Role of sleep and white matter in the link between screen time and depression in childhood and early adolescence
JAMA Pediatrics
2025-06-23
(Press-News.org) About The Study: The results of this study show that more screen time in late childhood was associated with more depressive symptoms, potentially due to shorter sleep and worse white matter organization during early adolescence. These findings emphasize the importance of promoting healthy habits and balancing screen time with adequate sleep.
Corresponding Author: To contact the corresponding author, João Paulo Lima Santos, MD, email limasantosjp2@upmc.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamapediatrics.2025.1718)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2025.1718?guestAccessKey=1be1d75a-9127-47d8-97f3-923e64d763fa&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=062325
END
ELSE PRESS RELEASES FROM THIS DATE:
2025-06-23
About The Study: U.S. neonatal mortality has generally decreased, likely due to medical advancements, improved prenatal care, and neonatal intensive care interventions. However, mortality from slow fetal growth and malnutrition has increased by nearly 2% annually, possibly reflecting impaired prenatal nutrition.
Corresponding Author: To contact the corresponding author, Muzamil Khan, MD, email muzamilkhan1411@gmail.com.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamapediatrics.2025.1710)
Editor’s ...
2025-06-23
For the first time, scientists using cryo-electron microscopy have discovered the structure and shape of key receptors connecting neurons in the brain’s cerebellum, which is located behind the brainstem and plays a critical role in functions such as coordinating movement, balance and cognition.
The research, published today in the journal Nature, provides new insight that could lead to the development of therapies to repair these structures when they are disrupted either by injury or genetic mutations affecting motor skills -- sitting, standing, walking, running, and jumping -- learning and memory.
The discovery by scientists at Oregon Health ...
2025-06-23
PITTSBURGH, June 23, 2025 – In this digital era, both kids and adults are often glued to smartphone screens. Digital technology keeps users entertained, connected to friends, and in tune with important news. But some reports suggest that, particularly for adolescents, excessive time on these screens can be linked to mental health problems and even depression.
New research from the University of Pittsburgh School of Medicine published today in JAMA Pediatrics suggests that that association is driven by shorter ...
2025-06-23
A rare gene mutation that delays Alzheimer’s disease does so by damping inflammatory signaling in brain-resident immune cells, according to a preclinical study led by investigators at Weill Cornell Medicine. The finding adds to growing evidence that brain inflammation is a major driver of neurodegenerative disorders such as Alzheimer’s—and that it may be a key therapeutic target for these disorders.
In the study, published June 23 in Immunity, the researchers examined the effects of the mutation APOE3-R136S—known as the “Christchurch ...
2025-06-23
Researchers at the Center for Medicinal Cannabis Research at University of California San Diego School of Medicine have found that cannabidiol (CBD), a non-intoxicating compound found in cannabis, could help reduce problematic behaviors in autistic boys. The results provide valuable insights into the potential benefits and limitations of CBD as a therapeutic intervention for autism.
Autism spectrum disorder is a complex neurodevelopmental condition characterized by social communication difficulties, repetitive behaviors ...
2025-06-23
CAR-T cells, which are genetically programmed to specifically recognize and kill target cells, have altered the therapeutic landscape of lymphoma. After the tumor antigens are identified by scFv, CAR-T cells execute anti-tumor activity through granzyme and perforin secretion, inducing cell apoptosis in a Fas-FasL-dependent pathway and producing inflammatory cytokines to antagonize the immunosuppressive tumor microenvironments (TME) and induce host immune responses. However, CAR-T cell therapy still faces many challenges owing to the heterogeneity of tumor cells, interference from TME, T cell exhaustion, as well as severe adverse events. Recent years, advances in tumor ...
2025-06-23
Tsukuba, Japan—Displaced aggression, such as lashing out at an unrelated individual after a frustrating experience, is a well-documented phenomenon in both humans and animals. In mice, males typically attack unfamiliar, potentially rival males that enter their territory. However, when the rival was placed inside a transparent enclosure, physical contact was blocked despite visual and olfactory access. This situation increased arousal in the subject—a phenomenon known as "social instigation"—which primed the animal for heightened aggression. When subsequently presented with access to a different rival, the subject exhibited significantly ...
2025-06-23
1. Prediction of key genes in the AICAR biosynthetic pathway of endophytic Fusarium solani
Previous study showed that overexpression of the global regulator VeA mediated a significant increase in the antitumor activity of F. solani, with a marked enrichment of differential metabolites including AICAR. To elucidate the molecular regulatory mechanism by which veAOE14 contributed to the increased synthesis of AICAR, we obtained the predicted synthetic pathway of AICAR in F. solani by analyzing the veAOE14 transcriptome and metabolome data, with a total of 10 steps in the major synthetic reactions. Based on the previous findings and predicted ...
2025-06-23
A low FODMAP diet developed by Monash University researchers for irritable bowel syndrome (IBS) has been shown to improve gastrointestinal symptoms in women with endometriosis.
Sixty percent of study participants responded to the Low FODMAP Diet (LFD), compared to 26 per cent who responded to a control diet based on Australian Dietary Guidelines.
The majority of those on the LFD experienced a clinically significant improvement in gastrointestinal symptoms, and overall symptom severity was 40 per cent lower on the LFD than on the control diet.
Published in Alimentary Pharmacology and Therapeutics, researchers found that the LFD also eased abdominal pain and bloating, and normalised ...
2025-06-23
(Santa Barbara, Calif.) — A condition long considered to be unfavorable to electrical conduction in semiconductor materials may actually be beneficial in 2D semiconductors, according to new findings by UC Santa Barbara researchers published in the journal Physical Review Letters.
Electron-phonon interactions — collisions between charge-carrying electrons and heat-carrying vibrations in the atomic lattice of the material — are considered the primary cause of electrons slowing down as they travel through semiconductor material. But according to UCSB mechanical engineers Bolin Liao and Yujie Quan, when electrons ...
LAST 30 PRESS RELEASES:
[Press-News.org] Role of sleep and white matter in the link between screen time and depression in childhood and early adolescence
JAMA Pediatrics