PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Prevalence and severity of astigmatism in children after COVID-19

JAMA Ophthalmology

2025-03-20
(Press-News.org) About The Study: In this study, lifestyle changes after the pandemic were associated with an increase in the prevalence and severity of child astigmatisms, likely associated with changes in the developing cornea. The potential impact of higher degrees of astigmatism may warrant dedicated efforts to elucidate the relationship between environmental and/or lifestyle factors, as well as the pathophysiology of astigmatism.

Corresponding Authors: To contact the corresponding authors, email Jason C. Yam, MD (yamcheuksing@cuhk.edu.hk) and Li Jia Chen, PhD (lijia_chen@cuhk.edu.hk).

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaophthalmol.2025.0205)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaophthalmology/fullarticle/10.1001/jamaophthalmol.2025.0205?guestAccessKey=d70cecc6-f234-4eab-ab32-bd2befbe5763&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=032025

END


ELSE PRESS RELEASES FROM THIS DATE:

Study: new guidelines expanded access to lung cancer screening, but gaps remain in reaching rural and uninsured populations

Study: new guidelines expanded access to lung cancer screening, but gaps remain in reaching rural and uninsured populations
2025-03-20
MIAMI, FLORIDA (STRICTLY EMBARGOED UNTIL MARCH 20, 2025, AT 11 A.M. EDT) – Since 2021, when lung cancer screening guidelines began to include younger people and those with a lower smoking history, the number of screenings climbed, but significant gaps remain, especially among people with limited access to healthcare, according to a new study led by researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine. "The updated guidelines substantially increased lung cancer screenings overall, even as ...

Analysis of new colorectal cancer immunotherapy shows more treatment options

2025-03-20
A team of researchers from Cleveland Clinic Genomic Medicine share insights from an early set of 19,000 patients to receive immune checkpoint inhibitor treatments for colorectal cancer in the U.S.   The report comes from the laboratory of Stephanie Schmit, PhD, MPH, and was published in JAMA Network Open. It serves as an opportunity to better understand how immune checkpoint inhibitor treatments, including PD-1 and PD-L1 inhibitors, work in a larger population that reflects real-world settings. Dr. Schmit collaborated with a team of ...

Scientists use cellular programming to mimic first days of embryonic development

Scientists use cellular programming to mimic first days of embryonic development
2025-03-20
The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery.  The process of how a humble single cell becomes an organism fascinates scientists across disciplines. For some animals, the entire process of cellular multiplication, generation of specialized cells, and their organization into an ordered multicellular embryo takes place in the protective environment of the uterus, making direct observation and studies challenging. This makes it difficult for scientists to understand what can go wrong during that process, and how specific risk factors and the surrounding environment may prevent ...

Potential targeted therapy for pediatric brain cancer identified by Dana-Farber team

2025-03-20
Boston – An international team of clinical collaborators, led by physician scientists from Dana-Farber Cancer Institute, performed a first-ever clinical test of the targeted therapy avapritinib in pediatric and young patients with a form of high-grade glioma. They found that the drug, already FDA-approved for certain adult cancers, was generally safe and resulted in tumor reduction visible on brain scans, as well as clinical improvement, in 3 out of 7 patients. The study was published in Cancer Cell. Pediatric-type high-grade gliomas are currently incurable brain tumors with median survival times less than 18 months after initial diagnosis. Avapritinib ...

Self-assembled vesicles containing podophyllotoxin covalently modified with polyoxometalates for antitumor therapy

Self-assembled vesicles containing podophyllotoxin covalently modified with polyoxometalates for antitumor therapy
2025-03-20
POMs are a class of inorganic metal-oxygen cluster compounds with broad-spectrum antitumor potential. However, their strong hydrophilicity and poor lipophilicity result in insufficient cell membrane permeability, and high doses are required to achieve therapeutic effects, which severely limits their clinical application. To address this challenge, the research team proposes a covalent modification strategy: the construction of an amphipathic drug molecule PPT-POM-PPT by linking the hydrophobic anti-tumor drug Podophyllotoxin (PPT) with hydrophilic POMs. This molecule ...

Circadian rhythms in tumor regulation: Impacts on tumor progression and the immune microenvironment

Circadian rhythms in tumor regulation: Impacts on tumor progression and the immune microenvironment
2025-03-20
Circadian rhythms are endogenous time-keeping mechanisms that regulate physiological processes in response to external light-dark cycles. These rhythms are orchestrated by the suprachiasmatic nucleus (SCN) in the hypothalamus and involve a network of genes, including CLOCK and BMAL1, that influence metabolism, immune responses, and cell proliferation. Recent research has highlighted the crucial role of circadian rhythms in tumor biology, demonstrating that their dysregulation contributes to tumorigenesis, progression, and metastasis. Additionally, circadian rhythms influence the tumor immune microenvironment and the ...

The emerging role of flavonoids in the treatment of type 2 diabetes mellitus: regulating the enteroendocrine system

2025-03-20
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder with a rapidly increasing global prevalence. It is primarily characterized by insulin resistance, β-cell dysfunction, and impaired glucose homeostasis. Emerging research suggests that flavonoids, a diverse group of plant-derived polyphenols, may offer therapeutic potential in managing T2DM. These compounds exert antidiabetic effects through multiple mechanisms, including improving insulin sensitivity, enhancing β-cell function, modulating ...

Improving patient experience for the millions who visit an ED annually

2025-03-20
INDIANAPOLIS -- A large scale study by researchers from the Regenstrief Institute and the Indiana University School of Medicine has found that patient pain upon arrival to the Emergency Department (ED) as well as the use of hallway beds and radiology studies in the ED are associated with patient experience, although not in the same ways. The study’s tens of thousands of observations including clinical and operational data revealed that regardless of how promptly or successfully pain was treated in the ED, the amount of pain the patient was in when they arrived was associated with patient experience ...

Recycled cements drive down emissions without slacking on strength

Recycled cements drive down emissions without slacking on strength
2025-03-20
Giving a second life to construction materials after demolition, engineers at the University of São Paulo and Princeton have developed an approach for recycling cement waste into a sustainable, low-carbon alternative that is comparable in performance to the industry standard. In addition to lowering the carbon intensity of the cement and concrete industry, the process could enable new uses for construction and demolition waste, of which concrete is a significant component. In 2018 in the United States, the total ...

Beyond the cure: Navigating hepatocellular risk and surveillance after hepatitis C eradication in the direct-acting antiviral era

Beyond the cure: Navigating hepatocellular risk and surveillance after hepatitis C eradication in the direct-acting antiviral era
2025-03-20
Hepatitis C virus (HCV) infection remains a major global health burden, affecting millions worldwide and contributing significantly to hepatocellular carcinoma (HCC) development. The introduction of direct-acting antivirals (DAAs) has revolutionized HCV treatment, achieving high rates of sustained virologic response (SVR) and reducing HCV-associated morbidity and mortality. Despite these advancements, the risk of HCC persists in certain populations, particularly those with pre-treatment cirrhosis or advanced fibrosis (F3). This review examines the ...

LAST 30 PRESS RELEASES:

Could electric fields supercharge immune attack on the deadliest form of brain cancer?

Rutgers Health research identifies new trigger accelerating antibiotic resistance

Who gets targeted in online games? Study maps harassment risk by gender, age, and identity

MBARI research and technology play integral role in new Decade of Action for Cryospheric Sciences

Protected Antarctic oceanic life threatened by ships anchoring, first underwater videos show

Pregnant and bearing the burden of measles outbreaks in Canada

Antipsychotic medications reduce vehicle crashes in drivers with schizophrenia

TikTok teen skin-care routines are harmful

Over confidence in finance bosses leads to environmental rule-breaking

From puck drop to brain pop

Urgent policy actions needed to address real AI threats, scientist reveals

FOR IMMEDIATE RELEASE: Mount Sinai experts present research at SLEEP 2025

Medigap protection and plan switching among Medicare advantage enrollees with cancer

Bubbles are key to new surface coating method for lightweight magnesium alloys

Carbon stable isotope values yield different dietary associations with added sugars in children compared to adults

Scientists discover 230 new giant viruses that shape ocean life and health

Hurricanes create powerful changes deep in the ocean, study reveals

Genetic link found between iron deficiency and Crohn’s disease

Biologists target lifecycle of deadly parasite

nTIDE June 2025 Jobs Report: Employment of people with disabilities holds steady in the face of uncertainty

Throughput computing enables astronomers to use AI to decode iconic black holes

Why some kids respond better to myopia lenses? Genes might hold the answer

Kelp forest collapse alters food web and energy dynamics in the Gulf of Maine

Improving T cell responses to vaccines

Nurses speak out: fixing care for disadvantaged patients

Fecal transplants: Promising treatment or potential health risk?

US workers’ self-reported mental health outcomes by industry and occupation

Support for care economy policies by political affiliation and caregiving responsibilities

Mailed self-collection HPV tests boost cervical cancer screening rates

AMS announces 1,000 broadcast meteorologists certified

[Press-News.org] Prevalence and severity of astigmatism in children after COVID-19
JAMA Ophthalmology