PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Poorer patients have more severe ischemic strokes, study indicates

2011-02-10
(Press-News.org) CINCINNATI—Poorer patients have more severe ischemic strokes, or strokes resulting from blockages in blood vessels in the brain, according to new research from the University of Cincinnati (UC). A study led by Dawn Kleindorfer, MD, an associate professor in the department of neurology, found that increasing poverty in the neighborhood where the stroke patient lived was associated with worse stroke severity at presentation, independent of other known factors associated with stroke outcomes. The study is being presented Wednesday, Feb. 9, in Los Angeles at International Stroke Conference 2011, the annual meeting of the American Stroke Association. The research is part of the Greater Cincinnati/Northern Kentucky Stroke Study, begun in 1993 at the UC College of Medicine, which is funded by the National Institutes of Health (NIH) and identifies all hospitalized and autopsied cases of stroke and transient ischemic attack (TIA) in a five-county region. Researchers studied 1,933 cases of ischemic stroke from 2005, of which 21.9 percent of the patients were African-American and 52.3 percent were female, with an average overall patient age of 71. Researchers used community poverty levels based on census tract data to estimate individual socioeconomic status. The poorest community socioeconomic status was associated with a significantly increased initial stroke severity by 1.6 points on a severity scale compared with the richest category, researchers found. The analysis remained significant even after adjustment for demographics and other diseases. "The magnitude of change in stroke severity for the poorest patients was similar to the effect of having a history of coronary artery disease or high blood pressure," says Kleindorfer, a member of the UC Neuroscience Institute. Although this study cannot definitively say why poorer patients have more severe strokes, researchers suggest that socioeconomic status might impact stroke severity via access to care, cultural factors, medication compliance or undiagnosed disease states.

### END


ELSE PRESS RELEASES FROM THIS DATE:

Omega 3's -- more evidence for their benefit

2011-02-10
Omega-3 fatty acids –fats commonly found in fish oil – were shown several years ago to prevent retinopathy, a major form of blindness, in a mouse model of the disease. A follow-up study, from the same research team at Children's Hospital Boston, now reveals exactly how omega-3's provide protection, and provides reassurance that widely used COX-inhibiting drugs like aspirin and NSAIDs don't negate their benefit. The findings, published in the February 9th issue of Science Translational Medicine, also suggest that omega-3's may be beneficial in diabetes. Retinopathy – an ...

Researchers at Harvard and MITRE produce world's first programmable nanoprocessor

Researchers at Harvard and MITRE produce worlds first programmable nanoprocessor
2011-02-10
Cambridge, Mass. – February 9, 2011 – Engineers and scientists collaborating at Harvard University and the MITRE Corporation have developed and demonstrated the world's first programmable nanoprocessor. The groundbreaking prototype computer system, described in a paper appearing today in the journal Nature, represents a significant step forward in the complexity of computer circuits that can be assembled from synthesized nanometer-scale components. It also represents an advance because these ultra-tiny nanocircuits can be programmed electronically to perform a number ...

Searching for the soul of the genome

2011-02-10
VIDEO: Kelly Frazer, PhD, describes genome-wide association studies and the new CAD risk findings. Click here for more information. The discovery that a "gene desert" on chromosome 9 was a hotspot for coronary artery disease (CAD) risk was among the highlights of findings produced recently by genome-wide association studies, which compare the genomes of many people for genetic variations and have been broadly used in the past few years to study hundreds of diseases and complex ...

Skin cells help to develop possible heart defect treatment in first-of-its-kind Stanford study

2011-02-10
STANFORD, Calif. — Using skin cells from young patients who have a severe genetic heart defect, Stanford University School of Medicine scientists have generated beating heart cells that carry the same genetic mutation. The newly created human heart cells — cardiomyocytes — allowed the researchers for the first time to examine and characterize the disorder at the cellular level. In a study to be published online Feb. 9 in Nature, the investigators also report their identification of a promising drug to reverse the heart malfunction — for which there are currently no decent ...

Human and mouse studies sharpen focus on cause of celiac disease

2011-02-10
Blocking a factor that can activate the human immune response against intestinal bacteria or certain foods could prevent the development of celiac disease in those most at risk, researchers report in the journal Nature. The study, to be published early online Feb. 9, points to two chemical signals—interleukin 15 and retinoic acid, a derivative of vitamin A—as triggers for the inflammatory response to gluten, a protein found in many grains that causes celiac disease. "We found that having elevated levels of IL-15 in the gut could initiate all the early stages of celiac ...

Researchers find public sector research responsible for many new drug discoveries

2011-02-10
(Boston) - Researchers from Boston University School's of Medicine (BUSM), Management (SMG) and Law (LAW), along with collaborators from the National Institutes of Health, believe that public-sector research has had a more immediate effect on improving public health than was previously realized. The findings, which appear as a Special Article in the February 10th issue of The New England Journal of Medicine, have economic and policy implications. Historically, public sector research institutions (PSRI) have not participated in any major way in the downstream, applied ...

Scientists discover gene regulation mechanism unique to primates

2011-02-10
Scientists have discovered a new way genes are regulated that is unique to primates, including humans and monkeys. Though the human genome – all the genes that an individual possesses – was sequenced 10 years ago, greater understanding of how genes function and are regulated is needed to make advances in medicine, including changing the way we diagnose, treat and prevent a wide range of diseases. "It's extremely valuable that we've sequenced a large bulk of the human genome, but sequence without function doesn't get us very far, which is why our finding is so important," ...

Scripps Research study presents surprising view of brain formation

2011-02-10
LA JOLLA, CA – Embargoed by the journal Neuron until February 9, 2011, noon, Eastern time – A study from The Scripps Research Institute has unveiled a surprising mechanism that controls brain formation. The findings have implications for understanding a host of diseases, including some forms of mental retardation, epilepsy, schizophrenia, and autism. The research, led by Scripps Research Professor Ulrich Mueller, was published in the journal Neuron on February 10, 2011. In the new study, Mueller and colleagues focused on a protein called reelin. They found reelin is ...

Fetal surgery, pioneered at UCSF, is more effective than operating after birth

2011-02-10
Thirty years ago, the first human fetal surgery was performed at the University of California, San Francisco. Now, a randomized controlled trial has proven definitively that fetal surgery can help certain patients before birth. Babies who undergo an operation to repair the birth defect spina bifida while still in the womb develop better and experience fewer neurologic complications than babies who have corrective surgery after birth, according to findings from a major multicenter trial led by UCSF researchers. The study is the first to systematically evaluate the best ...

New hybrid drug, derived from common spice, may protect, rebuild brain cells after stroke

2011-02-10
LOS ANGELES (EMBARGOED UNTIL FEB. 9, 2011 AT 9:15 PM EST) – Whether or not you're fond of Indian, Southeast Asian and Middle Eastern food, stroke researchers at Cedars-Sinai Medical Center think you may become a fan of one of their key spices. The scientists created a new molecule from curcumin, a chemical component of the golden-colored spice turmeric, and found in laboratory experiments that it affects mechanisms that protect and help regenerate brain cells after stroke. Research scientist Paul A. Lapchak, Ph.D., director of Translational Research in the Department ...

LAST 30 PRESS RELEASES:

Natural supplement may decrease biological aging and improve muscle strength

Ursolic acid modulates estrogen conversion to relieve inflammation in metabolic dysfunction-associated steatotic liver disease via HSD17B14

New research highlights how parental awe and pride enhance well-being

Protecting audio privacy at the source

Omnivorous? Vegan? Makes no difference to muscle building after weight training, study finds

More ticks carry Lyme disease bacteria in pheasant-release areas

Older adults respond well to immunotherapy despite age-related immune system differences

Study reveals new genetic mechanism behind autism development

The puberty talk: Parents split on right age to talk about body changes with kids

Tusi (a mixture of ketamine and other drugs) is on the rise among NYC nightclub attendees

Father’s mental health can impact children for years

Scientists can tell healthy and cancerous cells apart by how they move

Male athletes need higher BMI to define overweight or obesity

How thoughts influence what the eyes see

Unlocking the genetic basis of adaptive evolution: study reveals complex chromosomal rearrangements in a stick insect

Research Spotlight: Using artificial intelligence to reveal the neural dynamics of human conversation

Could opioid laws help curb domestic violence? New USF research says yes

NPS Applied Math Professor Wei Kang named 2025 SIAM Fellow

Scientists identify agent of transformation in protein blobs that morph from liquid to solid

Throwing a ‘spanner in the works’ of our cells’ machinery could help fight cancer, fatty liver disease… and hair loss

Research identifies key enzyme target to fight deadly brain cancers

New study unveils volcanic history and clues to ancient life on Mars

Monell Center study identifies GLP-1 therapies as a possible treatment for rare genetic disorder Bardet-Biedl syndrome

Scientists probe the mystery of Titan’s missing deltas

Q&A: What makes an ‘accidental dictator’ in the workplace?

Lehigh University water scientist Arup K. SenGupta honored with ASCE Freese Award and Lecture

Study highlights gaps in firearm suicide prevention among women

People with medical debt five times more likely to not receive mental health care treatment

Hydronidone for the treatment of liver fibrosis associated with chronic hepatitis B

Rise in claim denial rates for cancer-related advanced genetic testing

[Press-News.org] Poorer patients have more severe ischemic strokes, study indicates