Knowledge and worry following review of standard vs patient-centered pathology reports
JAMA
2025-01-02
(Press-News.org)
About The Study: Most study participants could not extract basic information—including whether they have cancer—from standard prostate cancer pathology reports but were able to understand this diagnostic information from the patient-centered pathology reports (PCPRs). Also, they discriminated between risk levels (i.e., lower levels of perceived worry in the low-risk condition) with PCPRs compared with standard reports. Hospital systems should consider including PCPRs with standard pathology reports to improve patient understanding.
Corresponding Author: To contact the corresponding author, Cathryn J. Lapedis, MD, MPH, MS, email cathrynb@med.umich.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2024.25461)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.25461?guestAccessKey=750b4a2a-5207-46ca-b9c1-a6e27b0df59b&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=010225
END
ELSE PRESS RELEASES FROM THIS DATE:
2025-01-02
About The Study: This case-control study found that individuals with more advanced breast cancer at diagnosis were more likely to have prevalent cardiovascular disease. This finding may be specific to hormone receptor–positive and ERBB2-negative (formerly HER2) disease. Future studies are needed to confirm these findings and investigate interventions to improve patient outcomes, including personalized cancer screening.
Corresponding Author: To contact the corresponding author, Kevin T. Nead, MD, MPhil, email ktnead@mdanderson.org.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2024.52890)
Editor’s ...
2025-01-02
PITTSBURGH, Jan. 2, 2025 – University of Pittsburgh researchers uncovered a surprising link between Alzheimer’s disease and herpes simplex virus-1 (HSV-1), suggesting that viral infections may play a role in the disease. The study results are published today in Cell Reports.
The study also revealed how tau protein, often viewed as harmful in Alzheimer’s, might initially protect the brain from the virus but contribute to brain damage later. These findings could lead to new treatments targeting infections and the brain’s immune response.
“Our study challenges ...
2025-01-02
HOUSTON ― Cardiovascular disease (CVD) and cancer are the two leading causes of death in the U.S. According to researchers from The University of Texas MD Anderson Cancer Center, patients diagnosed with late-stage or metastatic breast cancer have a statistically significant increased risk of pre-diagnosis CVD compared to those with early-stage cancer at diagnosis.
The study, published today in JAMA Network Open, found those with advanced breast cancer at diagnosis were 10% more likely to have had pre-existing ...
2025-01-02
Glaucoma is a progressive eye disorder characterized by fluid buildup inside the eye, causing ocular hypertension. By 2040, it is estimated that 111.8 million people worldwide will be affected by glaucoma, potentially leading to blindness if left untreated. Currently, there are treatments available to manage ocular hypertension, but a cure for glaucoma remains elusive.
Retinal ganglion cells (RGCs) are crucial for transmitting visual signals from the eyes to the brain, and their degeneration leads to optic nerve damage, which is a hallmark of glaucoma. In recent years, scientists ...
2025-01-02
Maize is a globally cultivated staple crop and one of the most successful examples of heterosis utilization in food production. The development of elite inbred lines is critical for breeding hybrid varieties and achieving sustained yield improvements. However, efficient breeding of inbred lines faces significant challenges, including the broad origins of germplasm resources, complex and diverse genetic structures, and low accuracy in phenotypic prediction. Advances in modern genomics and artificial intelligence technologies ...
2025-01-02
Pancreatic cancer kills 50,000 people each year, according to the National Cancer Institute, and there are few effective treatment options for the disease. In a new study, researchers at University of California San Diego School of Medicine have discovered that an enzyme called MICAL2 promotes tumor growth and spread in pancreatic ductal adenocarcinomas (PDAC), the most common form of pancreatic cancer. The study will be published on January 2, 2025 in Cancer Research, a journal of the American Association for Cancer Research.
Normally, MICAL2 plays an important role in cell migration and morphology. But when the researchers measured ...
2025-01-02
WHAT:
Highly pathogenic H5N1 avian influenza A virus (HPAI H5N1) remains a low risk to the general public, and public health experts in the United States believe that available treatments and vaccines, as well as those in development, are sufficient to prevent severe disease. However, the National Institutes of Health (NIH) and its federal partners remain focused on monitoring the virus and evaluating changes, according to leading officials at the National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH.
In a commentary published in the New England Journal of Medicine, NIAID Director Jeanne M. Marrazzo, M.D., M.P.H., and Michael G. Ison, M.D., M.S., chief ...
2025-01-02
University of Iowa researchers are recommending all patients be surveyed about their physical activity levels, after a new study underscores the link between physical activity and chronic disease.
The study, led by Lucas Carr, associate professor in the Department of Health and Human Physiology, examined responses from more than 7,000 patients at University of Iowa Health Care Medical Center who noted their level of physical activity in a questionnaire.
From patients’ answers to the questionnaire, the researchers found that those who reported the highest level of physical activity — meaning they exercised moderately ...
2025-01-02
Since 2021, Insilico Medicine has successfully nominated 22 preclinical candidates (PCCs) with the help of its proprietary Pharma.AI platform, among which 5 were nominated just the year of 2024.
The novel scaffold of ISM1745 is based on de novo generation results of Insilico’s Chemistry42, the generative AI platform combining more than 40 generative models.
With in vivo anti-tumor activity validated in multiple cancer models, the candidate compound showed robust in vivo efficacy as monotherapy as well as combination potential with chemotherapies, targeted agents including MAT2A inhibitor, and immunotherapies.
CAMBRIDGE, ...
2025-01-02
Scientists at University of California San Diego School of Medicine have shed new light on the development of liver cancer, the sixth most frequently diagnosed cancer and fourth leading cause of cancer deaths worldwide. The study, published in Nature, reveals a complex interplay between cellular metabolism and DNA damage that drives the progression of fatty liver disease to cancer. The findings suggest new paths forward for preventing and treating liver cancer and have significant implications on our understanding of cancer’s origin and the effects of diet on our DNA.
The incidence of the most common form of liver cancer, hepatocellular carcinoma (HCC), has grown by 25-30% in the past ...
LAST 30 PRESS RELEASES:
[Press-News.org] Knowledge and worry following review of standard vs patient-centered pathology reports
JAMA
