PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Oral muvalaplin for lowering of lipoprotein(a)

JAMA

2024-11-18
(Press-News.org) About The Study: Muvalaplin, an oral small molecule lipoprotein(a) inhibitor, reduced lipoprotein(a) measured using intact lipoprotein(a) and apolipoprotein(a)-based assays and was well tolerated. The effect of muvalaplin on cardiovascular events requires further investigation. 

Corresponding Author: To contact the corresponding author, Stephen J. Nicholls, MBBS, PhD, email stephen.nicholls@monash.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2024.24017)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

Media advisory: This study is being presented at the American Heart Association’s Scientific Sessions 2024.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.24017?guestAccessKey=f849b8a2-374c-4de8-87cc-7ee02b84e5f9&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111824

END


ELSE PRESS RELEASES FROM THIS DATE:

Revealing the hidden costs of what we eat

2024-11-18
(Santa Barbara, Calif.) — Shifting our diets to be more sustainable can be a powerful way for each of us to address both climate change and global food insecurity, however making such adjustments at the large scales necessary to make a difference globally can be a delicate matter. “Changes in food demand in one part of the world can have cascading environmental and human welfare implications for people around the world),” said Joe DeCesaro, data analyst at UC Santa Barbara’s National Center for Ecological Analysis & Synthesis (NCEAS). Despite the seemingly daunting complexity of the global food system, to ensure a healthy population ...

New therapies at Kennedy Krieger offer effective treatment for managing Tourette syndrome

2024-11-18
BALTIMORE, November 18, 2024— Researchers at Kennedy Krieger Institute have made significant strides in improving the lives of patients with Tourette syndrome. Their recent publication highlights how behavioral therapies—an approach that teaches patients how to manage certain tics using behavioral strategies—are proving to be the most effective treatment. Tourette syndrome (TS), a neurodevelopmental disorder affecting up to 1% of the population, is characterized by motor and vocal tics, which are sudden, repetitive movements or sounds that can significantly ...

American soil losing more nutrients for crops due to heavier rainstorms, study shows

American soil losing more nutrients for crops due to heavier rainstorms, study shows
2024-11-18
UNIVERSITY PARK, Pa. — Phosphorus, a nutrient in soil essential for sustaining most forms of life, is increasingly disappearing from land as it is washed into waterways throughout the United States, according to a new study led by researchers at Penn State. The study, published today (Nov. 18) in the Proceedings of the National Academy of Sciences, analyzed data from 430 rivers across the U.S. and found that phosphorus loss from agricultural lands has increased over the past four decades, despite efforts to reduce it. This loss of phosphorus ...

With new imaging approach, ADA Forsyth scientists closely analyze microbial adhesive interactions

With new imaging approach, ADA Forsyth scientists closely analyze microbial adhesive interactions
2024-11-18
Cambridge, Mass., 11/18/2024 – Scientists have identified many types of bacteria in the mouth, but many problems remain in understanding how they work with one another. One of the problems is that microbes assemble themselves into densely packed multi-species biofilms. Their density and complexity pose acute difficulties for visualizing individual cells and analyzing their interactions at single-cell level. ADA Forsyth scientists have developed a new imaging approach that makes it possible to analyze the spatial connections between bacteria, including the strength of adhesive forces that hold them together. Adhesion is of fundamental importance in ...

Global antibiotic consumption has increased by more than 21 percent since 2016

2024-11-18
Washington, DC / Bangalore, India — A new study highlights recent, but fluctuating, growth in global human antibiotic consumption, one of the main drivers of growing antimicrobial resistance (AMR). AMR results in infections that no longer respond to antibiotics (and other antimicrobial medicines) and often leads to longer hospital stays, higher treatment costs, and higher mortality rates. AMR is estimated to be associated with nearly five million global deaths annually. Researchers affiliated with the One Health Trust (OHT), the Population Council, GlaxoSmithKline, the University of Zurich, the University of Brussels, ...

New study shows how social bonds help tool-using monkeys learn new skills

New study shows how social bonds help tool-using monkeys learn new skills
2024-11-18
The research team, led by Durham University’s Department of Anthropology, studied two groups of wild bearded capuchin monkeys in Brazil’s Serra da Capivara National Park.  The researchers installed a large box in the park which contained food that the monkeys could access by either lifting a door or pulling a knob.  The team observed which monkeys learned how to access the food, and how that information then spread to the rest of their group.  The researchers specifically focused on the role played by social tolerance in the learning of the problem-solving behaviour.  Social tolerance determines who is allowed ...

Modeling and analysis reveals technological, environmental challenges to increasing water recovery from desalination

2024-11-18
Climate change is making water scarcer. A promising method to combat this problem is desalination technology because it can tap seawater. Though desalination has potential, it also brings risks with environmental impact, cost, and accessibility.  Zero liquid discharge (ZLD) technology aims to increase water recovery from desalination by squeezing more water out of desalination brine. ZLD can help reduce water scarcity and waste from desalination plants, but comes at increased costs and, potentially, increased environmental effects from desalination.  In ...

Navy’s Airborne Scientific Development Squadron welcomes new commander

Navy’s Airborne Scientific Development Squadron welcomes new commander
2024-11-18
WASHINGTON — Cmdr. J. Aaron Roberts relinquished command of the U.S. Naval Research Laboratory’s (NRL) Scientific Development Squadron (VXS) 1, the Warlocks, to Cmdr. Luis A. Levine, the new Commanding Officer (CO), during a change of command and retirement ceremony Nov. 14 at Naval Air Station (NAS) Patuxent River, Maryland. NRL’s CO Capt. Jesse Black presented Roberts with the Meritorious Service Medal. Roberts served as the VXS-1 CO from May 2023 to November 2024 and the U.S. Navy for 21 years. Black said Roberts’ distinguished leadership was instrumental to the squadron’s continued record of exceptional support to NRL’s airborne ...

TāStation®'s analytical power used to resolve a central question about sweet taste perception

TāStation®s analytical power used to resolve a central question about sweet taste perception
2024-11-18
PHILADELPHIA, PA – November 18, 2024 – Opertech Bio, Inc., a leading innovator in taste assessment, today announced the publication of a research article in which the TāStation® rapid throughput taste evaluation system was used to resolve a central question about sweet taste perception. It has been well established that sweeteners impart their taste by activating the TAS1R2/TAS1R3 “sweet taste receptor” in the tongue. A second signaling pathway involving the activity of glucose transporters, operating independently of the receptor, recently has been proposed for metabolizable caloric sweeteners. In a powerful demonstration of the analytical ...

NASA awards SwRI $60 million contract to develop next-generation coronagraphs

NASA awards SwRI $60 million contract to develop next-generation coronagraphs
2024-11-18
Southwest Research Institute has won a $60 million contract to build three coronagraphs for the National Oceanic and Atmospheric Administration (NOAA). SwRI’s novel Space Weather Solar Coronagraph (SwSCOR) is NOAA’s next-generation instrument to provide early detection and characterization of Earth-directed coronal mass ejections (CMEs). CMEs are huge bursts of coronal plasma threaded with intense magnetic fields ejected from the Sun over the course of several hours. CMEs arriving at Earth can generate geomagnetic storms, which can cause anomalies in and disruptions ...

LAST 30 PRESS RELEASES:

Scientists unlock secrets behind flowering of the king of fruits

Texas A&M researchers illuminate the mysteries of icy ocean worlds

Prosthetic material could help reduce infections from intravenous catheters

Can the heart heal itself? New study says it can

Microscopic discovery in cancer cells could have a big impact

Rice researchers take ‘significant leap forward’ with quantum simulation of molecular electron transfer

Breakthrough new material brings affordable, sustainable future within grasp

How everyday activities inside your home can generate energy

Inequality weakens local governance and public satisfaction, study finds

Uncovering key molecular factors behind malaria’s deadliest strain

UC Davis researchers help decode the cause of aggressive breast cancer in women of color

Researchers discovered replication hubs for human norovirus

SNU researchers develop the world’s most sensitive flexible strain sensor

Tiny, wireless antennas use light to monitor cellular communication

Neutrality has played a pivotal, but under-examined, role in international relations, new research shows

Study reveals right whales live 130 years — or more

Researchers reveal how human eyelashes promote water drainage

Pollinators most vulnerable to rising global temperatures are flies, study shows

DFG to fund eight new research units

Modern AI systems have achieved Turing's vision, but not exactly how he hoped

Quantum walk computing unlocks new potential in quantum science and technology

Construction materials and household items are a part of a long-term carbon sink called the “technosphere”

First demonstration of quantum teleportation over busy Internet cables

Disparities and gaps in breast cancer screening for women ages 40 to 49

US tobacco 21 policies and potential mortality reductions by state

AI-driven approach reveals hidden hazards of chemical mixtures in rivers

Older age linked to increased complications after breast reconstruction

ESA and NASA satellites deliver first joint picture of Greenland Ice Sheet melting

Early detection model for pancreatic necrosis improves patient outcomes

Poor vascular health accelerates brain ageing

[Press-News.org] Oral muvalaplin for lowering of lipoprotein(a)
JAMA