Targeted oxygen for initial resuscitation of preterm infants

JAMA

2025-12-10

(Press-News.org) About The Study: Initiating resuscitation of preterm infants with fraction of inspired oxygen of 0.6 vs 0.3 did not affect the risk of death or brain injury by 36 weeks’ corrected gestational age. These results lay a foundation for future trials evaluating the effectiveness and safety of using higher initial fraction of inspired oxygen levels for preterm infant resuscitation.

Corresponding Author: To contact the corresponding author, Ju Lee Oei, MD, email j.oei@uq.edu.au.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2025.23327)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Media advisory: This study is being presented at the Hot Topics in Neonatology 45th Annual Conference.

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