(Press-News.org) About The Study: Application of the Transparent Reporting of Observational Studies Emulating a Target Trial (TARGET) guideline recommendations aims to improve reporting transparency and peer review and help researchers, clinicians, and other readers interpret and apply the results.
Corresponding Author: To contact the corresponding author, James H. McAuley, PhD, email james.mcauley@unsw.edu.au.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.13350?guestAccessKey=6ad54c92-efdb-4815-8df4-2ed119c048a7&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=090325
# # #
Media advisory: This study is being presented at the 10th International Congress on Peer Review and Biomedical Publication. For more information on the Congress, go to peerreviewcongress.org.
END
Transparent Reporting of Observational Studies Emulating a Target Trial—The TARGET statement
JAMA
2025-09-03
ELSE PRESS RELEASES FROM THIS DATE:
Nonregistration, discontinuation, and nonpublication of randomized trials
2025-09-03
About The Study: Findings from this systematic review indicated that nonregistration, premature discontinuation due to poor recruitment, and nonpublication of randomized clinical trial (RCT) results remained major challenges, especially for non–industry-sponsored trials. To mitigate these challenges, requirements enforced by funders and ethics committees also taking into account legal obligations should be considered and empirically evaluated.
Corresponding Author: To contact the corresponding author, Matthias Briel, MD, PhD, email matthias.briel@usb.ch.
Embed this link to provide your readers free access to the full-text article This ...
Improving the reporting on health equity in observational research (STROBE-Equity)
2025-09-03
About The Study: Use of the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) -Equity extension alongside the STROBE statement when writing up completed reports of observational studies has the potential to advance the reporting of health equity data and considerations. Improved reporting of this information may help knowledge users better identify and apply evidence relevant to populations experiencing inequities.
Corresponding Author: To contact the corresponding author, Omar Dewidar, ...
Bacteria that ‘shine a light’ on microplastic pollution
2025-09-03
Microplastics are tiny, plastic fragments — many too small to see — found in the air, soil and water. Measuring their abundance in nature can direct cleanup resources, but current detection methods are slow, expensive or highly technical. Now, researchers publishing in ACS Sensors have developed a living sensor that attaches to plastic and produces green fluorescence. In an initial test on real-world water samples, the biosensor could easily detect environmentally relevant levels of microplastics.
Currently, scientists detect ...
SeoulTech develop hybrid polymer-CNT electrodes for safer brain-machine interfaces
2025-09-03
Brain–computer interfaces are technologies that enable direct communication between brain activity and external devices, enabling researchers to monitor and interpret brain signals in real time. These connections often involve arrays of tiny, hair-like electrodes called “microelectrodes” which are implanted within the brain to record or stimulate electrical activity. For decades, microelectrodes have faced a challenge in balancing conductivity with tissue compatibility. Rigid metal or silicon-based electrodes enable stable signal recordings but often damage the delicate brain tissues, whereas softer polymer electrodes reduce harm but suffer from poor signal transmission.
Bridging ...
From symptoms to biology: Neurodegeneration in paraventricular thalamus in bipolar disorder
2025-09-03
Bipolar disorder (BD) is a chronic mental health condition characterized by recurrent episodes of depression and mania. It poses a substantial burden on global health, with an increasing incidence. Despite its prevalence, there exists a significant gap in understanding the underlying neuropathological mechanisms. Although mitochondrial dysfunction has been implicated in BD, the specific brain region damaged is not yet fully understood. A deeper understanding is essential for advancing research efforts and developing ...
From longevity to cancer: Understanding the dual nature of polyamines
2025-09-03
Polyamines, a group of naturally occurring molecules found in all living organisms, are essential for fundamental cellular processes, such as growth and differentiation. In recent years, these compounds (particularly spermidine) have gained attention as promising ‘geroprotectors’ that promote healthy aging and extend lifespan. Studies have shown that polyamines can activate beneficial cellular processes like autophagy, which helps clear damaged cell components, primarily through a protein called eukaryotic translation initiation factor 5A (eIF5A1). However, these positive effects are overshadowed by a troubling paradox, as elevated polyamine levels are also consistently ...
Faraday Institution commits a further £9M to battery research to deliver commercial impact
2025-09-03
HARWELL, UK (3 September 2025) The Faraday Institution has announced a £9 million commitment to build on its application-inspired research programme to deliver the battery innovations of tomorrow.
The two new projects, that will begin in October 2025, include, for the first time, a Faraday Institution project to advance the scientific understanding of battery formation, ageing and testing -- a stage at the end of the battery manufacturing process. The project will aim to formulate new protocols to reduce battery manufacturing time and energy consumption in gigafactories.
This is the first of a number of new initiatives by the Faraday Institution ...
Study: Evaluating chatbot accuracy in the fast-changing blood cancer field
2025-09-03
MIAMI, FLORIDA (EMBARGOED UNTIL SEPT 3, 2025, AT 6:00 A.M. EDT) – Patients are increasingly turning to AI for medical information and even advice, but how should they approach using AI-powered services? A new study published Sept. 3 in the peer-reviewed journal, Future Science OA, provides insight into this question for the fast-moving field of blood cancer, evaluating the quality of responses by ChatGPT to a set of 10 medical questions.
The study investigated ChatGPT 3.5, a version of the popular chatbot from OpenAI that was freely available when the study was conducted, in July 2024. Four anonymous hematology-oncology physicians evaluated the answers.
ChatGPT 3.5 performed best ...
A ‘wasteful’ plant process makes a key prenatal vitamin. Climate change may reduce it.
2025-09-03
New research from Michigan State University reveals that photorespiration – long considered a wasteful process – is essential for producing a crucial nutrient for preventing birth defects.
For the first time, scientists have measured how much carbon flows through photorespiration to make folates, a class of compounds that includes vitamin B9 – known for its importance as a prenatal vitamin. According to the study, led by MSU researcher Berkley Walker, about 6 percent of the carbon absorbed by plants is used to make folates. That number plummets by fivefold when photorespiration is suppressed.
These findings, published in Nature Plants, could help scientists engineer ...
Targeted cell removal offers treatment hope
2025-09-03
A team of scientists at Kyoto University’s Institute for Integrated Cell-Material Sciences (iCeMS) has created a protein-based therapeutic tool that could change the way we treat diseases caused by harmful or unnecessary cells. The new tool, published in Nature Biomedical Engineering, involves a synthetic protein called Crunch, short for Connector for Removal of Unwanted Cell Habitat. Crunch uses the body’s natural waste removal system to clear out specific target cells, offering hope for improved treatments for cancer, autoimmune diseases, and other diseases where harmful cells cause damage.
Every day, billions of our body’s ...
LAST 30 PRESS RELEASES:
When tropical oceans were oxygen oases
Positive interactions dominate among marine microbes, six-year study reveals
Safeguarding the Winter Olympics-Paralympics against climate change
Most would recommend RSV immunizations for older and pregnant people
Donated blood has a shelf life. A new test tracks how it's aging
Stroke during pregnancy, postpartum associated with more illness, job status later
American Meteorological Society announces new executive director
People with “binge-watching addiction” are more likely to be lonely
Wild potato follows a path to domestication in the American Southwest
General climate advocacy ad campaign received more public engagement compared to more-tailored ad campaign promoting sustainable fashion
Medical LLMs may show real-world potential in identifying individuals with major depressive disorder using WhatsApp voice note recordings
Early translational study supports the role of high-dose inhaled nitric oxide as a potential antimicrobial therapy
AI can predict preemies’ path, Stanford Medicine-led study shows
A wild potato that changed the story of agriculture in the American Southwest
Cancer’s super-enhancers may set the map for DNA breaks and repair: A key clue to why tumors become aggressive and genetically unstable
Prehistoric tool made from elephant bone is the oldest discovered in Europe
Mineralized dental plaque from the Iron Age provides insight into the diet of the Scythians
Salty facts: takeaways have more salt than labels claim
When scientists build nanoscale architecture to solve textile and pharmaceutical industry challenges
Massive cloud with metallic winds discovered orbiting mystery object
Old diseases return as settlement pushes into the Amazon rainforest
Takeaways are used to reward and console – study
Velocity gradients key to explaining large-scale magnetic field structure
Bird retinas function without oxygen – solving a centuries-old biological mystery
Pregnancy- and abortion-related mortality in the US, 2018-2021
Global burden of violence against transgender and gender-diverse adults
Generative AI use and depressive symptoms among US adults
Antibiotic therapy for uncomplicated acute appendicitis
Childhood ADHD linked to midlife physical health problems
Patients struggle to measure blood pressure at home
[Press-News.org] Transparent Reporting of Observational Studies Emulating a Target Trial—The TARGET statementJAMA