(Press-News.org) About The Study: In this cohort study, the use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) among patients with diabetes was associated with a 2-fold higher risk of incident neovascular age-related macular degeneration development than among similar patients with diabetes who did not receive a GLP-1 RA. Further research is needed to elucidate the exact pathophysiological mechanisms involved and to understand the trade-offs between the benefits and risks of GLP-1 RAs.
Corresponding Author: To contact the corresponding author, Rajeev H. Muni, MD, MSc, email rajeev.muni@utoronto.ca.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamaophthalmol.2025.1455)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaophthalmology/fullarticle/10.1001/jamaophthalmol.2025.1455?guestAccessKey=6090e38f-93ad-448f-aaff-ef4768286c5d&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=060525
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Glucagon-like peptide-1 receptor agonists and risk of neovascular age-related macular degeneration
JAMA Ophthalmology
2025-06-05
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[Press-News.org] Glucagon-like peptide-1 receptor agonists and risk of neovascular age-related macular degenerationJAMA Ophthalmology