Reevaluating nonoperative management for pediatric uncomplicated acute appendicitis

JAMA Pediatrics

2025-10-05

(Press-News.org) About The Study: In contrast to earlier studies, this meta-analysis found significantly higher treatment failure and major complication rates within a year with nonoperative management among children and adolescents. The meta-analysis provides pediatricians and pediatric surgeons with up-to-date data to inform shared decision-making with families and encourage individualized, patient-centered treatment.

Corresponding Author: To contact the corresponding author, Isabella Faria, MD, email imdefrei@utmb.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamapediatrics.2025.4091)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Media advisory: This study is being presented at the American College of Surgeons Clinical Congress 2025.

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Reevaluating nonoperative management for pediatric uncomplicated acute appendicitis

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