rising interest in combining traditional natural medicines with essential nutrients to foster a holistic approach to human health. The focus on integrating both elements reflects an understanding of health that transcends the simple absence of disease, encompassing physical, mental, and spiritual well-being. This review highlights how traditional medicine systems, such as Ayurveda, Traditional Chinese Medicine (TCM), and other indigenous practices worldwide, can be harmonized with nutritional science to form a comprehensive healthcare approach. Such a combination has the potential to improve disease prevention and enhance overall ...

Study: Online E-cigarette retailers fail to comply with sale regulations

Study: Online E-cigarette retailers fail to comply with sale regulations
2024-11-11
Online e-cigarette retailers are not consistently adhering to laws aimed at preventing the sale of vaping products to minors, including regulations on age verification, shipping methods and flavor restrictions, report researchers at the Herbert Wertheim School of Public Health and Human Longevity Science at University of California San Diego. In a study published online on Nov. 11, 2024 in JAMA, researchers asked 16 people to purchase flavored vape products online and have them delivered to their homes in the County of San Diego, ...

LAST 30 PRESS RELEASES:

How to reduce social media stress by leaning in instead of logging off

Pioneering research shows sea life will struggle to survive future global warming

In 10 seconds, an AI model detects cancerous brain tumor often missed during surgery 

Burden of RSV–associated hospitalizations in US adults, October 2016 to September 2023

Repurposing semaglutide and liraglutide for alcohol use disorder

IPK-led research team provides insights into the pangenome of barley

New route to fluorochemicals: fluorspar activated in water under mild conditions

Microbial load can influence disease associations

Three galactic “red monsters” in the early Universe

First ever study finds sexual and gender minority physicians and residents have higher levels of burnout, lower professional fulfillment

Astronomers discover mysterious ‘Red Monster’ galaxies in the early Universe

The secrets of fossil teeth revealed by the synchrotron: a long childhood is the prelude to the evolution of a large brain

Obesity-fighting drugs may reduce alcohol consumption in individuals with alcohol use disorder

Does AI improve doctors’ diagnoses? Study puts it to the test

Extreme weather accelerates nitrate pollution in groundwater

Burden of liver cancer attributable to hepatitis B and alcohol globally, in China, and for five sociodemographic index regions from 1990 to 2021

Lehigh partners with North Carolina A&T to enhance flood damage mapping with AI and advanced radar

2024 AAAS Kavli Science Journalism Award winners named

Collaborative of prominent academic institutions launches groundbreaking healthcare AI challenge

American Federation for Aging Research announces 2024 AFAR grants for junior faculty

Potential single-dose smallpox and mpox vaccine moves forward

Mass General Brigham Gene and Cell Therapy Institute names Spark Grant recipients

New discovery may lead to more effective treatment for cardiovascular disease

Developing advanced recycling technology to restore spent battery cathode materials

An advance toward inhalable mRNA medications, vaccines

A step toward safer X-rays with new detector technology

On the origin of life: How the first cell membranes came to exist

New evidence-based information from NCCN offers tangible and moral support for people trying to quit smoking

Solving complex problems faster: Innovations in Ising machine technology

Grief-specific cognitive behavioral therapy vs present-centered therapy

[Press-News.org] Ochsner Transplant Institute among site collaborators in New England Journal of Medicine HIV-to-HIV kidney transplant study