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New tech speeds up AI training for drug discovery/disease research

2025-08-14
(Press-News.org) University of Oregon bioengineer Calin Plesa has developed technology that creates massive, high-quality biological datasets at unprecedented speed and scale, solving a critical bottleneck that has prevented AI from tackling biology's biggest challenges—from studying cancer-associated genes to designing new proteins to accelerating drug development. In research detailed in the latest edition of Science Advances, Plesa used this technology to uncover genetic factors behind antimicrobial resistance, demonstrating how to generate the vast datasets needed to train powerful machine learning systems faster and cheaper than ever before.  

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ELSE PRESS RELEASES FROM THIS DATE:

Researchers synthesize a new allotrope of carbon

2025-08-14
Images available via the multimedia section. Chemists have demonstrated the synthesis of a new molecular form of carbon. The new molecule – cyclo[48]carbon, made up of 48 carbon atoms in an alternating single/triple bond pattern – is stable enough to be studied in liquid solution form at room temperature. The study – only the second example of a new type of molecular carbon allotrope that can be studied under normal laboratory conditions – has been published today (14 August) in Science. In a new study led by Oxford University’s Department of Chemistry, chemists have demonstrated the synthesis ...

Scientists hack microbes to identify environmental sources of methane

2025-08-14
Roughly two-thirds of all emissions of atmospheric methane — a highly potent greenhouse gas that is warming planet Earth — come from microbes that live in oxygen-free environments like wetlands, rice fields, landfills and the guts of cows. Tracking atmospheric methane to its specific sources and quantifying their importance remains a challenge, however. Scientists are pretty good at tracing the sources of the main greenhouse gas, carbon dioxide, to focus on mitigating these emissions. But to trace methane’s origins, scientists often have to measure the isotopic composition of methane's component atoms, carbon and hydrogen, to ...

New high blood pressure guideline emphasizes prevention, early treatment to reduce CVD risk

2025-08-14
Guideline Highlights: Nearly half of all adults in the U.S. have high blood pressure (≥130/80 mm Hg), which is the #1 preventable risk factor for cardiovascular disease, including heart attack, stroke and heart failure, as well as kidney disease, cognitive decline and dementia. A new joint guideline from the American Heart Association and the American College of Cardiology advises earlier treatment that includes lifestyle modification and medications as appropriate, recommends close blood pressure ...

"Every Brilliant Thing”, the interactive one-person play with a suicidality theme now making its West End debut, reduced suicide-associated stigma among university students who attended, even up to 30

2025-08-14
"Every Brilliant Thing”, the interactive one-person play with a suicidality theme now making its West End debut, reduced suicide-associated stigma among university students who attended, even up to 30 days later. +++ Article URL: https://plos.io/411ECQu Article Title: A performing arts intervention to decrease suicide stigma on campus: A three time point assessment of “Every Brilliant Thing” Author Countries: United States Funding: The authors received no specific funding for this ...

Climate models reveal human influence behind stalled pacific cycle

2025-08-14
A new CU Boulder-led study has revealed that recent changes in North Pacific Ocean temperatures—long believed to be the result of natural variability—are in fact being driven by human-generated greenhouse gas and industrial aerosol emissions. These oceanic shifts are directly linked to the prolonged megadrought gripping the American Southwest, and this research published August 13th in Nature suggests it may not ease for another 30 years. “Our results show that the drought and ocean patterns we’re seeing today are not just natural fluctuations—they’re largely driven by human activity,” ...

Laying the foundation for gene editing for inherited progressive deafness in adults, DFNA41

2025-08-14
Zheng-Yi Chen, DPhil, associate scientist at the Eaton-Peabody Laboratories, and Ines and Fredrick Yeatts Chair in Otolaryngology, at Mass Eye and Ear, is the senior and co-corresponding author of a paper published in the Journal of Clinical Investigation, “Single Dose Genome Editing Therapy Rescues Auditory and Vestibular Functions in Adult Mice with DFNA41 Deafness.” Q: How would you summarize your study for a lay audience? This study provides an example of a successful use of gene editing technology to treat a mouse model of human genetic hearing loss. We developed a one-time, gene editing ...

Monell Center researchers present latest findings at International Meeting on Consumer Sensory Science

2025-08-14
Monell Center Researchers Present Latest Findings at International Meeting On Consumer Sensory Science Coinciding with the 2025 Philadelphia-based conference, Monell - the first independent nonprofit dedicated to smell and taste research - hosts academic, industry partners for visits, collaborations  PHILADELPHIA (Aug 14, 2025) – Scientists from the Monell Chemical Senses Center will present their research at the 16th Pangborn Sensory Science Symposium, “Connecting Senses and Minds,” August 17-21, 2025 ...

AFAR receives NIH award renewal totaling more than $5.7 million for the Nathan Shock Centers Coordinating Center

2025-08-14
NEW YORK — The American Federation for Aging Research (AFAR) has received a five-year renewal award totaling $5,722,435 from the National Institute on Aging (NIA), part of the National Institutes of Health (NIH), to continue and expand the Nathan Shock Centers Coordinating Center (NSC3). The NSC3 coordinates the activities of the 8 Nathan Shock Centers (NSC) of Excellence in the Basic Biology of Aging, which provide expert resources to expand basic research into the biology of aging. The NSCs began in 1995 in honor of ...

Brain-computer interface could decode inner speech in real time

2025-08-14
Scientists have pinpointed brain activity related to inner speech—the silent monologue in people’s heads—and successfully decoded it on command with up to 74% accuracy. Publishing August 14 in the Cell Press journal Cell, their findings could help people who are unable to audibly speak communicate more easily using brain-computer interface (BCI) technologies that begin translating inner thoughts when a participant says a password inside their head.  “This is the first time ...

Cancer drug eliminates aggressive cancers in clinical trial

2025-08-14
Over the past 20 years, a class of cancer drugs called CD40 agonist antibodies have shown great promise—and induced great disappointment. While effective at activating the immune system to kill cancer cells in animal models, the drugs had limited impact on patients in clinical trials and caused dangerously systemic inflammatory responses, low platelet counts, and liver toxicity, among other adverse reactions—even at a low dose. But in 2018, the lab of Rockefeller University’s Jeffrey V. Ravetch demonstrated it could engineer an enhanced CD40 ...

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[Press-News.org] New tech speeds up AI training for drug discovery/disease research