PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Alliance presents project cure CRC poster sessions at AACR Annual Meeting & awards new grants to accelerate progress

2025-04-23
(Press-News.org) At a time when cancer research is experiencing uncertainty and setbacks, the Colorectal Cancer Alliance (Alliance) is strengthening its commitment to its Project Cure CRC initiative because tomorrow can’t wait. Project Cure CRC funds cutting-edge colorectal cancer (CRC) research and aims to improve patient outcomes through its dynamic patient navigation portal, BlueHQ.org. As the leading nonprofit dedicated to ending the disease, the Alliance awarded three new grants from Project Cure CRC and is presenting two poster sessions at the American Association for Cancer Research (AACR) Annual Meeting 2025, April 25-30, in Chicago, IL. To date, the total Project Cure CRC investment in innovative colorectal cancer research is more than $11.2 million with 24 grants funded.

 

“Without research, there is no progress,” said Michael Sapienza, CEO of the Colorectal Cancer Alliance. “Project Cure CRC provides critically needed funding to explore high-risk, high-reward breakthroughs in treatments for colorectal cancer, which is the second leading cause of cancer death in the nation.” 

 

Project Cure CRC Poster Sessions at AACR:

Title: " Advancing Colorectal Cancer Research and Personalized Treatment through a CRC Platform Clinical Trial"
Summary: The CRC platform trial will establish a collaborative, data-driven framework to accelerate the translation of research into clinical application. By incorporating ongoing adjustments and emphasizing targeted therapies, the trial aligns with the Alliance’s mission to deliver impactful research and offer personalized, effective treatments to CRC patients with limited options under current care. 

Presenting Authors: Kim Newcomer, David Fenstermacher, Michael Sapienza

 

Title: "Advancing Precision Medicine in Colorectal Cancer through Innovative Research and Targeted Therapies"
Summary: The Alliance is committed to advancing precision medicine and addressing key gaps in CRC care, particularly for patients with treatment-resistant profiles. By funding high-impact research and fostering collaboration, Project Cure CRC aims to accelerate the development of personalized, effective treatments for CRC patients, transforming the landscape of colorectal cancer care through personalized treatments, faster access to therapies, and improved outcomes. 

Presenting Authors: Kim Newcomer, David Fenstermacher, Michael Sapienza

 

Recent Project Cure CRC Grants:

Recipients of the most recent Project Cure CRC grants include investigators from across the nation focusing on various topics in colorectal cancer:

Brandon Bordeau, Ph.D., University of Michigan - Antibody PROTAC Conjugates for the Treatment of Colorectal Cancer ($200,000)

Karin Pelka, Ph.D., The J. David Gladstone Institutes - Shattering the Immunotherapy Ceiling in Colorectal Cancer ($500,000)

Raul Mostoslavsky, M.D., Ph.D., Massachusetts General Hospital - Targeting Novel Drivers of Metastatic Disease in Colorectal Cancer ($200,000)

For more information on Project Cure CRC, to donate, or to submit a research proposal, please visit colorectalcancer.org/research.

 

About the Colorectal Cancer Alliance

The Colorectal Cancer Alliance empowers a nation of passionate and determined allies to prevent, treat, and overcome colorectal cancer in their lives and communities. Founded in 1999 and headquartered in Washington, D.C., the Alliance advocates for prevention through initiatives like LEAD FROM BEHIND, magnifies support with BlueHQ, and accelerates research through Project Cure CRC. We are the largest national nonprofit dedicated to colorectal cancer, and we exist to end this disease in our lifetime. For more information, visit colorectalcancer.org.  

 

END


ELSE PRESS RELEASES FROM THIS DATE:

Family dynamics shape body image differently across cultures

2025-04-23
Body appreciation differs between Middle-Eastern and Western societies, a new international study can reveal, highlighting how cultural and family influences shape body image and eating behaviours in young women. Led by Flinders University and published in the journal Body Image, the study surveyed over 850 women aged 18–25 in Australia and Lebanon, examining the roles that mothers and sisters play in shaping body dissatisfaction, body appreciation, and eating patterns. Lead author, registered psychologist and PhD candidate Melanie ...

Crystal clear design for high-performance flexible thermoelectric semiconductor

2025-04-23
QUT researchers have identified a new material which could be used as a flexible semiconductor in wearable devices by using a technique that focuses on the manipulation of spaces between atoms in crystals. In a study published in the prestigious journal Nature Communication (http://doi.org/10.1038/s41467-025-58104-x), the researchers used “vacancy engineering” to enhance the ability of an AgCu(Te, Se, S) semiconductor, which is an alloy made up of silver, copper, tellurium, selenium and sulphur, to convert body ...

Detecting lung cancer 4 months earlier at the GP using artificial intelligence

2025-04-22
GPs may soon be able to identify patients with an increased risk of lung cancer up to 4 months earlier than is currently the case. The GP should be able to simply identify patients during a consultation with an algorithm created by researchers at Amsterdam UMC based on the data of more than half a million patients. The results of the study were published today in the British Journal of General Practice. [doi-link: https://doi.org/10.3399/BJGP.2023.0489]  The algorithm looks at all medical information from general ...

Safer opioid supply improves health outcomes among people at high risk of overdose

2025-04-22
Toronto, ON, April 22, 2025 – Research from ICES and Unity Health Toronto shows that safer opioid supply programs and methadone both reduce opioid overdoses, healthcare utilization, and costs.  Safer opioid supply (SOS) programs provide pharmaceutical-grade opioids such as hydromorphone to people struggling with opioid use disorder. Prescribed opioid medications are a safer alternative to drugs found in the unregulated drug supply due to the potency and unpredictability of that supply.  “This is the first population-based study to compare SOS programs with opioid agonist treatment, and to explore ...

Micronanoplastics found in artery-clogging plaque in the neck

2025-04-22
Research Highlights A small study found that fatty buildup in the blood vessels of the neck (carotid arteries) may contain 50 times or more micronanoplastics — minuscule bits of plastic — compared to arteries free of plaque buildup. Plaque, the fatty deposits that can narrow the carotid artery, may cause a stroke.    People unknowingly eat and drink micronanoplastics from plastic waste broken down and collected in the soil and water supply. Researchers say there is currently no effective way to prevent exposure to micronanoplastics. Note: The study featured in this news release is a research abstract. Abstracts presented at the American ...

TOS statement on oral GLP-1s

2025-04-22
ROCKVILLE, MD-Advances in evidence-based obesity medications and treatment options are critical for the millions of individuals living with the chronic disease. The Obesity Society is encouraged by the development of new options that are effective, safe, and convenient for consumers.  Last week, results released for the ACHIEVE-1 Phase 3 clinical trial suggest that a new medication, Orforglipron, an oral small molecule glucagon-like peptide-1 (GLP-1) receptor agonist, taken once daily led to an average weight loss of 7.9% in individuals with diabetes and ...

Pulmonary fibrosis has no cure. Could a cancer drug hold the answer?

2025-04-22
Researchers at Tulane University have identified a potential new way to treat idiopathic pulmonary fibrosis (IPF), a deadly and currently incurable lung disease that affects more than 3 million people worldwide. IPF is rapidly progressive and causes scarring in the lungs, making it difficult to breathe. Approximately 50% of patients die within three years of diagnosis, and current treatments can only slow the disease — not stop or reverse it.  In a study published in the Journal ...

Trial explores drug-free approach to treat ADHD symptoms in children exposed to alcohol before birth

2025-04-22
Researchers at UCLA Health are launching the first clinical trial to test whether a wearable device that delivers gentle nerve stimulation during sleep could ease ADHD symptoms in children with prenatal alcohol exposure. Children exposed to alcohol in the womb have a heightened risk of developing ADHD-like symptoms including hyperactivity, impulsivity and executive function deficits such as difficulty paying attention, remembering, and organizing their behavior. Prenatal alcohol exposure affects about 5% of children in the U.S. with the majority developing these symptoms. ...

New research points out a promising strategy for treating metastatic medulloblastoma

2025-04-22
Researchers at Baylor College of Medicine, Texas Children’s Hospital, the Hospital for Sick Children in Toronto and collaborating institutions reveal in Nature Cell Biology a strategy that helps medulloblastoma, the most prevalent malignant brain tumor in children, spread and grow on the leptomeninges, the membranes surrounding the brain and spinal cord. They discovered a novel line of communication between metastatic medulloblastoma and leptomeningeal fibroblasts that mediates recruitment and reprogramming of the latter to support tumor growth. The findings suggest that disrupting this communication offers a potential opportunity to treat this devastating ...

Light fields with extraordinary structure: plasmonic skyrmion bags

2025-04-22
“Our results add another chapter to the emerging field of skyrmion research,” proclaims Prof. Harald Giessen, head of the Fourth Physics Institute at the University of Stuttgart, whose group achieved this breakthrough. The team demonstrated the existence of “skyrmion bags” of light on the surface of a metal layer. A better understanding of physical phenomena Skyrmions are a mathematical description of vortex-like structures that help researchers better understand fundamental physical relationships. In recent years, this theoretical ...

LAST 30 PRESS RELEASES:

KIMM launches initiative to establish a regional hub for mechanical researcher in Asia

AMI warns that the threat of antimicrobial resistance in viruses and other pathogens cannot be underestimated

As ‘California sober’ catches on, study suggests cannabis use reduces short-term alcohol consumption

Working with local communities to manage green spaces could help biodiversity crisis, new study finds

Parental monitoring is linked to fewer teen conduct problems despite genetic risk

From stadiums to cyberspace: How the metaverse will redefine sports fandom 

The hidden rule behind ignition — An analytic law governing multi-shock implosions for ultrahigh compression

Can AI help us predict earthquakes?

Teaching models to cope with messy medical data

Significant interest in vegan pet diets revealed by largest surveys to date

A new method for the synthesis of giant fullerenes

National team works to curb costly infrastructure corrosion

A ‘magic bullet’ for polycystic kidney disease in the making

Biochar boosts clean energy output from food waste in novel two-stage digestion system

Seismic sensors used to identify types of aircraft flying over Alaska

The Lancet: Experts warn global rise in ultra-processed foods poses major public health threat; call for worldwide policy reform

Health impacts of eating disorders complex and long-lasting

Ape ancestors and Neanderthals likely kissed, new analysis finds

Ancient bogs reveal 15,000-year climate secret, say scientists

Study shows investing in engaging healthcare teams is essential for improving patient experience

New pika research finds troubling signs for the iconic Rocky Mountain animal

Seismic data can identify aircraft by type

Just cutting down doesn’t cut it when it comes to the impact of smoking on your health

Gene silencing may slow down bladder cancer

Most people with a genetic condition that causes significantly high cholesterol go undiagnosed, Mayo Clinic study finds

The importance of standardized international scores for intensive care

Almost half of Oregon elk population carries advantageous genetic variant against CWD, study shows

Colorectal cancer screenings remain low for people ages 45 to 49 despite guideline change

Artificial Intelligence may help save lives in ICUs

Uncovering how cells build tissues and organs

[Press-News.org] Alliance presents project cure CRC poster sessions at AACR Annual Meeting & awards new grants to accelerate progress