Prediction of optic disc edema progression during spaceflight

JAMA Ophthalmology

2025-11-20

(Press-News.org) About The Study: The findings of this study suggest crewmembers who did not develop optic disc edema (ODE) on flight day 30 were unlikely to develop clinically concerning ODE on flight day 150. The data suggest that optical coherence tomography imaging during spaceflight missions provides an opportunity to predict the magnitude of ODE that may develop during a longer-lasting mission.

Corresponding Author: To contact the corresponding author, Brandon R. Macias, PhD, email brandon.r.macias@nasa.gov.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaophthalmol.2025.4635)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Prediction of optic disc edema progression during spaceflight

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