PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Collaborative care shown to be successful for patients with opioid addictions

2011-03-15
(Press-News.org) (Boston) - Researchers from Boston University School of Medicine (BUSM) have found that for the majority of patients with opioid addiction, collaborative care with nurse care managers is a successful method of service delivery while effectively utilizing the time of physicians prescribing buprenorphine. The findings, which appear in the March 14 issue of the Archives of Internal Medicine, serve as a model of service delivery for facilitating access and improving outcomes in patients with opioid addiction.

Opioid addiction is a chronic, relapsing brain disease that affects millions of Americans and places a tremendous burden on the healthcare system. Recent studies have revealed alarming increases in opioid addiction and overdoses, particularly with regard to prescription opioids. Less than 25 percent of individuals addicted to opioids receive addiction treatment.

In 2002, US physicians gained the opportunity to treat opioid-addicted patients with buprenorphine in primary care settings, commonly referred to as office-based opioid treatment (OBOT). Although OBOT has been shown to be effective in primary care settings, it remains underutilized in traditional care models mainly due to the lack of adequate clinical support given the additional needs for patient monitoring.

From 2003 to 2008, 408 patients with opioid addiction were treated with buprenorphine utilizing collaborative care between nurse care managers and generalist physicians. At 12 months, 51 percent of patients (196/382) underwent successful treatment. Of patients remaining in treatment at three, six, nine and 12 months, 93 percent were no longer using illicit opioids or cocaine based on urine drug tests.

"These outcomes were achieved with a model that facilitated physician involvement," said lead author Daniel P. Alford, MD, MPH, FACP, FASAM, an associate professor of medicine at BUSM.

"Our study shows that in this particular setting, collaboration with nurse care managers allowed academic generalist physicians with research, administrative and clinical responsibilities to effectively and safely treat a large number of patients, many of whom had complex psychosocial needs," he added.

According to the researchers this study adds to the growing body of evidence that office-based treatment of opioid addiction is feasible in primary care settings.

### Funding for this study was provided by the Massachusetts Department of Public Health.


ELSE PRESS RELEASES FROM THIS DATE:

An inside look at how the elite control HIV

2011-03-15
In the years since the AIDS epidemic began, it has become clear that there is substantial variation in the way that individuals respond to HIV infection. Although most progress quickly from initial infection to immunodeficiency, a small subset survive for long periods without developing symptoms. These patients, dubbed elite controllers, display undetectable levels of viral replication, but the mechanism that explains how their immune systems effectively control the virus is not understood. In this paper, Mathias Lichterfeld and colleagues, at Massachusetts General Hospital ...

New mouse model explains common pediatric brain tumor

2011-03-15
Pilocytic astrocytoma (PA) is the most common pediatric brain tumor, and there are few medical therapies available to those patients for whom surgery is not curative. However, it has been difficult to design targeted PA therapies because the cellular mechanisms that lead to the cancer are incompletely understood, and there is no animal model of the disease. Recent work has suggested that activation of a particular cell signaling pathway may be required for PA formation, and mutations in one gene in that pathway, a kinase called BRAF, are found in more than half of all ...

JCI online early table of contents: March 14, 2011

2011-03-15
EDITOR'S PICK An inside look at how the elite control HIV In the years since the AIDS epidemic began, it has become clear that there is substantial variation in the way that individuals respond to HIV infection. Although most progress quickly from initial infection to immunodeficiency, a small subset survive for long periods without developing symptoms. These patients, dubbed elite controllers, display undetectable levels of viral replication, but the mechanism that explains how their immune systems effectively control the virus is not understood. In this paper, Mathias ...

Tumor suppressor blocks viral growth in natural HIV controllers

2011-03-15
Elevated levels of p21, a protein best known as a cancer fighter, may be involved in the ability of a few individuals to control HIV infection with their immune system alone. In a paper in the April edition of the Journal of Clinical Investigation, researchers from the Massachusetts General Hospital (MGH) Infectious Disease Division and the Ragon Institute of MGH, MIT and Harvard report that CD4 T cells from HIV controllers, while capable of being infected, can effectively suppress key aspects of the viral life cycle, an ability that may be associated with increased expression ...

Seedlings thrive with distant relatives, seeds with close family

2011-03-15
A variety of plant seedlings suffer most from competition when planted with close relatives, and grow best when planted alongside distant relatives in field soils, researchers from Case Western Reserve University and the University of California, Davis, have found. And, when seeds of the same species are buried among relatives in the field, the seeds germinate at a higher rate and grow better early in life in close relatives' habitats than distant relatives' habitats. The work will be published in the Proceedings of the National Academy of Sciences March 14. The findings, ...

Rock-paper-scissors tournaments explain ecological diversity

2011-03-15
According to classical ecology, when two species compete for the same resource, eventually the more successful species will win out while the other will go extinct. But that rule cannot explain systems such as the Amazon, where thousands of tree species occupy similar ecological niches. The childhood game of rock-paper-scissors provides one solution to this puzzle, report researchers at the University of Chicago and the University of California, Santa Barbara in Proceedings of the National Academy of Sciences. A mathematical model designed around the game's dynamics produced ...

Seedless cherimoya, the next banana?

2011-03-15
Mark Twain called it "the most delicious fruit known to man." But the cherimoya, or custard apple, and its close relations the sugar apple and soursop, also have lots of big, awkward seeds. Now new research by plant scientists in the United States and Spain could show how to make this and other fruits seedless. Going seedless could be a big step for the fruit, said Charles Gasser, professor of plant biology at UC Davis. "This could be the next banana -- it would make it a lot more popular," Gasser said. Bananas in their natural state have up to a hundred seeds; all ...

Benefits of bariatric surgery may outweigh risks for severely obese

2011-03-15
Bariatric surgery can result in long-term weight loss and significant reductions in cardiac and other risk factors for some severely obese adults, according to a scientific statement from the American Heart Association. The statement, published in Circulation: Journal of the American Heart Association, is the first by the American Heart Association focused solely on bariatric surgery and cardiac risk factors, according to lead author Paul Poirier, M.D., Ph.D., director of the prevention/rehabilitation program at Quebec Heart and Lung Institute at Laval University ...

Natural compounds: the future of anti-malarial treatment

2011-03-15
In the run up to World Malaria Day on the 25th April 2011, BioMed Central's open access journal Malaria Journal takes a long hard look at the development of natural compounds for use in the fight against malaria. There are over 200 million cases of malaria each year with 85% of all cases being children under five years old and, according to the World Health Organisation, in 2009 malaria was responsible for 781,000 deaths worldwide. Low cost treatment is available, 100 million children a year are treated with Artemisinin combination therapy at a cost of about 30 cents ...

'Ivory wave' may be new legal high after 'miaow miaow' (mephedrone) ban

2011-03-15
A new legal high has emerged that seems to be replacing the banned substance mephedrone or "miaow miaow", warns a critical care paramedic in Emergency Medicine Journal. Mephedrone was banned in England, when it was reclassified as a class B drug in April 2010. The new drug in circulation is "ivory wave," also known as "purple wave," "ivory coast," or "vanilla sky." And its use has already been implicated in hospital admissions and deaths in various parts of England, says the author. Ivory wave is usually sold online as bath salts in packets of between 200 and 500 ...

LAST 30 PRESS RELEASES:

Youngest in class at higher risk of mental health problems

American Heart Association announces new volunteer leaders for 2025-26

Gut microbiota analysis can help catch gestational diabetes

FAU’s Paulina DeVito awarded prestigious NSF Graduate Research Fellowship

Champions for change – Paid time off initiative just made clinical trials participation easier

Fentanyl detection through packaging

Prof. Eran Meshorer elected to EMBO for pioneering work in epigenetics

New 3D glacier visualizations provide insights into a hotter Earth

Creativity across disciplines

Consequences of low Antarctic sea ice

Hear here: How loudness and acoustic cues help us judge where a speaker is facing

A unique method of rare-earth recycling can strengthen the raw material independence of Europe and America

Epilepsy self-management program shows promise to control seizures, improve mood and quality of life

Fat may play an important role in brain metabolism

New study finds no lasting impact of pandemic pet ownership on human well-being

New insights on genetic damage of some chemotherapies could guide future treatments with less harmful side effects

Gut microbes could protect us from toxic ‘forever chemicals’

Novel modelling links sea ice loss to Antarctic ice shelf calving events

Scientists can tell how fast you're aging from a single brain scan

U.S. uterine cancer incidence and mortality rates expected to significantly increase by 2050

Public take the lead in discovery of new exploding star

What are they vaping? Study reveals alarming surge in adolescent vaping of THC, CBD, and synthetic cannabinoids

ECMWF - delivering forecasts over 10 times faster and cutting energy usage by 1000

Brazilian neuroscientist reveals how viral infections transform the brain through microscopic detective work

Turning social fragmentation into action through discovering relatedness

Cheese may really be giving you nightmares, scientists find

Study reveals most common medical emergencies in schools

Breathable yet protective: Next-gen medical textiles with micro/nano networks

Frequency-engineered MXene supercapacitors enable efficient pulse charging in TENG–SC hybrid systems

Developed an AI-based classification system for facial pigmented lesions

[Press-News.org] Collaborative care shown to be successful for patients with opioid addictions