Nicotinamide for skin cancer chemoprevention

JAMA Dermatology

2025-09-17

(Press-News.org) About The Study: The results of this cohort study suggest that there is a decreased risk of skin cancer among patients treated with nicotinamide, with the greatest effect seen when initiated after the first skin cancer. Nicotinamide is a vitamin B3 derivative that is sold as an over-the-counter medication. JAMA Dermatology Editor in Chief Kanade Shinkai, MD, PhD, selected the paper as a highlight for journalists. Once published, the paper will be accompanied by a podcast and short video.

Corresponding Author: To contact the corresponding author, Lee Wheless, MD, PhD, email lee.e.wheless@vumc.org.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamadermatol.2025.3238)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Nicotinamide for skin cancer chemoprevention

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