Eyes of cattle may become new windows to detect mad cow disease
2010-09-08
(Press-News.org) The eyes may or may not be windows to the soul, as the old adage goes, but scientists are reporting evidence that a peek into the eyes of cattle may become the basis for a long-sought test to detect infection with the agent that causes Mad Cow Disease. That test could help prevent the disease from spreading in the food supply. A study on using the tell-tale glow given off by eyes infected with the Mad Cow agent appears in ACS' semi-monthly journal Analytical Chemistry.
Jacob Petrich and colleagues note that the human form of Mad Cow Disease is linked to eating beef from animals infected with abnormal proteins called prions implicated in a range of brain diseases. Scientists are trying to develop tests to detect infected cattle before they enter the food supply. Past studies suggest that chemical changes in an animal's retina, the light sensitive nerve tissue in the back of the eye, may provide a basis for detecting prion diseases.
The scientists showed that retinas of sheep infected with scrapie, a disease similar to Mad Cow Disease, emit a characteristic glow when examined with a beam of light from a special instrument. They suggest that eye tests based on the finding could become important in the future for fast, inexpensive diagnosis of prion diseases and other neurological diseases.
INFORMATION:
ARTICLE FOR IMMEDIATE RELEASE
"Fluorescence Spectroscopy of the Retina for Diagnosis of Transmissible Spongiform Encephalopathies"
DOWNLOAD FULL TEXT ARTICLE
http://pubs.acs.org/stoken/presspac/presspac/full/10.1021/ac100179u
CONTACT:
Jacob Petrich, Ph.D.
Department of Chemistry
Iowa State University
Ames, Iowa 50011
Phone: 515-294-9422
Fax: 515-294-0105
Email: jwp@iastate.edu
END
ELSE PRESS RELEASES FROM THIS DATE:
2010-09-08
The formaldehyde added to fabrics to keep clothing looking fresh and wrinkle-free is unlikely to pose a health risk to consumers, according to an article in the current issue of Chemical & Engineering News (C&EN), ACS' weekly newsmagazine.
C&EN Senior Correspondent David J. Hanson notes that manufacturers have added formaldehyde to fabrics for almost a hundred years to make fabrics easier to care for, particularly to reduce wrinkling in cotton and prevent stains. But concern has emerged over formaldehyde's potential for causing allergic reactions such as skin rashes ...
2010-09-08
High testosterone levels in CEOs negotiating mergers and acquisitions are linked to a higher rate of dropped deals and an increase in hostile takeover attempts, according to a new study in the current issue of Management Science, a journal of the Institute for Operations Research and the Management Sciences (INFORMS®).
"Deal or No Deal: Hormones and the Mergers and Acquisitions Game" is by Maurice Levi, Kai Li, and Feng Zhang of the Sauder School of Business at the University of British Columbia. The study appears in the current issue of Management Science.
A podcast ...
2010-09-08
Elimination of a molecular gatekeeper leads to the development of arthritis in mice, scientists report in a study published in the Journal of Experimental Medicine. The newly discovered gatekeeper is a protein that determines the fate – survival or death – of damaging cells that mistakenly attack the body's own tissues and lead to autoimmune disorders such as arthritis.
Better understanding how arthritis develops will offer scientists an opportunity to explore new types of treatments for patients whose arthritis has not been effectively treated with current therapies.
"This ...
2010-09-08
JUPITER, FL, September 8, 2010 – A team led by a Scripps Research Institute scientist has for the first time identified a new gene that is required for memory formation in Drosophila, the common fruit fly. The gene may have similar functions in humans, shedding light on neurological disorders such as Alzheimer's disease or human learning disabilities.
The study was published in the September 9, 2010 edition (Vol. 67, No. 5) of the journal Neuron.
"This is the first time we have a new memory and learning gene that lies outside what has been considered the most fundamental ...
2010-09-08
COLUMBUS, Ohio – The wasting disease associated with some cancers that is typically seen affecting skeletal muscles can also cause significant damage to the heart, new research in mice suggests.
Before now, cachexia, characterized by muscle wasting and dramatic weight loss, was believed to spare the heart. But an Ohio State University study showed that the condition reduces heart function and changes the heart muscle structure in mice with colon cancer.
Previous studies have suggested that cachexia is responsible for between one-fifth and one-third of all cancer deaths. ...
2010-09-08
COLUMBUS, Ohio – Almost three out of four cats in a new study wore collars consistently during a six-month study, suggesting that most cats will tolerate a collar even if their owners are skeptical about its success.
In fact, in almost 60 percent of cases, the animals' tolerance of collars exceeded owners' expectations that their cat would keep the collar on without much trouble.
The researchers suggest that, armed with this data, veterinarians should include a discussion about the importance of identification during annual wellness exams of pet cats. They also say ...
2010-09-08
Two opportunistic pathogens that were once thought to be very different have evolved some sexual reproduction and disease-causing habits that are not only similar but also suggest that in the microbial world sex and virulence are closely linked, according to a review published this week in the online journal mBio™.
"Although the mechanisms used by bacterial and fungal species to promote genetic exchange are distinct, recent studies have uncovered surprising parallels between pheromone signaling in these species," says Richard Bennett of Brown University who co-authored ...
2010-09-08
Obesity and infertility frequently go hand in hand. Now, researchers reporting on studies of mice in the September issue of Cell Metabolism, a Cell Press publication, might have figured out why that is, and the results come as something of a surprise.
"There was a sense that the reproductive dysfunction was due to insulin resistance," said Andrew Wolfe of Hopkins Children's. "What we propose is a fundamentally new model showing that different tissues respond to obesity differently and that while cells in the liver and muscle become insulin resistant, cells in the pituitary ...
2010-09-08
New findings reported in the September issue of Cell Metabolism, a Cell Press publication, appear to explain why people who carry specific and common versions of a single gene are more likely to have high cholesterol and to suffer a heart attack. Studies in mice show that the gene, known as sortilin (SORT1), controls the release of LDL (a.k.a. "bad") cholesterol from the liver into the bloodstream.
The findings suggest that SORT1 may be a good target for new cholesterol-lowering drugs, according to the researchers.
"The vast majority – some 95 percent -- of cardiovascular ...
2010-09-08
In children with wrist fractures, a splint is as effective as a cast and provides greater comfort and easier hygiene, found a study published in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj100119.pdf.
Distal radius fractures — wrist fractures — are the most common break in children and a frequent reason for emergency department visits. The usual treatment is a short arm cast for four to six weeks with follow up visits to an orthopaedic surgeon.
The study, a randomized controlled trial with 92 children aged 5 to ...
LAST 30 PRESS RELEASES:
[Press-News.org] Eyes of cattle may become new windows to detect mad cow disease