Glucagon-like peptide-1 receptor agonists and risk of neovascular age-related macular degeneration

JAMA Ophthalmology

2025-06-05

(Press-News.org) About The Study: In this cohort study, the use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) among patients with diabetes was associated with a 2-fold higher risk of incident neovascular age-related macular degeneration development than among similar patients with diabetes who did not receive a GLP-1 RA. Further research is needed to elucidate the exact pathophysiological mechanisms involved and to understand the trade-offs between the benefits and risks of GLP-1 RAs.

Corresponding Author: To contact the corresponding author, Rajeev H. Muni, MD, MSc, email rajeev.muni@utoronto.ca.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaophthalmol.2025.1455)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaophthalmology/fullarticle/10.1001/jamaophthalmol.2025.1455?guestAccessKey=6090e38f-93ad-448f-aaff-ef4768286c5d&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=060525

END

ELSE PRESS RELEASES FROM THIS DATE:

BMI, physical activity, and subsequent neoplasm risk among childhood cancer survivors

2025-06-05

About The Study: Among childhood cancer survivors in this cohort study, obesity was associated with an increased risk for multiple subsequent neoplasm types, while higher physical activity was associated with reduced subsequent neoplasm risk. Lifestyle interventions should be considered in future subsequent neoplasm prevention research. Corresponding Author: To contact the corresponding author, Lenat Joffe, MD, MS, email ljoffe@northwell.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamaoncol.2025.1340) Editor’s Note: Please see the article for additional ...

Chimpanzees can catch yawns from androids

2025-06-05

Chimpanzees (Pan troglodytes) can ‘catch’ yawns from an android imitating human facial expressions, according to new research from City St George’s, University of London. The study, published in Scientific Reports, demonstrates that chimpanzees will both yawn and lie down in response to yawns made by an android, suggesting that it may act as a cue to rest rather than simply triggering an automatic response. The findings appear to show contagious yawning due to an inanimate model for the first time, according to the authors, and the study also ...

The Holberg Prize conferred upon Professor Gayatri Chakravorty Spivak

2025-06-05

At a prestigious award ceremony today in the University Aula in Bergen, Gayatri Chakravorty Spivak received the international research award from HRH Crown Prince Haakon of Norway. Spivak is University Professor in the Humanities at Columbia University. The Holberg Prize is worth NOK 6 million (approx. USD 600,000) and is awarded annually for outstanding contributions to research in the humanities, social sciences, law or theology. Expressing her deepest gratitude as well as her surprise on receiving the award, Spivak accepted the Holberg ...

Up and running—first room-temperature quantum accelerator of its kind in Europe

2025-06-05

To further accelerate its pioneering research in the field of quantum computing, the Fraunhofer Institute for Applied Solid State Physics IAF is expanding its unique quantum computing infrastructure with the latest system from Quantum Brilliance (QB). Following a public tender, the Quantum Development Kit (QB-QDK2.0) is operational and integrated directly into the high-performance computing infrastructure at Fraunhofer IAF. The system requires no cryogenics, fits into a standard 19” server rack, and enables energy-efficient, hybrid quantum-classical computing in conventional IT environments. ...

Using swarm intelligence to improve treatment of acute stroke

2025-06-05

Researchers at DZNE and the Department of Vascular Neurology at the University Hospital Bonn (UKB) aim to develop a computer model based on artificial intelligence (AI) to aid doctors in treating stroke patients. Serving as a digital assistance system, it is intended to predict the long-term outcome of patients after a minimally invasive treatment (mechanical thrombectomy) and potential complications, thereby helping doctors decide on the best possible therapy. A proof-of-concept study will now be undertaken to determine whether this is feasible using data from the “German Stroke Registry” and additional brain images. The project relies on an AI technology called “Swarm ...

Weight stigma—not BMI—has the biggest effect on mental health after weight-loss surgery

2025-06-05

New research shows that weight stigma—and not weight itself—has the biggest impact on mental health and healthy behaviors in the years after weight-loss surgery. Researchers found that patients who had gone through weight-loss surgery tended to experience much less weight stigma, and that this reduction in weight stigma—but not lower BMI—was associated with healthier eating habits and better mental health. On the other hand, continuing to experience stigma after surgery was associated with higher risks of ...

Research alert: Alzheimer's gene therapy shows promise in preserving cognitive function

2025-06-05

Researchers at University of California San Diego School of Medicine have developed a gene therapy for Alzheimer’s disease that could help protect the brain from damage and preserve cognitive function. Unlike existing treatments for Alzheimer’s that target unhealthy protein deposits in the brain, the new approach could help address the root cause of Alzheimer’s disease by influencing the behavior of brain cells themselves. Alzheimer's disease affects millions of people around the world and occurs when abnormal ...

New York Eye and Ear Infirmary of Mount Sinai opens first Comprehensive Center for Refractive Solutions in New York

2025-06-05

New York Eye and Ear Infirmary of Mount Sinai (NYEE) has announced the opening of the Center for Refractive Solutions—the first in New York City and one of few in the United States—that offers comprehensive and innovative treatment options for those who require refractive correction. This includes premium cataract and intraocular lens surgery, and corneal refractive procedures such as LASIK, to reduce patients’ dependency on glasses and contact lenses. The newly renovated space, located at 310 East 14th Street in Lower Manhattan, is solely dedicated ...

Storm ready: FAU Sensing Institute’s weather network delivers real-time forecasting

2025-06-05

As Floridians prepare for an active 2025 Atlantic hurricane season, the most serious threat may not come from wind, but from water. Data from the National Hurricane Center shows that 86% of all direct hurricane and tropical storm fatalities in the United States between 2013 and 2023 were caused by water impacts – freshwater flooding, storm surge and rip currents. Of those, more than half resulted from drownings due to inland flooding, highlighting the critical importance of accurate rainfall and flood forecasting. Florida Atlantic University’s Sensing Institute (I-SENSE) has emerged as a vital contributor to the nation’s ...

UChicago receives $21 million to establish visionary center in quantum engineering and health

2025-06-05

A $21 million gift from philanthropist Thea Berggren to the University of Chicago will establish the Berggren Center for Quantum Biology and Medicine, launching a bold scientific field that merges quantum technology with biology to transform the future of medicine. This pioneering, interdisciplinary effort seeks to harness the power of quantum engineering — capable of the most sensitive measurements known to science — to peer inside the human body in unprecedented ways. The goal is to unlock insights into biology and disease that were previously out of reach, ...

Glucagon-like peptide-1 receptor agonists and risk of neovascular age-related macular degeneration

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: