Obesity treatment with bariatric surgery vs GLP-1 receptor agonists

JAMA Surgery

2025-09-17

(Press-News.org) About The Study: The findings of this study suggest that metabolic bariatric surgery was associated with more weight loss at lower ongoing costs compared with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in class II and III obesity. Further study is needed to determine if metabolic bariatric surgery should still be considered the last resort in treating obesity.

Corresponding Author: To contact the corresponding author, George M. Eid, MD, email george.eid@ahn.org.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamasurg.2025.3590)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Obesity treatment with bariatric surgery vs GLP-1 receptor agonists

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