PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Rise in expectant mothers in UK with autoimmune diseases since millennium

MuM-PreDiCT project found that some conditions are on rise in pregnant women, requiring a better understanding of managing these diseases during maternity

2025-06-02
(Press-News.org) Thousands more UK women who are having children have been diagnosed with an autoimmune condition now compared to the beginning of the millennium.

In a paper published in Lancet Rheumatology today, researchers involved in the MuM-PreDiCT project run by the University of Birmingham and funded by the Medical Research Council have found that there has been increase by 4.7% in expectant mothers beginning pregnancy with autoimmune conditions.

Analysis of electronic healthcare records (CPRD) taken from 2000-2021 found that there was a rise in conditions diagnosed pre-pregnancy in women aged 15-49 including psoriasis, coeliac disease and type 1 diabetes mellitus as well as rarer conditions such as Grave’s disease and Hashimoto thyroiditis.

Dr Megha Singh from the University of Birmingham and lead author of the study said:

“This is the first time that this kind of study has been done, showing that there is a rise in autoimmune conditions in women that are becoming pregnant. We looked at a wide range of autoimmune conditions, unlike any study previously carried out, and we know that these conditions by and large affect women and previous studies have shown that there is an increase overall in autoimmune conditions. As a result, these findings are not surprising, but are crucial for public health.

“Our project is all about understanding how to support women during pregnancy who are managing medical conditions, often co-morbidly, and this data gives us a much better idea about the scale of autoimmune conditions for expectant mums.”

Further analysis of the data for factors of deprivation, ethnicity and other factors shows that the least deprived areas saw a 10% rise in pre-pregnancy autoimmune condition diagnosis, and ethnic minority groups of women had lower incidence rates compared to white women. However, some conditions such as psoriasis were more prevalent among deprived areas and among some ethnic minority groups.

Dr Francesca Crowe, senior author, from the University of Birmingham of the paper said:

“There are likely to be a combination of factors driving the increase in autoimmune condition diagnoses before pregnancy, including different factors among groups of people. An awareness of conditions and differential access to healthcare may be involved, and it is very likely therefore that the numbers we are seeing under reports the real scale of women’s health in pregnancy.”

Prof Krish Nirantharakumar, corresponding and co-author from King’s College London said: “This important study will aid clinicians and policy makers to redefine existing care- pathways and plan future health services for pregnant women with autoimmune conditions to achieve better outcomes for mums and their babies”

END


ELSE PRESS RELEASES FROM THIS DATE:

Majority of riders and drivers in UK 'gig economy' suffer anxiety over ratings and pay, study suggests

2025-06-02
Some two-thirds of riders and drivers for food delivery and ride-hailing apps in the UK may work in fear of “unfair feedback” and experience anxiety over sudden changes to working hours, a new survey study led by the University of Cambridge suggests.* Three-quarters of riders and drivers in the study report anxiety over potential for income to drop, with over half (51%) saying they risk health and safety while working. Some 42% of delivery and driver gig workers say they suffer physical pain resulting from work. Riders ...

Virginia Tech researchers develop recyclable, healable electronics

2025-06-02
Between upgrades and breakdowns to cellphones, tablets, laptops, and appliances, so many electronics are getting tossed in the trash that they've taken on a name of their own: e-waste. According to a 2024 report issued by the United Nations, the amount of e-waste worldwide has almost doubled in the past 12 years, from 34 billion to 62 billion kilograms — the equivalent of 1.55 million shipping trucks — and it's estimated to hit 82 billion kilograms by 2030. Just 13.8 billion kilograms — about 20 percent of the total — is expected to be recycled, a number ...

Cognitive outcomes similar after noncardiac surgery whether perioperative hypotension- or hypertension-avoidance strategies employed

2025-06-02
Embargoed for release until 5:00 p.m. ET on Monday 2 June 2025    Follow @Annalsofim on X, Facebook, Instagram, threads, and Linkedin         Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the embargo not only on their own behalf, but also on behalf of the organization they represent.    ----------------------------       Cognitive ...

Research spotlight: regional disparities in opioid overdose mortality persist despite national decline

2025-06-02
Sarah Wakeman, MD, Senior Medical Director for Substance Use Disorder at Mass General Brigham, is the co-senior author and Will Oles, BS, of Harvard Medical School, is a corresponding author of a paper published in the Journal of General Internal Medicine, “Geographic Trends in Opioid and Polysubstance Overdose Deaths in the US, 2014-2023.”  Q: How would you summarize your study for a lay audience?  In May 2024, the Centers for Disease Control (CDC) announced a national decline in the ...

Fighting myeloma with fiber: Plant-based diet offers promise

2025-06-02
Results from a new clinical trial suggest that a high-fiber plant-based diet could benefit patients at risk for developing multiple myeloma, the second most common type of blood cancer. The study showed that the diet was not only feasible and well-received but also improved several factors that could potentially delay the progression of precancerous conditions that can lead to multiple myeloma.     Multiple myeloma is often preceded by early, non-cancerous conditions involving abnormal plasma cells, a type of white blood cell found in the bone marrow. Having a high body weight, ...

What makes someone leave a Medicare Advantage plan?

2025-06-02
More than half of older Americans now get their Medicare coverage through an insurance company’s Medicare Advantage plan. But many go on to switch plans or even leave for traditional Medicare when Open Enrollment comes around each autumn. Researchers have had a hard time getting access to data that could help them understand what drives these changes, which have major implications for federal spending on Medicare as well as individuals’ health. Now, a new study in the June issue of Health Affairs peels back the curtain on what motivates people to switch ...

ASCO: New antibody-drug conjugate shows promising safety and response rates for patients with rare blood cancer

2025-06-02
Blastic plasmacytoid dendric cell neoplasm (BPDCN) is a rare, aggressive blood cancer that often involves the bone marrow, skin and, sometimes, lymph nodes. First-in-class antibody-drug conjugate, pivekimab sunirine (PVEK), was safe and effective. PVEK achieved an overall response rate of 85% and complete response rate of 70% as frontline treatment in newly diagnosed patients with BPDCN. Findings suggest this treatment should be considered as a new standard of care for these patients. ABSTRACT: 6502  CHICAGO, JUNE 2, 2025 ― The first-in-class ...

Advancing personalized medicine through pharmacogenomics: Insights from Ochsner Health

2025-06-02
In a report recently published in the American Journal of Health-System Pharmacy, the Ochsner Health system delves into the multifaceted implementation of pharmacogenomics—a rapidly evolving field that examines how genetics influence individual responses to medication. This comprehensive article, led by Dr. Catherine Oliver and a team of experts in pharmacy services, provides an insightful blueprint for health systems aiming to integrate pharmacogenomics into clinical practice.  "Pharmacogenomics embodies a new frontier in precision medicine, enabling us to fine-tune treatments ...

Researchers tested an asthma drug for treating alcoholism. It failed except with this group

2025-06-02
Key takeaways Ibudilast is a drug approved in Japan for the treatment of asthma and post-stroke dizziness by targeting inflammation; previous research suggested it could also help people reduce their drinking.  A UCLA clinical trial, however, has now shown that ibudilast worked no better than a placebo for trial participants in reducing alcohol consumption, although it did have a positive effect on women. Women tend to have higher levels of inflammation than men, and the results of ibudilast testing with women point toward ...

Set it and forget it: Autonomous structures can be programmed to jump days in advance

2025-06-02
Researchers have created dynamic structures that leap into the air on a predetermined schedule without intervention from computers or external stimuli. Precisely when these “metashells” jump, and how high they jump, is engineered into the physical structure of the materials. “There are structures that ‘jump’ immediately when loading is removed – such as when a coiled spring is released,” says Jie Yin, corresponding author of a paper on the work and an associate professor of mechanical engineering at North Carolina State University. “We wanted to create a structure that does not rely on external stimuli and allows us to dictate the timing ...

LAST 30 PRESS RELEASES:

Studying the 12C+12C fusion reaction at astrophysical energies using HOPG target

Bacteria hitch a ride on yeast puddles to zoom around

New non-invasive method discovered to enhance brain waste clearance

A summer like no other: inside 2023’s record-smashing North Atlantic marine heatwave

Many possible futures: How dopamine in the brain might inform AI that adapts quickly to change

Research shows rivers release ancient carbon dioxide into the atmosphere, uncovering a greater role for plants and soil in the carbon cycle

Hypertension, diabetes, and high cholesterol awareness among US adults

Longitudinal outcomes of the COVID-19 pandemic on youth physical fitness

Study shows loss of Y in blood cells hinders immune response to cancer

Loss of Y chromosome leads to poor cancer outcomes

The atmosphere’s growing thirst is making droughts worse, even where it rains

Colorectal cancer leaves lasting toll on women’s sexual health

New technology developed at the Lewis Katz School of Medicine at Temple University promises faster, earlier diagnosis of deadly form of heart failure

PolyU scholar honored with the Hong Kong Engineering Science and Technology Award for contributions to Web3 and digital economy

Nationwide study finds that leaks in natural gas pipelines contribute to hazardous particulate air pollution

‘Eye’ on health: AI detects dizziness and balance disorders remotely

EyeCare4Kids™ names Maggie Cline as new CEO

Moderate exercise slows brain aging: U-shaped association revealed by accelerometry

Bat viruses similar to MERS have potential to jump to humans

New 3D-printing method makes two materials from one resin

A better understanding of how gene editing tools work

Tool for protecting soldiers’ brain health earns $3.2 million grant

Virginia Tech researcher earns American Heart Association fellowship to explore how obesity increases the risk for heart disease

Study identifies personality traits associated with bedtime procrastination

How late college students go to sleep is influenced by the need to belong

Discovery of giant planet orbiting tiny star challenges theories on planet formation

Blood sugar response to various carbohydrates can point to metabolic health subtypes, study finds

Why AI can’t understand a flower the way humans do

Top scientists call for permanent ban on high seas exploitation

A new blood-based epigenetic clock for aging focuses on intrinsic capacity

[Press-News.org] Rise in expectant mothers in UK with autoimmune diseases since millennium
MuM-PreDiCT project found that some conditions are on rise in pregnant women, requiring a better understanding of managing these diseases during maternity