Lifetime health effects and cost-effectiveness of tirzepatide and semaglutide in US adults
JAMA Health Forum
2025-03-14
(Press-News.org)
About The Study: This economic evaluation found that although tirzepatide and semaglutide offered substantial long-term health benefits, they were not cost-effective at current net prices. Efforts to reduce the net prices of new anti-obesity medications are essential to ensure equitable access to highly effective anti-obesity medications.
Corresponding Author: To contact the corresponding author, Jennifer H. Hwang, DO, email jennifer.hwang2@bsd.uchicago.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamahealthforum.2024.5586)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2024.5586?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=031425
END
ELSE PRESS RELEASES FROM THIS DATE:
2025-03-14
CDKL5, one of the five members of the CDKL family of genes, is important for proper neurodevelopment and associated with seizures. However, the role the other four members of this family play in health and disease is unknown.
A team led by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children’s Hospital has deepened our understanding of two other members of the CDKL family, CDKL2 and CDKL1. The labs of Drs. Oguz Kanca and Hugo Bellen show that ...
2025-03-14
A review article published in Engineering delves into the crucial field of organ preservation, exploring its history, current techniques, and future prospects. The shortage of donor organs remains a significant global challenge, with only about 10% of the global demand for organ transplantation being met, as stated by the World Health Organization. This shortage is further exacerbated by the limitations of current organ preservation methods.
Currently, the main clinical methods for organ preservation are static cold storage (SCS) and machine perfusion (MP). SCS, which involves storing organs in a preservation solution at low temperatures (usually 4 °C), is simple and ...
2025-03-14
Researchers at the University of Pittsburgh have identified a novel trigger of a deadly form of ovarian cancer: a subset of progenitor cells that reside in fallopian tube supportive tissue, or stroma.
The discovery of these high-risk cells, described in a new study published today in Cancer Discovery, a journal of the American Association for Cancer Research, could pave the way for better approaches to prevent and detect high-grade serous ovarian cancer (HGSOC), the most common form of ovarian cancer, which kills more than 12,000 women in the U.S. each year.
“Ovarian cancer is the leading cause of death from gynecologic cancer in the Western world, but we currently ...
2025-03-14
WHAT:
Researchers at the National Institutes of Health (NIH) have determined that dermatitis resulting from topical steroid withdrawal (TSW) is distinct from eczema and is caused by an excess of an essential chemical compound in the body. Scientists from NIH’s National Institute of Allergy and Infectious Diseases (NIAID) identified treatments that could be studied in clinical trials for the condition based on their potential to lower levels of the chemical compound—called nicotinamide adenine dinucleotide (NAD+), a form of ...
2025-03-14
SARS-CoV-2, the virus responsible for COVID-19, infects cells by binding its spike protein to angiotensin-converting enzyme 2 (ACE2) receptors. Blocking this interaction with inhibitors could prevent infection. Since these inhibitors act directly on the virus without affecting human cells, they may be safer than some existing treatments. However, mutations in the spike protein can alter its structure, reducing the effectiveness of these inhibitors.
In a significant breakthrough, a research team led by Professor Yoshinori Fujiyoshi ...
2025-03-14
Magnetic materials have become indispensable to various technologies that support our modern society, such as data storage devices, electric motors, and magnetic sensors. High-magnetization ferromagnets are especially important for the development of next-generation spintronics, sensors, and high-density data storage technologies. Among these materials, the iron-cobalt (Fe-Co) alloy is widely used due to its strong magnetic properties. However, there is a limit to how much their performance can be improved, necessitating a new approach.
Some of the earlier studies have shown that epitaxially grown films made up of Fe-Co alloys doped with heavier elements exhibit remarkably high ...
2025-03-14
(Boston)—Digital voice recordings contain valuable information that can indicate an individual’s cognitive health, offering a non-invasive and efficient method for assessment. Research has demonstrated that digital voice measures can detect early signs of cognitive decline by analyzing features such as speech rate, articulation, pitch variation and pauses, which may signal cognitive impairment when deviating from normative patterns.
However, voice data introduces privacy challenges due to the personally identifiable information embedded in recordings, ...
2025-03-14
Researchers at the University of Birmingham have developed a new method for the rapid scalable preparation of uniform nanostructures directly from block polymers.
This novel approach, led by the Dove and O'Reilly groups, significantly reduces processing time from a week to just minutes, enabling high-throughput production of precision polymer nanomaterials.
Publishing their findings today (14 Mar) in Nature Chemistry, the teams outline a rapid seed preparation technique that supersaturates polymer solutions in a flow system.
The process facilitates uniform seed micelle formation and allows ...
2025-03-14
Photosynthesis is a marvellous process: plants use it to produce sugar molecules and oxygen from the simple starting materials carbon dioxide and water. They draw the energy they need for this complex process from sunlight.
If humans could imitate photosynthesis, it would have many advantages. The free energy from the sun could be used to remove carbon dioxide from the atmosphere and use it to build carbohydrates and other useful substances. It would also be possible to produce hydrogen, as photosynthesis splits water into its components oxygen and hydrogen.
Photosynthesis: a Complex Process ...
2025-03-14
People with favourable socioeconomic conditions, such as high incomes or education levels, face a reduced risk of age-related diseases and show fewer signs of biological ageing than peers of the same age, finds a new study led by University College London (UCL) researchers.
Social inequalities appear to have a direct impact on the biological ageing process, according to the authors of the Nature Medicine paper.
The scientists found that people with more social advantages had fewer proteins in their blood that are linked to the ...
LAST 30 PRESS RELEASES:
[Press-News.org] Lifetime health effects and cost-effectiveness of tirzepatide and semaglutide in US adults
JAMA Health Forum