(Press-News.org) CLEVELAND—Epilepsy is among the most common neurological conditions, marked by unpredictable seizures, accidents and injuries, reduced quality of life, stigma and—in the worst case—premature death.
But a program—developed over several years by a Case Western Reserve University-led research team—that teaches people with epilepsy how to “self-manage” their disorder is showing positive results.
The program has been found to help people with epilepsy reduce related health complications and improve their mood and quality of life, according to a new study recently published in the peer-reviewed journal, Epilepsy & Behavior.
“Results of this study provide a model for broad and practical expansion of the program to people with epilepsy,” said Martha Sajatovic, the L. Douglas Lenkoski MD Professor in Psychiatry at the Case Western Reserve University School of Medicine.
Sajatovic, who co-led the study funded by the U.S. Centers for Disease Control and Prevention (CDC), is also the Willard Brown Chair in Neurological Outcomes Research and director of the Neurological and Behavioral Outcomes Center at University Hospitals Cleveland Medical Center. The study was also co-led by Gena Ghearing, formerly at the University of Iowa and now a professor of neurology at the Icahn School of Medicine at Mount Sinai in New York. Collaborators also included researchers at the University of Cincinnati.
Self-managing the disorder
Epilepsy is a chronic health condition triggered by abnormal electrical activity in the brain
in which individuals experience recurrent—and usually unpredictable—seizures. According to the CDC:
1.2% of the United States population has active epilepsy. That’s about 3 million adults and 470,000 children nationally.
Epilepsy can last a lifetime and may be triggered by events like stroke and traumatic brain injury.
Given that people with chronic health conditions often have limited contact with their healthcare providers, self-management interventions have gained increasing attention for their potential benefit.
In particular, how well epilepsy patients manage the condition depends on their daily behavior, such as consistently taking medication, proper nutrition, exercise, stress management and avoiding activities or triggers that can make it more likely for seizures to occur, such as being sleep-deprived.
With that in mind, the CDC’s Managing Epilepsy Well (MEW) network has led the development, testing and growth of various successful epilepsy self-management approaches over the last dozen years.
Among them is a program Sajatovic and the Case Western Reserve team developed, called SMART, to support people with epilepsy who have experienced health complications, including poorly controlled seizures.
How it works
SMART features remote self-management training sessions for groups of six to 10 people with epilepsy. They meet by video conferencing for about an hour weekly for eight to 10 weeks.
The sessions are led by a nurse and “peer educator”—a person with epilepsy trained to deliver the detailed curriculum designed to help people learn to better manage and cope with their epilepsy and improve their overall well-being. Participants also get written resource materials to help them continue to practice refining their epilepsy self-management skills.
“Many people who participate in our SMART program have never been in a group with other people with epilepsy and find this a particularly valuable and rewarding part of the program,” Sajatovic said.
The study
SMART’s effectiveness was measured in two independent research studies. The published report summarizes the results of a clinical research study of 160 people with epilepsy. Half used the SMART program; half did not.
Compared to the control group, people with epilepsy who participated in the SMART program demonstrated reduced complications of the condition as well as improved mood and quality of life and an increase in the ability to manage their epilepsy.
“This new clinical trial confirms the positive effects of SMART and also demonstrates how effective a simple and relatively inexpensive telehealth delivery can be,” Sajatovic said.
What’s ahead
The study team at Case Western Reserve has made substantial progress to refine, implement and expand the SMART program in community settings by collaborating with the Epilepsy Association in Cleveland, the Epilepsy Alliance of Ohio and the Epilepsy Association of Western and Central Pennsylvania, as well as with epilepsy treatment centers in Ohio and in Iowa.
“I am most excited about the possibility of establishing successful models of delivering SMART that can be used by clinical-care teams and by epilepsy-focused social services agencies,” Sajatovic said. “I am hopeful that we can make the SMART program available to as many people with epilepsy as possible.”
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At Case Western Reserve, one of the nation's leading research universities, we're driven to seek knowledge and find solutions to some of the world's most pressing problems. Nearly 6,200 undergraduate and 6,100 graduate students from across 96 countries study in our more than 250 degree programs across arts, dental medicine, engineering, law, management, medicine, nursing, science and social work. Our location in Cleveland, Ohio—a hub of cultural, business and healthcare activity—gives students unparalleled access to engaging academic, research, clinical, entrepreneurial and volunteer opportunities and prepares them to join our network of 125,000+ alumni making an impact worldwide. Visit case.edu to learn more.
About University Hospitals / Cleveland, Ohio
Founded in 1866, University Hospitals serves the needs of patients through an integrated network of more than 20 hospitals (including five joint ventures), more than 50 health centers and outpatient facilities, and over 200 physician offices in 16 counties throughout northern Ohio. The system’s flagship quaternary care, academic medical center, University Hospitals Cleveland Medical Center, is affiliated with Case Western Reserve University School of Medicine, Northeast Ohio Medical University, Oxford University, Taiwan National University College of Medicine and the Technion Israel Institute of Technology. The main campus also includes the UH Rainbow Babies & Children's Hospital, ranked among the top children’s hospitals in the nation; UH MacDonald Women's Hospital, Ohio's only hospital for women; and UH Seidman Cancer Center, part of the NCI-designated Case Comprehensive Cancer Center. UH is home to some of the most prestigious clinical and research programs in the nation, with more than 3,000 active clinical trials and research studies underway. UH Cleveland Medical Center is perennially among the highest performers in national ranking surveys, including “America’s Best Hospitals” from U.S. News & World Report. UH is also home to 19 Clinical Care Delivery and Research Institutes. UH is one of the largest employers in Northeast Ohio with more than 30,000 employees. Follow UH on LinkedIn, Facebook and Twitter. For more information, visit UHhospitals.org.
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Epilepsy self-management program shows promise to control seizures, improve mood and quality of life
2025-07-01
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