PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Technical refinement in airway surgery: Wrapping tracheobronchial anastomoses

2025-06-25
(Press-News.org)

In this April 2025 issue of Translational Lung Cancer Research, a pioneering study, led by Professor Shuben Li from the First Affiliated Hospital of Guangzhou Medical University, revisits a classic but unresolved question in airway surgery: Should tracheobronchial anastomoses be routinely wrapped following resection and reconstruction?

The article, titled "Tracheobronchial resection and reconstruction: to wrap or not to wrap the anastomosis?",presents a single-center experience to explore the relationship between wrapping the anastomosis after airway reconstruction and short-term surgical outcomes, and to investigate whether wrapping the anastomosis can reduce the incidence of postoperative adverse events.

【Backgrounds】

Tracheobronchial resection and reconstruction surgery still technically demanding procedure with high risks of morbidity and mortality. According to experience of MGH, neoadjuvant treatment and tracheal resection>4 cm may associated with increased anastomotic complication rate. Accurate preoperative planning of airway reconstruction strategies and ensuring proper tension and good healing of the anastomotic site are crucial for the prognosis of surgical patients.

The wrapping of autologous tissue materials around the anastomosis is considered a potential method to prevent complications at the anastomotic site. Various autologous tissues, including pedicled muscle flaps, pleura, glands, and omentum, have also been reported for use in wrapping the anastomosis after airway reconstruction. However, previous studies hold the view that accurate suturing techniques and protecting surrounding airway structures (such as blood vessels and lymph nodes) are key to preventing anastomotic complications during the procedure, making additional wrapping unnecessary. Whether to wrap the anastomosis with surrounding tissue remains controversial.

【Main findings】

Overall, 95 patients (31.6% female) were included in the study, including 42 patients underwent complex surgery (wrapped subgroup: 32, non-wrapped subgroup: 10), and 53 patients received standard surgery (wrapped subgroup: 32, non-wrapped subgroup: 21). In the complex surgery group, the wrapped subgroup exhibited a significantly lower short-term postoperative anastomotic complication rate compared to the non-wrapped subgroup (P=0.004). Long-term anastomotic complication rate was comparable between 2 groups. No statistically significant differences were observed in the standard surgery group.

【Clinical significance】

The wrapping procedure has a relatively positive effect on the short-term prognosis of patients undergoing complex tracheobronchial resection and reconstruction, particularly in minimizing the risk of anastomotic complications to a certain extent. As airway resections and reconstruction become more common, revisiting and refining peri-anastomotic strategies is critical for optimizing outcomes.

END



ELSE PRESS RELEASES FROM THIS DATE:

Understanding how a key protein helps aggressive blood cancer grow, paving the way for targeted therapies

2025-06-25
Acute myeloid leukemia (AML) is an aggressive cancer affecting the blood and bone marrow that progresses rapidly, making immediate treatment essential. While chemotherapy and targeted drugs have improved outcomes for some patients, many forms of AML remain resistant to treatment, and relapses are common.   A new study sheds light on why certain types of AML are so challenging to treat and how outcomes for patients might be improved. Researchers from Japan, including scientists from Chiba University, have discovered ...

Uncovering the role of vitamin C in skin regeneration

2025-06-25
The skin acts as the body’s first line of defense against external threats. However, as we age, the epidermis—the outermost layer of skin—gradually becomes thinner and loses its protective strength. About 90% of the cells in this layer are keratinocytes, which originate from deeper layers of the epidermis and migrate upward, ultimately forming the skin’s protective barrier. To combat aging’s impact on skin, numerous studies have emphasized the benefits of vitamin C (VC), a vitamin well known for its role in skin health and antioxidant ...

Advancing regenerative agriculture: TUdi unveils new digital tools for soil health monitoring

2025-06-25
Technology plays a pivotal role across industries today, and agriculture is no exception. In the realm of regenerative agriculture - an approach focused on conserving and restoring soil health and biodiversity - technology is key in enhancing data collection, monitoring, and supporting informed decision-making.  TUdi is a collaborative project between the European Union and China funded by the European Commission and the Chinese Ministry of Science and Technology, within the Horizon 2020 programme. The project's goal is to develop and promote soil-restoration strategies ...

More staff addressing mental health in schools buffers toll of growing up in disadvantaged communities

2025-06-25
Children growing up in disadvantaged neighborhoods—communities with low rates of high school graduation and employment, low family income, and other measures of adversity—are at heightened risk of experiencing mental health conditions. But a new study from Mass General Brigham suggests that, while neighborhood environment plays a key role in mental health, having greater access to mental health staff in schools could help lower risk.   In a study of 30,000 high school and middle school students at 62 schools ...

Still top cause of death, the types of heart disease people are dying from is changing

2025-06-25
Research Highlights: Over the past 50 years, overall heart disease death rates have dropped by 66% and deaths from heart attacks have declined by nearly 90%. The types of heart disease people are dying from most often have shifted from heart attacks to an increase in deaths from heart failure, arrhythmias and hypertensive heart disease. Researchers say this shift, in part, is the result of advances in public health measures focused on prevention and life-saving interventions to improve early diagnosis and treatment, allowing people to live longer while managing chronic heart conditions   DALLAS, June 25, 2025 — While heart disease has been the leading ...

Scientists detect deep Earth pulses beneath Africa

2025-06-25
Research led by Earth scientists at the University of Southampton has uncovered evidence of rhythmic surges of molten mantle rock rising from deep within the Earth beneath Africa. These pulses are gradually tearing the continent apart and forming a new ocean. The findings, published in Nature Geoscience, reveal that the Afar region in Ethiopia is underlain by a plume of hot mantle that pulses upward like a beating heart. The team’s discovery reveals how the upward flow of hot material from the deep mantle is strongly influenced by the tectonic plates – the massive solid slabs ...

As fewer Americans die from heart attacks, more succumb to chronic heart disease

2025-06-25
In 1970, someone over the age of 65 hospitalized for a heart attack in the United States had about a 60% chance of leaving the hospital alive. Today, the survival rate is over 90%, with even better outcomes for younger patients. Those numbers have contributed to a remarkable decrease in the likelihood of dying from any type of heart disease over the last 50 years, according to a new study of heart disease mortality led by Stanford Medicine researchers. In 1970, 41% of all deaths were attributed to ailments of the heart; in 2022, that statistic had dropped to 24% of all deaths.  Most strikingly, the proportion ...

Guidance issued for GPs managing weight-loss injection patients

2025-06-25
Academics at King’s College London and the University of East Anglia have released guidance for GPs on how to manage patients who may be privately accessing weight loss drugs. The medications are not routinely prescribed for obesity management in primary care. But it is estimated 1.5million people used weight-loss jabs in March 2025 with 80% of purchases through online retailers. As these users are privately accessing the medication, providers do not always provide wrap-around care such as dietary advice or psychological support. The authors of the guidance, published today in Obesity Facts, say the ten evidence-based tips aim to help GPs who see patients using ...

Low-cost carbon capture? Bury wood debris in managed forests

2025-06-25
CORNELL UNIVERSITY MEDIA RELATIONS OFFICE FOR RELEASE: June 25, 2025   Kaitlyn Serrao 607-882-1140 kms465@cornell.edu Low-cost carbon capture? Bury wood debris in managed forests ITHACA, N.Y. – Taking carbon out of the atmosphere is essential for slowing global warming – and a team of Cornell University researchers has estimated “huge” potential for carbon capture using a method that is low-tech, sustainable and relatively simple: burying wood, especially the debris from managed ...

Scientists unravel mystery of Mycetoma grain formation

2025-06-25
Osaka, Japan – A groundbreaking study led by a global research consortium offers new hope for patients with mycetoma, a neglected tropical disease. Researchers using an insect model and transcriptome analysis have unravelled the mechanism of iron regulation between host tissue and the mycetoma grain, a fungal mass characteristic of the disease. This discovery illuminates how the causative fungus invades and develops these protective grains within subcutaneous tissue, paving the way for new drug development and less invasive treatment strategies beyond surgical removal, potentially reducing the burden on patients significantly. Mycetoma, a chronic infectious ...

LAST 30 PRESS RELEASES:

Mayo Clinic researchers use AI to predict patient falls based on core density in middle age

Moffitt study develops new tool to predict how cancer evolves

National Multiple Sclerosis Society awards Dr. Manuel A. Friese the 2025 Barancik Prize for Innovation in MS Research

PBM profits obscured by mergers and accounting practices, USC Schaeffer white paper shows

Breath carries clues to gut microbiome health

New study links altered cellular states to brain structure

Palaeontology: Ancient giant kangaroos could hop to it when they needed to

Decoded: How cancer cells protect themselves from the immune system

ISSCR develops roadmap to accelerate pluripotent stem cell-derived therapies to patients

New study shows gut microbiota directly regulates intestinal stem cell aging

Leading cancer deaths in people younger than 50 years

Rural hospital bypass by patients with commercial health insurance

Jumping giants: Fossils show giant prehistoric kangaroos could still hop

Missing Medicare data alters hospital penalties, study finds

Experimental therapy targets cancer’s bodyguards, turning foe to friend to eliminate tumors

Discovery illuminates how inflammatory bowel disease promotes colorectal cancer

Quality and quantity? The clinical significance of myosteatosis in various liver diseases

Expert consensus on clinical applications of fecal microbiota transplantation for chronic liver disease (2025 edition)

Insilico Medicine to present three abstracts at the 2026 Crohn’s & Colitis Congress highlighting clinical, preclinical safety, and efficacy data for ISM5411, a novel gut-restricted PHD1/2 inhibitor fo

New imaging technology detects early signs of heart disease through the skin

Resurrected ancient enzyme offers new window into early Earth and the search for life beyond it

People with obesity may have a higher risk of dementia

Insilico Medicine launches science MMAI gym to train frontier LLMs into pharmaceutical-grade scientific engines

5 pre-conference symposia scheduled ahead of International Stroke Conference 2026

To explain or not? Need for AI transparency depends on user expectation

Global prevalence, temporal trends, and associated mortality of bacterial infections in patients with liver cirrhosis

Scientists discover why some Central Pacific El Niños die quickly while others linger for years

CNU research explains how boosting consumer trust unlocks the $4 billion market for retired EV batteries

Reimagining proprioception: when biology meets technology

Chungnam National University study finds climate adaptation can ease migration pressures in Africa

[Press-News.org] Technical refinement in airway surgery: Wrapping tracheobronchial anastomoses