PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Lifestyle affects life expectancy more than genetics

2011-02-08
(Press-News.org) How long your parents lived does not affect how long you will live. Instead it is how you live your life that determines how old you will get, reveals research from the University of Gothenburg recently published in the Journal of Internal Medicine.

It is often assumed that people with parents who lived to be very old are more likely to live to a grand old age themselves. "But that's just not true – our study shows that hereditary factors don't play a major role and that lifestyle has the biggest impact," says professor emeritus Lars Wilhelmsen, referring to the 1913 Men study that formed the basis of the current research. Those who did not smoke, consumed moderate amounts of coffee and had a good socio-economic status at the age of 50 (measured in terms of housing costs), as well as good physical working capacity at the age of 54 and low cholesterol at 50 had the greatest chance of celebrating their 90th birthday.

"We're breaking new ground here," says Wilhelmsen. "Many of these factors have previously been identified as playing a role in cardiovascular disease, but here we are showing for the first time that they are important for survival in general." He believes that it is significant that the research illustrates so clearly that we do not "inherit" mortality to any great extent, but instead that it is the sum of our own habits that has the biggest impact. "The study clearly shows that we can influence several of the factors that decide how old we get," says Wilhelmsen. "This is positive not only for the individual, but also for society as it doesn't entail any major drug costs." The study has been published in the Journal of Internal Medicine.

The study of men born in 1913 The 1913 Men epidemiological study started up in 1963. A third of all male 50-year-olds in Gothenburg were called for a check-up that focused on cardiovascular health. Every ten years since, a new group of 50-year-olds has been called in and those who were already taking part in the study have been given another check-up. This has enabled researchers to follow the development of illnesses in a specific age group, and to compare the health of 50-year-olds in 2003 with that of 50-year-olds in 1963, for example. Women have also been included in the study since 2003. Several variables have been studied over the years, including BMI, smoking habits, cholesterol, exercise habits and blood pressure. The men born in 1913 were examined when they were 50, 54, 60, 67, 75 and 80. Of the 855 men who took part in the study from the start, 111 (13%) were still alive at the age of 90. Over the years the material has generated many research articles and doctoral theses. An interesting result came in 2008 when researchers were able to show that the drop in the number of smokers, combined with lower cholesterol levels and lower blood pressure, between 1963 and 2003 could offer an explanation for the marked downturn in the number of heart attacks during this 40-year period.

### END


ELSE PRESS RELEASES FROM THIS DATE:

Unexpected exoskeleton remnants found in Paleozoic fossils

2011-02-08
Washington, D.C.—Surprising new research shows that, contrary to conventional belief, remains of chitin-protein complex—structural materials containing protein and polysaccharide—are present in abundance in fossils of arthropods from the Paleozoic era. Previously the oldest molecular signature of chitin-protein complex was discovered in 25 million year old Cenozoic fossils and remnants of structural protein have also been discovered in 80 million-year-old Mesozoic fossils. Carnegie's George Cody and an international team of scientists discovered relicts of protein-chitin ...

Unexpected new mechanism behind rheumatoid arthritis

2011-02-08
A team of researchers at the University of Gothenburg, Sweden, has identified an enzyme that protects against inflammation and joint destruction. Made when the researchers blocked production of the enzyme GGTase-I in transgenic mice, this unexpected discovery could lead to the identification of new mechanisms that control the development of inflammatory disorders, as well as new medicines. The article has been published in the Journal of Clinical Investigation (JCI). GGTase-I is found in all cells but is particularly important for the function of so-called CAAX proteins ...

Brandeis study shows economic impact of dengue virus in Americas

2011-02-08
Dengue illness, the most common mosquito-borne viral disease in the world, has expanded from its Southeast Asian origins and is resurgent in countries such as Argentina, Chile and the continental United States. The economic burden of dengue (pronounced DENgee) in the Western Hemisphere, according to a new study from Brandeis University researchers published today in the American Journal of Tropical Medicine and Hygiene, is approximately $2.1 billion per year. This surpasses the loss from other viral illnesses on a country-by-country basis including human papillomavirus ...

Protein may be key to new treatment in a childhood cancer

2011-02-08
After analyzing hundreds of proteins produced by the DNA of tumor cells, researchers have identified one protein that may be central to a new treatment for the often-fatal childhood cancer neuroblastoma. Oncologists hope to translate the finding into pediatric clinical trials of a drug that blocks the protein's activity. "Our study implicates this protein as a promising treatment target for high-risk neuroblastoma," said pediatric oncologist Kristina A. Cole, M.D., Ph.D., of the Cancer Center at The Children's Hospital of Philadelphia. "The fact that drugs acting on this ...

A second pathway for antidepressants

A second pathway for antidepressants
2011-02-08
Using a unique and relatively simple cell-based fluorescent assay they developed, scientists with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC), Berkeley have identified a means by which fluoxetine, the active ingredient in Prozac, suppresses the activity of the TREK1 potassium channel. TREK1 activity has been implicated in mood regulation and could be an important target for fluoxetine and other antidepressant drugs. "Whereas the inhibiting of serotonin re-uptake remains fluoxetine's primary ...

Bad things seem even worse if people have to live through them again

2011-02-08
WASHINGTON — When people think unpleasant events are over, they remember them as being less painful or annoying than when they expect them to happen again, pointing to the power of expectation to help people brace for the worst, according to studies published by the American Psychological Association. In a series of eight studies exposing people to annoying noise, subjecting them to tedious computer tasks, or asking them about menstrual pain, participants recalled such events as being significantly more negative if they expected them to happen again soon. This reaction ...

Aluminum to replace copper as a conductor in on-board power systems

Aluminum to replace copper as a conductor in on-board power systems
2011-02-08
Electric power and electronics are playing an ever-increasing role in all kinds of vehicles. Currently copper is the conductive material of choice. But in comparison to aluminum copper is heavy and expensive. In particular for fully electric vehicles the switch to the cheaper and lighter aluminum would be an interesting option. That is why the optimization of intricate power supply networks is now in the focus of engineering research. Scientists from the Technische Universitaet Muenchen (TUM), in collaboration with BMW engineers, have now found out what tricks make it possible ...

Words help people form mathematical concepts

2011-02-08
Language may play an important role in learning the meanings of numbers, scholars at the University of Chicago report. A study based on research on deaf people in Nicaragua who never learned formal sign language showed that people who communicate using self-developed gestures, called homesigns, were unable to comprehend the value of numbers greater than three because they had not learned a language containing symbols used for counting. By contrast, deaf people who acquire conventional sign language as children can learn the meaning of large numbers. Researchers believe ...

Save messengers -- modified mRNAs open up new therapeutic possibilities

2011-02-08
Defects in the genome are the cause of many diseases. Gene therapy – direct replacement of mutant genes by intact DNA copies – offers a means of correcting such defects. Now a research team based at the Medical Center of the University of Munich, and led by Privatdozent Dr. Carsten Rudolph, has taken a new approach that avoids DNA delivery. The team shows for the first time that chemical modification of mRNAs (the metabolically active molecules derived from genomic DNA that programs protein synthesis) provides a promising alternative to DNA-based procedures. In contrast ...

New explanation for heart-healthy benefits of chocolate

2011-02-08
WASHINGTON, Feb. 7, 2011 — In time for the chocolate-giving and chocolate-noshing fest on Valentine's Day, scientists are reporting discovery of how this treat boosts the body's production of high-density lipoprotein cholesterol (HDL) — the "good" form of cholesterol that protects against heart disease. Just as those boxes of chocolates get hearts throbbing and mouths watering, polyphenols in chocolate rev up the activity of certain proteins, including proteins that attach to the genetic material DNA in ways that boost HDL levels. Their report appears in the Journal of ...

LAST 30 PRESS RELEASES:

Scientists unlock secrets behind flowering of the king of fruits

Texas A&M researchers illuminate the mysteries of icy ocean worlds

Prosthetic material could help reduce infections from intravenous catheters

Can the heart heal itself? New study says it can

Microscopic discovery in cancer cells could have a big impact

Rice researchers take ‘significant leap forward’ with quantum simulation of molecular electron transfer

Breakthrough new material brings affordable, sustainable future within grasp

How everyday activities inside your home can generate energy

Inequality weakens local governance and public satisfaction, study finds

Uncovering key molecular factors behind malaria’s deadliest strain

UC Davis researchers help decode the cause of aggressive breast cancer in women of color

Researchers discovered replication hubs for human norovirus

SNU researchers develop the world’s most sensitive flexible strain sensor

Tiny, wireless antennas use light to monitor cellular communication

Neutrality has played a pivotal, but under-examined, role in international relations, new research shows

Study reveals right whales live 130 years — or more

Researchers reveal how human eyelashes promote water drainage

Pollinators most vulnerable to rising global temperatures are flies, study shows

DFG to fund eight new research units

Modern AI systems have achieved Turing's vision, but not exactly how he hoped

Quantum walk computing unlocks new potential in quantum science and technology

Construction materials and household items are a part of a long-term carbon sink called the “technosphere”

First demonstration of quantum teleportation over busy Internet cables

Disparities and gaps in breast cancer screening for women ages 40 to 49

US tobacco 21 policies and potential mortality reductions by state

AI-driven approach reveals hidden hazards of chemical mixtures in rivers

Older age linked to increased complications after breast reconstruction

ESA and NASA satellites deliver first joint picture of Greenland Ice Sheet melting

Early detection model for pancreatic necrosis improves patient outcomes

Poor vascular health accelerates brain ageing

[Press-News.org] Lifestyle affects life expectancy more than genetics