Social adversity and triple-negative breast cancer incidence among black women

JAMA Network Open

2025-10-14

(Press-News.org) About The Study: This cohort study shows that high social adversity is associated with a high incidence of triple-negative breast cancer (TNBC) among Black women. As subtype is intrinsic to tumor development, these findings suggest an early and critical source of downstream breast cancer survival disparities. The findings of this study suggest potential social (epi)genomic and gene-environment interactions between social adversity and TNBC development in Black women.

Corresponding author: To contact the corresponding author, Neha Goel, M.D., M.P.H., email goeln1@mskcc.org.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi: 10.1001/jamanetworkopen.2025.37378)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

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