PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Deprivation and transport density linked to increased suicide risk in England

2025-08-14
(Press-News.org) *Embargoed links to the paper, regional data, and additional quotes are available at the end of this press release* 

IMPERIAL COLLEGE LONDON PRESS RELEASE
Peer Reviewed / Observational study / People                       

An analysis of suicide rates in England has shown how factors like deprivation and transport density are linked to regional increases in suicide risk.

The first of its kind study, led by researchers at Imperial College London, UCL and the London School of Economics and Political Science (LSE), looked at suicide trends in England from 2002 to 2022 combined with the influence of local socio-environmental factors on risk.

In an analysis of national mortality data over the 20-year period, they found that local areas with higher levels of social deprivation, as well as increased rail and road network density, were linked with an increased suicide risk. Higher levels of ethnic diversity, population density, light pollution and green space, were linked with a lower risk. However, the study did not consider method of suicide.

While there was no significant change in the overall suicide rate in England from 2002-2022 (which remained around 11 suicide deaths per 100,000 people), the study found significant variations in regional suicide risks – with the highest relative risk values in the North-East of England (14.48% above national average), and the lowest risk in London (17.74% below national average) – with a difference of 39.2% between the highest and lowest risk regions (using an average of year on year comparisons[1]).

According to the researchers, the work helps to highlight the role of local social and environmental factors on suicide risk. They explain that their model could be used to bring new insights into local risk factors for suicide and identify higher risk areas which could ultimately help to improve and target national and regional prevention strategies.

They add that the work aligns with the goals of the recently published NHS 10-Year Health Plan, promoting prevention and early intervention and a commitment to reducing the number of lives lost to the biggest killers, including suicide.[2] 

The study, published today in the journal The Lancet Regional Health - Europe, was supported by funding from Wellcome Trust, UK Health Security Agency, UKRI Medical Research Council (MRC) and the National Institute for Health and Care Research (NIHR).

Dr Connor Gascoigne, from Imperial’s School of Public Health and first author of the study, said: “Our analysis suggests that people living in deprived and isolated areas may have increased risk of dying from suicide – while some social factors have a seemingly protective effect. While many of these risk factors are well established, our methods could be used as a tool to track how these factors change over time and their impact on suicide risk and inform policy.

“We know inequalities can have huge and lasting impacts on people’s health, but also on suicide risk. This work highlights not only the need for improved regional services focused on prevention, but also that national policies are urgently needed to reduce regional inequalities across the UK.”

NATIONAL SUICIDE TRENDS
Each year in the UK there are an average of 6,300 suicide deaths, equivalent to 11 per 100,000 people.[3] While individual risk factors for suicide are complex and variable, such as mental illness, substance use or chronic pain, they are well-recognised. But much less is known about local level risk factors for suicide and how they change over time.

In the latest study, researchers analysed data from the Office for National Statistics (ONS) on suicide deaths in England from 2002-2022. These data covered 6,791 administrative areas in England, each containing up to 15,000 people. The team used date of death, rather than the date the cause of death was registered as suicide – the latter often delayed due to coroners’ investigations and reports. Details of suicide method were not captured in the model.

The team combined these data with information on socio-environmental factors they predicted might be associated with suicide risk at the local level. These included measures of deprivation, ethnic density, population density, light pollution, railway network density, road network density, and green space.

Analysis of the national trend over time found that there was no significant change from 2002-2022 (with variations around an average of 11 suicide deaths per 100,000 people over the period), but there were year on year fluctuations in relative risks for England – with a low point in 2007 and a peak in 2019 (with Relative Risks of 0.92 and 1.09, respectively). Similar results have been reported where England and Wales have seen a consistent 11.0 suicides per 100,000 with a change from 9.0 to 10.9 per 100,000 from 2002 to 2022.[4]

 

                 

Relative Risk over the 2002-2022 period in England (left) and regionally (right)

Dr Gascoigne, who carried out the analyses at Imperial’s MRC Centre for Environment and Health, added: “It’s important to stress that while our study found no significant change in the national suicide rate between 2002-2022, this by no means negates the existing services in place and the efforts of those working to help people at risk and to reduce deaths from suicide. Indeed, it may show that such policies have helped to buffer the impacts of significant national and global events, such as the COVID-19 pandemic.

“We do hope that our approach could provide crucial evidence-informed approach to monitoring the impact of such environmental factors over time, to better protect vulnerable individuals and reduce suicide risk in England.”

REGIONAL SUICIDE TRENDS
Regionally, the North East and North West of England had higher suicide rates than the national average across the 20-year period (an average of 14.48% and 11.42%, respectively). The South West also had a consistently higher than average suicide rate across most years (9.76%). London was the only region where the rate was below the national average for all years (-17.74%), with suicide risk in London 39.2%[1] lower than in the North East of England overall. [See the Table in notes to editors for regional figures].

When modelling the impact of environmental factors on suicide risk, the researchers found that for each standard deviation increment in the predictor investigated, suicide risk increased with deprivation (20.06%), road network density (5.16%) and railway network density (1.37%). But suicide risk decreased with ethnic density (-7.47%), population density (-5.42%), light pollution (-4.20%), and greenspace composition (-6.43%).

The researchers highlight several limitations to the study, including that the data only cover England, as well as the limited detailed information available on the deceased individuals – while data on age and sex were available, they were unable to identify ethnicity, or information on other factors such as family structure, employment or socioeconomic status.

Professor Marta Blangiardo, from Imperial’s School of Public Health and senior author of the study, said: “The health and social impacts of social deprivation on communities in the UK are well established. We know that people in poorer regions of the country, with fewer job opportunities and fewer public services, have stark differences in life expectancy and health compared to those living in the least deprived areas of the country. This rings true in our analysis.

“While any number of complex individual factors can increase a person’s risk of death by suicide, we find that local factors – such as living in an isolated area or a heavily industrialised area with greater deprivation – may have a significant impact on an individual’s suicide risk. These findings should help to inform and drive policy changes to further reduce suicide rates in England, in line with the goals of the NHS Long Term Plan.”

Professor Alexandra Pitman, Professor of Psychiatry at University College London, and study co-author, said: “There is a lot of policy interest in understanding spatial influences on suicide risk because of the potential for local authorities to address these factors at the area level and reduce suicide risk for a large number of people in their populations. We know there is a well-established association between social deprivation and suicide risk, and we can understand why, so our finding that area-level deprivation was associated with suicide may not be that surprising. However, our finding that factors such as greater road network density and railway network density were associated with higher suicide risk, and that greater light pollution are associated with higher suicide risk are striking. We need to understand how these pathways operate in order to work out how to intervene to reduce risk.

“To take the example of transport network density, it is possible that roads and railway lines create noise or air pollution, which was why we were keen to investigate this as a potential influence on suicide risk. However, transport lines can also carve physical barriers through communities or provide access to the means of suicide, and these might explain the increased risk instead. We should also take into account that having better transport connectivity to others might improve mental health and reduce suicide risk. This example shows that a study of this kind is valuable in identifying important macro-level patterns, directing our focus on understanding how preventive efforts might operate and how they might best be delivered.”

Niall Boyce, Head of Knowledge and Measurement in Mental Health at Wellcome said: “These findings illustrate how scientific research can help us to untangle some of the complex associations between environment and poor mental health. Ultimately, better understanding of these factors will help us to design and deliver interventions to those who need them, at the earliest possible stage.”

The work was supported by the NIHR through its Health Protection Research Units (HPRUs) at Imperial College London in Environmental Exposures and Health and in Chemical and Radiation Threats and Hazards, and through Health Data Research UK (HDR UK) in the Social and Environmental Determinants of Health Driver Programme.

The work at Imperial was also underpinned by infrastructure support from the NIHR Imperial Biomedical Research Centre, a translational research partnership between Imperial College Healthcare NHS Trust and Imperial College London.

-

‘Spatio-temporal trends and socio-environmental determinants of suicides in England (2002 – 2022): an ecological population-based study’ by Gascoigne, C., Jeffery, A., Rotous, I., et al. is published in The Lancet Regional Health - Europe. DOI: 10.1016/j.lanepe.2025.101386

 

Please refer to the Samaritans Media Guidelines for reporting suicide: https://www.samaritans.org/about-samaritans/media-guidelines/  

As per the recommendations in the Samaritans Media Guidelines, when producing content on the topic of suicide, please signpost to sources of support in your reporting of this story. 

·        In the UK, you can contact Samaritans for free on 116 123, email them at jo@samaritans.org, or visit www.samaritans.org to find your nearest branch. 

·        Outside of the UK, the Befrienders Worldwide website has a tool to search by country for helplines around the world, visit https://befrienders.org


 

This press release uses a labelling system developed by the Academy of Medical Sciences to improve the communication of evidence. For more information, please see: http://www.sciencemediacentre.org/wp-content/uploads/2018/01/AMS-press-release-labelling-system-GUIDANCE.pdf

 

NOTES TO EDITORS:
Differences in regional suicide risk in England compared to the national average.

Region

2002
(% difference from national average)

2022
(% difference from national average)

Average 2002-2022

(% difference from national average)

North East

10.03%

23.16%

14.48%

North West

8.81%

12.93%

11.42%

South West

13.58%

9.87%

9.76%

Yorkshire and The Humber

12.46%

9.82%

4.00%

West Midlands

8.48%

-5.25%

-1.61%

East Midlands

4.27%

-4.97%

-1.79%

South East

-0.98%

0.13%

-2.45%

East of England

1.85%

-1.27%

-4.89%

London

-8.28%

-23.19%

-17.74%


[1] The calculation for London vs North East (39.2%) uses a direct year-on-year comparison to generate an average (comparing London vs North East for each year, and then taking the mean of these results).

By comparison, the difference between the figures for London and the North East in the Table (32.22%) is generated from summaries over the 20-year period (i.e. the difference between the two averages for London and North East across 20 years).

 

[2] ‘Fit for the Future: 10 Year Health Plan for England’, NHS England, 2025.
https://assets.publishing.service.gov.uk/media/68760ad755c4bd0544dcae33/fit-for-the-future-10-year-health-plan-for-england.pdf

(Pg. 86) ‘As well as preventing the worst cases of neglect, our focus on quality will drive up standards for everyone. For example, it will be through our quality agenda that we achieve our Plan for Change commitment to reduce the number of lives lost to the biggest killers, including cancer, cardiovascular disease (CVD), and suicide.’

(Pg. 112) ‘New digital tools, digitised therapies and real-time suicide surveillance will improve mental health and reduce suicide rates.’

 

[3] ‘The National Confidential Inquiry into Suicide and Safety in Mental Health. Annual Report: UK patient and general population data 2011-2021’, University of Manchester, 2024. (pg. 10)
Available from: https://documents.manchester.ac.uk/display.aspx?DocID=71818

 

[4] ‘Suicide statistics’, Commons Library Research Briefing, 8 January 2025., by Esme Kirk-Wade.
https://researchbriefings.files.parliament.uk/documents/CBP-7749/CBP-7749.pdf

 

ADDITIONAL QUOTES:

Professor Sir Louis Appleby, from the University of Manchester and Chair of the National Suicide Prevention Strategy Advisory Group, who was not involved in the research, said: “A lot has happened to suicide rates in England & Wales in the last 20 years. A long-term fall culminated in 2007 in the lowest rate on record. The 2008 global recession put rates up, the global pandemic did not. After 2008 the pattern of suicide changed – middle aged men were now the group at highest risk and a gap opened up between London and other regions, especially the North-East. Rates in young people rose steadily, though have now levelled off.

“In 2018 a new standard of proof led to a jump in suicide conclusions at inquest – with national data, definition is everything and figures pre- and post-2018, as in this study, may not be strictly comparable. These new findings too remind us that suicide rates are complex, reflecting how and where we live, frequently changing. They show the breadth of measures that any national prevention policy should embrace, and the need for constant vigilance.”

James Fildes, Founder & Managing Director of Space North East and Chair of Washington Mind, who was not involved in the research, said: “It’s of little surprise to us the lack of substantial improvement in suicide rates across the nation, and more specifically with regard to any improvement in the North East. The data presented in this study strengthens long-held, but typically anecdotal, beliefs around geographical and societal patterns of suicidality. For example there is significant data indicating that the North East of England typically experiences the highest rates of suicide nationally, however the further extrapolation of that inquiry to include area-level risk factors is a welcome piece to an increasingly complex puzzle.

“Growing up in the North East, in the once impressive, now de-industrialised city of Sunderland, it was clear to see the impact of that de-industrialisation since the closure of the mines and shipyards, with the final nail in the coffin coming in 1988. The closure of such pivotal industries was damaging enough, but the lack of support, infrastructure and importantly resource that followed, or rather didn’t follow, left in its wake a population of skilled, hard-working men & women that struggled for work and struggled for opportunity. We see this in our service on a daily basis, a lack of purpose, opportunity and support across generations has left people feeling apathetic, hopeless and tied to an almost mythologised “good old days”, which, will of course, never return.

“This study has done its job in empirically highlighting what was abundantly clear from a community-led, once again anecdotal perspective, and for that we absolutely support the fantastic efforts of the collaborative team involved. However, I would be remiss if I did not highlight the obvious, that there needs to be more channelling of resources and focus paid to those organisations and communities that are furthest from Westminster, such as the North East, the North West and South West as highlighted in this study.

“We look forward to seeing the further outputs of this study and are willing to participate in any capacity, to highlight the significant issues that are faced in the aforementioned regions of our country. It’s important to highlight that the uplifting of such regions, is a win for all and requires more of this research and subsequent resource to be channelled into areas most greatly impacted by suicide. There are so many green shoots of progress made by community organisations across the UK and existing research from prominent academics such as the acknowledged and estimable Professor Louis Appleby, whose involvement in this area has already done so much. Finally, we look forward to the follow up of this study and encourage all who have participated in this or parallel studies, to ask themselves “so what?”. How do we follow up this research with tangible, evidence-based, accessible and practical solutions so these findings can become a foundation we’ve built success from, not a stick we beat ourselves with for generations to come.”

 

ABOUT IMPERIAL COLLEGE LONDON

We are Imperial – a world-leading university for science, technology, engineering, medicine and business (STEMB), where scientific imagination leads to world-changing impact.   

As a global top ten university in London, we use science to try to understand more of the universe and improve the lives of more people in it. Across our nine campuses and throughout our Imperial Global network, our 22,000 students, 8,000 staff, and partners work together on scientific discovery, innovation and entrepreneurship. Their work navigates some of the world’s toughest challenges in global health, climate change, AI, business leadership and more.  

Founded in 1907, Imperial’s future builds on a distinguished past, having pioneered penicillin, holography and fibre optics. Today, Imperial combines exceptional teaching, world-class facilities and a habit of interdisciplinary practice to unlock scientific imagination.  

https://www.imperial.ac.uk/

 

ABOUT NIHR

The mission of the National Institute for Health and Care Research (NIHR) is to improve the health and wealth of the nation through research. 

We do this by:

funding high quality, timely research that benefits the NHS, public health and social care investing in world-class expertise, facilities and a skilled delivery workforce to translate discoveries into improved treatments and services partnering with patients, service users, carers and communities, improving the relevance, quality and impact of our research attracting, training and supporting the best researchers to tackle complex health and social care challenges collaborating with other public funders, charities and industry to help shape a cohesive and globally competitive research system funding applied global health research and training to meet the needs of the poorest people in low and middle income countries NIHR is funded by the Department of Health and Social Care. 

Our work in low and middle income countries is principally funded through UK international development funding from the UK government.

END



ELSE PRESS RELEASES FROM THIS DATE:

Flatworms can replace rats for breakthrough brain studies

2025-08-14
Tiny pond worms could help find new ways to treat schizophrenia, develop understanding around drug addiction and test new medicines for mental illnesses – all while reducing the number of mice and rats used in early medical research.  Scientists from the University of Reading say that planaria - harmless flatworms found in ponds and rivers - react to brain medicines in ways similar to rodents. When given haloperidol, a drug used to treat mental health conditions, the worms became much less active, ...

Plastic from plants: FAMU-FSU College of Engineering professor uses material in plant cell walls to make versatile polymer

2025-08-14
In Ho Yong Chung’s laboratory, magic is at work — plants turn into plastics. In new research, Chung, an associate professor in the FAMU-FSU College of Engineering, showed for the first time the possibility of using lignin, a material found in plant cell walls, and carbon dioxide to create a new kind of polyurethane, a polymer used in various applications for its ability to regulate heat, flexibility during processing and strength as a finished product. The work was published in ACS Sustainable Chemistry & Engineering. “We’ve ...

Leaders at Huntsman Cancer Institute drive theranostics expansion to transform cancer care

2025-08-14
Huntsman Cancer Institute at the University of Utah (the U) announces leadership team appointments overseeing clinical and research efforts in theranostics, an innovative approach to radiation treatment for cancer that combines diagnostics and therapeutics.  Heloisa Soares, MD, PhD, Huntsman Cancer Institute medical oncologist and associate professor of internal medicine at the U, will serve as medical director of the theranostics program.  Theranostics is a powerful new way to both find and treat cancer. It uses radioactive drugs—called radiopharmaceuticals—that ...

Thin films, big science: FSU chemists expand imaging possibilities with new X-ray material

2025-08-14
Most people picture a doctor checking for a broken bone when they think of an X-ray. But the technology is just as important in places like airport security, manufacturing, quality control and scientific research, each with its own criteria for size and shape.  A team led by Florida State University Professor of Chemistry and Biochemistry Biwu Ma has developed a new form for X-ray materials that can meet the needs of large-area applications, changing out complex crystal structures for an adaptable and scalable thin-film detector. The work was published in Angewandte Chemie.  “We took a material we developed and made it better,” Ma said. “This ...

66th Supplement to the Check-list of North American Birds publishes today in Ornithology

2025-08-14
CHICAGO — August 14, 2025  — The 66th Supplement to the American Ornithological Society’s (AOS’s) Check-list of North American Birds, published today in Ornithology, includes several significant updates to the classification of bird species found in North America, Central America, and the Caribbean. A few highlights from the supplement, detailed below, include species splits for Myiarchus nuttingi, Vireo gilvus, and Larus argentatus; the addition of subfamilies in the Laridae for white-terns and noddies; and a merging of three families ...

Canadian crops beat global emissions—even after 17 trips across the Atlantic

2025-08-14
Canadian-grown wheat, canola and peas have some of the lowest carbon footprints in the world—so low that, in some cases, they could be shipped to Europe 17 times before matching the emissions of the same crops grown there.  The study out of UBC Okanagan, published in Nature Food, compared the carbon footprints of these crops from Canada, France, Germany, Australia and the United States using the ISO 14067 standard.   Led by Dr. Nicole Bamber of UBCO’s Irving K. Barber Faculty of Science, the research ...

ORC2 regulation of human gene expression shows unexpected breadth and scale

2025-08-14
BIRMINGHAM, Ala. – Origin-recognition complex, or ORC, plays an unexpectedly broad role in the regulation of human cell gene expression, according to a study in the journal Cell Reports. “This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama at Birmingham Department of Genetics. “The unanticipated scale and breadth of the regulation opens new chapters in ORC biology.” The six-subunit complex was discovered ...

Researchers track how iron deficiency disrupts photosynthesis in crucial ocean algae

2025-08-14
The next time you breathe, consider this: photosynthesis of algae, powered by iron dust in the ocean, made it possible. Now, a new Rutgers University study published in the Proceedings of the National Academy of Sciences pulls back the curtain on this vital process. Iron is a critical micronutrient for marine phytoplankton, the microscopic algae that form the foundation of the ocean’s food webs. It is deposited into the world’s oceans as dust from deserts and arid areas as well as from glacial meltwater. “Every other breath you take includes oxygen from the ocean, ...

A Mount Sinai-Led team creates model for understanding how the brain’s decision-making is impacted in psychiatric disorders

2025-08-14
Scientists from the Icahn School of Medicine at Mount Sinai, working in collaboration with a team from the University of Texas at El Paso, have developed a novel computational framework for understanding how a region of the brain known as the striatum is involved in the everyday decisions we make and, importantly, how it might factor into impaired decision-making by individuals with psychiatric disorders like post-traumatic stress disorder and substance use disorder. In a study published in Nature Communications [10.1038/s41467-025-61466-x] on August 14, the team reported that modulating activity ...

A new way to study omega fatty acids

2025-08-14
Omega fatty acids are important to human health, including their role in metabolizing fats. Deviations in their position in a fatty acid chain can signal enzyme malfunctions or pathological metabolic processes, such as those occurring in cancer and autoimmune disorders. Now, researchers from UC San Diego and the University of Graz (Austria) have presented a new computational method to determine omega positions of lipids — the scientific term for fats — in complex biological samples including human tissues and blood. Until ...

LAST 30 PRESS RELEASES:

New CRISPR technique could rewrite future of genetic disease treatment

he new tech that could improve care for Parkinson's patients

Sharing is power: do the neighbourly thing when it comes to solar

Sparring saigas win 2025 BMC journals Image Competition

Researchers discover dementia-like behaviour in pre-cancer cells

Medical pros of electroconvulsive therapy (ECT) exaggerated while cons downplayed, survey findings suggest

Experts recommend SGLT-2 and GLP-1 diabetes drugs only for adults at moderate to higher risk of heart and kidney problems

Global study finds heart failure drug spironolactone fails to lower cardiovascular risk in dialysis patients

Deprivation and transport density linked to increased suicide risk in England

Flatworms can replace rats for breakthrough brain studies

Plastic from plants: FAMU-FSU College of Engineering professor uses material in plant cell walls to make versatile polymer

Leaders at Huntsman Cancer Institute drive theranostics expansion to transform cancer care

Thin films, big science: FSU chemists expand imaging possibilities with new X-ray material

66th Supplement to the Check-list of North American Birds publishes today in Ornithology

Canadian crops beat global emissions—even after 17 trips across the Atlantic

ORC2 regulation of human gene expression shows unexpected breadth and scale

Researchers track how iron deficiency disrupts photosynthesis in crucial ocean algae

A Mount Sinai-Led team creates model for understanding how the brain’s decision-making is impacted in psychiatric disorders

A new way to study omega fatty acids

Targeting ferroptosis in cancer stem cells: A promising approach to enhance cancer treatment

As the atmosphere changes, so will its response to geomagnetic storms

First transfer of behavior between species through single gene manipulation

A new network could help predict health problems in your pup

Connecting biofuel and conservation policies

Deep learning model successfully predicted ignition in inertial confinement fusion experiment

Maternal antibodies in breast milk regulate early immune responses in mouse gut

Densely planted maize communicates with neighboring plants to defend against pests

Paper: Decarbonize agriculture by expanding policies aimed at low-carbon biofuels

New tech speeds up AI training for drug discovery/disease research

Researchers synthesize a new allotrope of carbon

[Press-News.org] Deprivation and transport density linked to increased suicide risk in England