GLP-1 RAs and cardiovascular and kidney outcomes by body mass index in type 2 diabetes

JAMA Network Open

2025-09-08

(Press-News.org) About The Study: In this cohort study of patients with type 2 diabetes, glucagon-like peptide-1 receptor agonists (GLP-1 RAs) use was associated with body mass index (BMI) -dependent cardiovascular benefits and consistent kidney protection, suggesting the importance of BMI stratification in guiding treatment decisions.

Corresponding Author: To contact the corresponding author, Ming-Lung Tsai, MD, email mltsai.cgmh@gmail.com.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2025.30952)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

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GLP-1 RAs and cardiovascular and kidney outcomes by body mass index in type 2 diabetes

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