PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Prevalence and severity of astigmatism in children after COVID-19

JAMA Ophthalmology

2025-03-20
(Press-News.org) About The Study: In this study, lifestyle changes after the pandemic were associated with an increase in the prevalence and severity of child astigmatisms, likely associated with changes in the developing cornea. The potential impact of higher degrees of astigmatism may warrant dedicated efforts to elucidate the relationship between environmental and/or lifestyle factors, as well as the pathophysiology of astigmatism.

Corresponding Authors: To contact the corresponding authors, email Jason C. Yam, MD (yamcheuksing@cuhk.edu.hk) and Li Jia Chen, PhD (lijia_chen@cuhk.edu.hk).

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaophthalmol.2025.0205)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaophthalmology/fullarticle/10.1001/jamaophthalmol.2025.0205?guestAccessKey=d70cecc6-f234-4eab-ab32-bd2befbe5763&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=032025

END


ELSE PRESS RELEASES FROM THIS DATE:

Study: new guidelines expanded access to lung cancer screening, but gaps remain in reaching rural and uninsured populations

Study: new guidelines expanded access to lung cancer screening, but gaps remain in reaching rural and uninsured populations
2025-03-20
MIAMI, FLORIDA (STRICTLY EMBARGOED UNTIL MARCH 20, 2025, AT 11 A.M. EDT) – Since 2021, when lung cancer screening guidelines began to include younger people and those with a lower smoking history, the number of screenings climbed, but significant gaps remain, especially among people with limited access to healthcare, according to a new study led by researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine. "The updated guidelines substantially increased lung cancer screenings overall, even as ...

Analysis of new colorectal cancer immunotherapy shows more treatment options

2025-03-20
A team of researchers from Cleveland Clinic Genomic Medicine share insights from an early set of 19,000 patients to receive immune checkpoint inhibitor treatments for colorectal cancer in the U.S.   The report comes from the laboratory of Stephanie Schmit, PhD, MPH, and was published in JAMA Network Open. It serves as an opportunity to better understand how immune checkpoint inhibitor treatments, including PD-1 and PD-L1 inhibitors, work in a larger population that reflects real-world settings. Dr. Schmit collaborated with a team of ...

Scientists use cellular programming to mimic first days of embryonic development

Scientists use cellular programming to mimic first days of embryonic development
2025-03-20
The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery.  The process of how a humble single cell becomes an organism fascinates scientists across disciplines. For some animals, the entire process of cellular multiplication, generation of specialized cells, and their organization into an ordered multicellular embryo takes place in the protective environment of the uterus, making direct observation and studies challenging. This makes it difficult for scientists to understand what can go wrong during that process, and how specific risk factors and the surrounding environment may prevent ...

Potential targeted therapy for pediatric brain cancer identified by Dana-Farber team

2025-03-20
Boston – An international team of clinical collaborators, led by physician scientists from Dana-Farber Cancer Institute, performed a first-ever clinical test of the targeted therapy avapritinib in pediatric and young patients with a form of high-grade glioma. They found that the drug, already FDA-approved for certain adult cancers, was generally safe and resulted in tumor reduction visible on brain scans, as well as clinical improvement, in 3 out of 7 patients. The study was published in Cancer Cell. Pediatric-type high-grade gliomas are currently incurable brain tumors with median survival times less than 18 months after initial diagnosis. Avapritinib ...

Self-assembled vesicles containing podophyllotoxin covalently modified with polyoxometalates for antitumor therapy

Self-assembled vesicles containing podophyllotoxin covalently modified with polyoxometalates for antitumor therapy
2025-03-20
POMs are a class of inorganic metal-oxygen cluster compounds with broad-spectrum antitumor potential. However, their strong hydrophilicity and poor lipophilicity result in insufficient cell membrane permeability, and high doses are required to achieve therapeutic effects, which severely limits their clinical application. To address this challenge, the research team proposes a covalent modification strategy: the construction of an amphipathic drug molecule PPT-POM-PPT by linking the hydrophobic anti-tumor drug Podophyllotoxin (PPT) with hydrophilic POMs. This molecule ...

Circadian rhythms in tumor regulation: Impacts on tumor progression and the immune microenvironment

Circadian rhythms in tumor regulation: Impacts on tumor progression and the immune microenvironment
2025-03-20
Circadian rhythms are endogenous time-keeping mechanisms that regulate physiological processes in response to external light-dark cycles. These rhythms are orchestrated by the suprachiasmatic nucleus (SCN) in the hypothalamus and involve a network of genes, including CLOCK and BMAL1, that influence metabolism, immune responses, and cell proliferation. Recent research has highlighted the crucial role of circadian rhythms in tumor biology, demonstrating that their dysregulation contributes to tumorigenesis, progression, and metastasis. Additionally, circadian rhythms influence the tumor immune microenvironment and the ...

The emerging role of flavonoids in the treatment of type 2 diabetes mellitus: regulating the enteroendocrine system

2025-03-20
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder with a rapidly increasing global prevalence. It is primarily characterized by insulin resistance, β-cell dysfunction, and impaired glucose homeostasis. Emerging research suggests that flavonoids, a diverse group of plant-derived polyphenols, may offer therapeutic potential in managing T2DM. These compounds exert antidiabetic effects through multiple mechanisms, including improving insulin sensitivity, enhancing β-cell function, modulating ...

Improving patient experience for the millions who visit an ED annually

2025-03-20
INDIANAPOLIS -- A large scale study by researchers from the Regenstrief Institute and the Indiana University School of Medicine has found that patient pain upon arrival to the Emergency Department (ED) as well as the use of hallway beds and radiology studies in the ED are associated with patient experience, although not in the same ways. The study’s tens of thousands of observations including clinical and operational data revealed that regardless of how promptly or successfully pain was treated in the ED, the amount of pain the patient was in when they arrived was associated with patient experience ...

Recycled cements drive down emissions without slacking on strength

Recycled cements drive down emissions without slacking on strength
2025-03-20
Giving a second life to construction materials after demolition, engineers at the University of São Paulo and Princeton have developed an approach for recycling cement waste into a sustainable, low-carbon alternative that is comparable in performance to the industry standard. In addition to lowering the carbon intensity of the cement and concrete industry, the process could enable new uses for construction and demolition waste, of which concrete is a significant component. In 2018 in the United States, the total ...

Beyond the cure: Navigating hepatocellular risk and surveillance after hepatitis C eradication in the direct-acting antiviral era

Beyond the cure: Navigating hepatocellular risk and surveillance after hepatitis C eradication in the direct-acting antiviral era
2025-03-20
Hepatitis C virus (HCV) infection remains a major global health burden, affecting millions worldwide and contributing significantly to hepatocellular carcinoma (HCC) development. The introduction of direct-acting antivirals (DAAs) has revolutionized HCV treatment, achieving high rates of sustained virologic response (SVR) and reducing HCV-associated morbidity and mortality. Despite these advancements, the risk of HCC persists in certain populations, particularly those with pre-treatment cirrhosis or advanced fibrosis (F3). This review examines the ...

LAST 30 PRESS RELEASES:

Scientists show how to predict world’s deadly scorpion hotspots

ASU researchers to lead AAAS panel on water insecurity in the United States

ASU professor Anne Stone to present at AAAS Conference in Phoenix on ancient origins of modern disease

Proposals for exploring viruses and skin as the next experimental quantum frontiers share US$30,000 science award

ASU researchers showcase scalable tech solutions for older adults living alone with cognitive decline at AAAS 2026

Scientists identify smooth regional trends in fruit fly survival strategies

Antipathy toward snakes? Your parents likely talked you into that at an early age

Sylvester Cancer Tip Sheet for Feb. 2026

Online exposure to medical misinformation concentrated among older adults

Telehealth improves access to genetic services for adult survivors of childhood cancers

Outdated mortality benchmarks risk missing early signs of famine and delay recognizing mass starvation

Newly discovered bacterium converts carbon dioxide into chemicals using electricity

Flipping and reversing mini-proteins could improve disease treatment

Scientists reveal major hidden source of atmospheric nitrogen pollution in fragile lake basin

Biochar emerges as a powerful tool for soil carbon neutrality and climate mitigation

Tiny cell messengers show big promise for safer protein and gene delivery

AMS releases statement regarding the decision to rescind EPA’s 2009 Endangerment Finding

Parents’ alcohol and drug use influences their children’s consumption, research shows

Modular assembly of chiral nitrogen-bridged rings achieved by palladium-catalyzed diastereoselective and enantioselective cascade cyclization reactions

Promoting civic engagement

AMS Science Preview: Hurricane slowdown, school snow days

Deforestation in the Amazon raises the surface temperature by 3 °C during the dry season

Model more accurately maps the impact of frost on corn crops

How did humans develop sharp vision? Lab-grown retinas show likely answer

Sour grapes? Taste, experience of sour foods depends on individual consumer

At AAAS, professor Krystal Tsosie argues the future of science must be Indigenous-led

From the lab to the living room: Decoding Parkinson’s patients movements in the real world

Research advances in porous materials, as highlighted in the 2025 Nobel Prize in Chemistry

Sally C. Morton, executive vice president of ASU Knowledge Enterprise, presents a bold and practical framework for moving research from discovery to real-world impact

Biochemical parameters in patients with diabetic nephropathy versus individuals with diabetes alone, non-diabetic nephropathy, and healthy controls

[Press-News.org] Prevalence and severity of astigmatism in children after COVID-19
JAMA Ophthalmology