PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Cognitive and functional decline among long-term care residents

JAMA Network Open

2025-04-23
(Press-News.org)

About The Study: In this study, severe permanent impairment in function and cognition were common and often present near the end of life for long-term care residents, but a minority of residents lived in these states for years. These results suggest that building shared understanding and open communication about the natural course of frailty trajectories for long-term care residents may support resident-centered medical decision-making.

Corresponding Author: To contact the corresponding author, Daniel Kobewka, MD, MSc, email dkobewka@toh.ca.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2025.5635)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.5635?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042325

END



ELSE PRESS RELEASES FROM THIS DATE:

Screening and response for adverse social determinants of health in US emergency departments

2025-04-23
About The Study: Despite the high prevalence of adverse social determinants of health (SDOH) in emergency department (ED) populations, in this survey study of 232 EDs, less than one-third performed screening, and one-fifth did not have policies requiring a response to positive screens. Bridging this gap may require expanding adverse SDOH screening practices while also ensuring that EDs have the resources and infrastructure to respond appropriately to identified social needs. Future research might explore advanced technological solutions ...

How DNA self-organizes in the early embryo

2025-04-23
Early DNA Organization is Robust and Flexible When the egg and sperm fuse, a comprehensive reorganization of DNA begins within the nucleus. Epigenetics plays a crucial role in this process, regulating gene activity through chemical modifications on DNA and its associated proteins. “We wanted to understand how these epigenetic programs influence gene activity and ensure that the cell correctly executes its developmental tasks,” explains study leader Prof. Maria-Elena Torres-Padilla, Director at the Institute of Epigenetics ...

Remembering the cold: scientists discover how memories control metabolism

2025-04-23
New multidisciplinary research led by Prof. Tomás Ryan from Trinity College Dublin shows that the brain forms memories of cold experiences and uses them to control our metabolism. This newly published study is the first to show that cold memories form in the brain – and map out how they subsequently drive thermoregulation. The discovery may have important applications in therapies designed to treat a range of disorders – from obesity to cancer – in which thermoregulation and metabolism (or a lack of control in this area) plays a role, as ...

Phoenician culture spread mainly through cultural exchange

2025-04-23
To the point Secret of the Phoenician-Punic civilization's success: Their culture spread across the Mediterranean not through large-scale mass migration, but through a dynamic process of cultural transmission and assimilation. Melting pot of ancient people: The study found that Punic populations had a highly variable and heterogeneous genetic profile, with significant North African and Sicilian-Aegean ancestry. Highly interconnected: Ancient Mediterranean societies were cosmopolitan, with people from different regions trading, moving often over large distances and having offspring with each other. This provides new insights into the region's cultural and population history in ...

Smoking cessation drug varenicline helps young adults quit vaping

2025-04-23
A new study by investigators from Mass General Brigham showed that teens and young adults who took varenicline—an FDA-approved, twice-daily smoking cessation pill for adults—are more than three times as likely to successfully quit vaping compared to those who received only behavioral counseling. Results are published in JAMA. “Vaping is extremely popular among kids, and we know that this early nicotine exposure can make drugs like cocaine more addictive down the line, yet ours is the first ...

How bacteria in our aging guts can elevate risk of leukemia and perhaps more

2025-04-23
CINCINNATI—Scientists at Cincinnati Children’s along with an international team of researchers have discovered a surprising new connection between gut health and blood cancer risk—one that could transform how we think about aging, inflammation, and the early stages of leukemia. As we grow older—or in some cases, when gut health is compromised by disease—changes in the intestinal lining allow certain bacteria to leak their byproducts into the bloodstream. One such molecule, produced by specific bacteria, acts as a signal that accelerates the expansion of dormant, pre-leukemic blood cells, a critical step ...

Four generations help science explore genome mutation rate

2025-04-23
An advanced genomic analysis of a multigenerational family is providing new knowledge about genetic mutations and their transmission, both the variants that are inherited and those that arise anew. The findings are published today, April 23, in Nature.  “We sequenced and assembled the chromosomes of multiple members of a large, four-generation family to understand how the genetic information changed from generation to generation,” said Evan E Eichler, professor of genome sciences at the University of Washington School of Medicine in Seattle and the corresponding author of the paper. During the study, lead author David Porubsky was a postdoctoral fellow at the UW. Porubsky ...

Mathematician and biochemist win transdisciplinary research prize

2025-04-23
The Transdisciplinary Research Areas (TRAs) Modelling and Life and Health at the University of Bonn have presented their €100,000 research prize, entitled “Modelling for Life and Health,” for the second time. The winners—Argelander Professor Ana Ivonne Vazquez-Armendariz and Schlegel Professor Jan Hasenauer—will be using their prize money to study the functions of “scavenger cells” in the lungs at the interface between mathematics and medicine. The lung’s very own scavenger cells, known as alveolar macrophages, ...

U.S. Dementia costs to exceed $780 billion this year

2025-04-23
The total economic burden of Alzheimer’s disease and related dementias in the United States will reach $781 billion this year, according to new USC-led research. This is the first of what will be annual national estimates from the multidisciplinary research team. The team aims to provide the most comprehensive accounting yet of dementia’s growing economic toll. Beyond the cost of care, the model also accounts for lost earnings from patients and care partners who cut back work hours or leave jobs, ...

Childhood exposure to bacterial toxin may be triggering colorectal cancer epidemic among the young

2025-04-23
In an effort to explain a modern medical mystery, an international team of researchers led by the University of California San Diego has identified a potential microbial culprit behind the alarming rise in early-onset colorectal cancer: a bacterial toxin called colibactin. Produced by certain strains of Escherichia coli that reside in the colon and rectum, colibactin is a toxin capable of altering DNA. Now, scientists report that exposure to colibactin in early childhood imprints a distinct genetic signature on the DNA of colon cells—one that may ...

LAST 30 PRESS RELEASES:

Breathable yet protective: Next-gen medical textiles with micro/nano networks

Frequency-engineered MXene supercapacitors enable efficient pulse charging in TENG–SC hybrid systems

Developed an AI-based classification system for facial pigmented lesions

Achieving 20% efficiency in halogen-free organic solar cells via isomeric additive-mediated sequential processing

New book Terraglossia reclaims language, Country and culture

The most effective diabetes drugs don't reach enough patients yet

Breast cancer risk in younger women may be influenced by hormone therapy

Strategies for staying smoke-free after rehab

Commentary questions the potential benefit of levothyroxine treatment of mild hypothyroidism during pregnancy

Study projects over 14 million preventable deaths by 2030 if USAID defunding continues

New study reveals 33% gap in transplant access for UK’s poorest children

Dysregulated epigenetic memory in early embryos offers new clues to the inheritance of polycystic ovary syndrome (PCOS)

IVF and IUI pregnancy rates remain stable across Europe, despite an increasing uptake of single embryo transfer

It takes a village: Chimpanzee babies do better when their moms have social connections

From lab to market: how renewable polymers could transform medicine

Striking increase in obesity observed among youth between 2011 and 2023

No evidence that medications trigger microscopic colitis in older adults

NYUAD researchers find link between brain growth and mental health disorders

Aging-related inflammation is not universal across human populations, new study finds

University of Oregon to create national children’s mental health center with $11 million federal grant

Rare achievement: UTA undergrad publishes research

Fact or fiction? The ADHD info dilemma

Genetic ancestry linked to risk of severe dengue

Genomes reveal the Norwegian lemming as one of the youngest mammal species

Early birds get the burn: Monash study finds early bedtimes associated with more physical activity

Groundbreaking analysis provides day-by-day insight into prehistoric plankton’s capacity for change

Southern Ocean saltier, hotter and losing ice fast as decades-long trend unexpectedly reverses

Human fishing reshaped Caribbean reef food webs, 7000-year old exposed fossilized reefs reveal

Killer whales, kind gestures: Orcas offer food to humans in the wild

Hurricane ecology research reveals critical vulnerabilities of coastal ecosystems

[Press-News.org] Cognitive and functional decline among long-term care residents
JAMA Network Open