PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Depression, age, other factors linked to dependence after stroke

2011-03-15
(Press-News.org) ST. PAUL, Minn. – People who have a stroke are more likely to be dependent if they are depressed, older or have other medical problems, according to a study published in the March 15, 2011, print issue of Neurology®, the medical journal of the American Academy of Neurology.

"Post-stroke depression is a common problem. About 795,000 people in the United States have a stroke each year and one third of survivors develop depression as a result," said study author Arlene Schmid, PhD, OTR, with the Richard L. Roudebush Veterans Affairs Medical Center and Indiana University in Indianapolis. "We wanted to see whether depression and other factors affected function and dependence after a stroke."

For the study, researchers gathered information about 367 ischemic stroke survivors with an average age of 62 with no severe language or thinking skill impairments. Of those, 174 were diagnosed with post-stroke depression one month after the stroke.

The participant's level of independence was rated using a zero to five scale, with five being the most severely disabled and dependent. Three months later, 20 percent of participants were considered dependent, scoring a level three or higher.

The study found that stroke survivors with depression were more likely to be dependent if they were older, had other coinciding health problems or were severely depressed compared to those who were younger (64 vs. 59), free of other health problems (18 vs. 15 points on a test for co-morbidities) or not depressed (16 vs. 14 points on a patient health questionnaire).

The study did not determine whether improvement in depression helped people with recovering their independence after three months. "Even if the treatment and improvement of post-stroke depression does not directly influence recovery, it is extremely important for depression to be identified and treated since it is associated with other health and social problems," Schmid said.

###The study was supported by the National Institutes of Health and the National Institute of Neurological Disorders and Stroke.

The American Academy of Neurology, an association of more than 22,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as epilepsy, dystonia, migraine, Huntington's disease, and dementia.

For more information about the American Academy of Neurology, visit http://www.aan.com.

VIDEO:
http://www.youtube.com/AANChannel

TEXT:
http://www.aan.com/press

TWEETS:
http://www.twitter.com/AANPublic

END



ELSE PRESS RELEASES FROM THIS DATE:

Study identifies therapeutic target for liver cancer and predictive biomarker of response

2011-03-15
Cold Spring Harbor, N.Y – In a research study appearing in the journal Cancer Cell on March 14, scientists from Cold Spring Harbor Laboratory (CSHL) and four other institutions have identified a strategy for targeted molecular therapy in liver cancer, which currently has limited treatment options and one of the worst one-year survival rates of any cancer type. The researchers' experiments reveal that up to 15% of liver tumors are "driven" by the hyperactivity of a gene called FGF19, which is well known for its role in various normal biological processes such as cell growth ...

Collaborative care shown to be successful for patients with opioid addictions

2011-03-15
(Boston) - Researchers from Boston University School of Medicine (BUSM) have found that for the majority of patients with opioid addiction, collaborative care with nurse care managers is a successful method of service delivery while effectively utilizing the time of physicians prescribing buprenorphine. The findings, which appear in the March 14 issue of the Archives of Internal Medicine, serve as a model of service delivery for facilitating access and improving outcomes in patients with opioid addiction. Opioid addiction is a chronic, relapsing brain disease that affects ...

An inside look at how the elite control HIV

2011-03-15
In the years since the AIDS epidemic began, it has become clear that there is substantial variation in the way that individuals respond to HIV infection. Although most progress quickly from initial infection to immunodeficiency, a small subset survive for long periods without developing symptoms. These patients, dubbed elite controllers, display undetectable levels of viral replication, but the mechanism that explains how their immune systems effectively control the virus is not understood. In this paper, Mathias Lichterfeld and colleagues, at Massachusetts General Hospital ...

New mouse model explains common pediatric brain tumor

2011-03-15
Pilocytic astrocytoma (PA) is the most common pediatric brain tumor, and there are few medical therapies available to those patients for whom surgery is not curative. However, it has been difficult to design targeted PA therapies because the cellular mechanisms that lead to the cancer are incompletely understood, and there is no animal model of the disease. Recent work has suggested that activation of a particular cell signaling pathway may be required for PA formation, and mutations in one gene in that pathway, a kinase called BRAF, are found in more than half of all ...

JCI online early table of contents: March 14, 2011

2011-03-15
EDITOR'S PICK An inside look at how the elite control HIV In the years since the AIDS epidemic began, it has become clear that there is substantial variation in the way that individuals respond to HIV infection. Although most progress quickly from initial infection to immunodeficiency, a small subset survive for long periods without developing symptoms. These patients, dubbed elite controllers, display undetectable levels of viral replication, but the mechanism that explains how their immune systems effectively control the virus is not understood. In this paper, Mathias ...

Tumor suppressor blocks viral growth in natural HIV controllers

2011-03-15
Elevated levels of p21, a protein best known as a cancer fighter, may be involved in the ability of a few individuals to control HIV infection with their immune system alone. In a paper in the April edition of the Journal of Clinical Investigation, researchers from the Massachusetts General Hospital (MGH) Infectious Disease Division and the Ragon Institute of MGH, MIT and Harvard report that CD4 T cells from HIV controllers, while capable of being infected, can effectively suppress key aspects of the viral life cycle, an ability that may be associated with increased expression ...

Seedlings thrive with distant relatives, seeds with close family

2011-03-15
A variety of plant seedlings suffer most from competition when planted with close relatives, and grow best when planted alongside distant relatives in field soils, researchers from Case Western Reserve University and the University of California, Davis, have found. And, when seeds of the same species are buried among relatives in the field, the seeds germinate at a higher rate and grow better early in life in close relatives' habitats than distant relatives' habitats. The work will be published in the Proceedings of the National Academy of Sciences March 14. The findings, ...

Rock-paper-scissors tournaments explain ecological diversity

2011-03-15
According to classical ecology, when two species compete for the same resource, eventually the more successful species will win out while the other will go extinct. But that rule cannot explain systems such as the Amazon, where thousands of tree species occupy similar ecological niches. The childhood game of rock-paper-scissors provides one solution to this puzzle, report researchers at the University of Chicago and the University of California, Santa Barbara in Proceedings of the National Academy of Sciences. A mathematical model designed around the game's dynamics produced ...

Seedless cherimoya, the next banana?

2011-03-15
Mark Twain called it "the most delicious fruit known to man." But the cherimoya, or custard apple, and its close relations the sugar apple and soursop, also have lots of big, awkward seeds. Now new research by plant scientists in the United States and Spain could show how to make this and other fruits seedless. Going seedless could be a big step for the fruit, said Charles Gasser, professor of plant biology at UC Davis. "This could be the next banana -- it would make it a lot more popular," Gasser said. Bananas in their natural state have up to a hundred seeds; all ...

Benefits of bariatric surgery may outweigh risks for severely obese

2011-03-15
Bariatric surgery can result in long-term weight loss and significant reductions in cardiac and other risk factors for some severely obese adults, according to a scientific statement from the American Heart Association. The statement, published in Circulation: Journal of the American Heart Association, is the first by the American Heart Association focused solely on bariatric surgery and cardiac risk factors, according to lead author Paul Poirier, M.D., Ph.D., director of the prevention/rehabilitation program at Quebec Heart and Lung Institute at Laval University ...

LAST 30 PRESS RELEASES:

Zidesamtinib shows durable responses in ROS1 TKI pre-treated NSCLC, including patients with CNS disease and ROS1 G2032R mutations

Crizotinib fails to improve disease-free survival in resected early-stage ALK+ NSCLC

Ivonescimab plus chemotherapy improves progression-free survival in patients with EGFR+ NSCLC following 3rd-generation EGFR-TKI therapy

FLAURA2 trial shows osimertinib plus chemotherapy improves overall survival in eGFR-mutated advanced NSCLC

Aumolertinib plus chemotherapy improves progression-free survival in NSCLC with EGFR and concomitant tumor suppressor genes: ACROSS 2 phase III study

New antibody-drug conjugate shows promising efficacy in EGFR-mutated NSCLC patients

Iza-Bren in combination with osimertinib shows 100% response rate in EGFR-mutated NSCLC, phase II study finds

COMPEL study shows continuing osimertinib treatment through progression with the addition of chemotherapy improves progression-free survival in EGFR-mutated NSCLC

CheckMate 77T: Nivolumab maintains quality of life and reduces symptom deterioration in resectable NSCLC

Study validates AI lung cancer risk model Sybil in predominantly Black population at urban safety-net hospital

New medication lowered hard-to-control high blood pressure in people with chronic kidney disease

Innovative oncolytic virus and immunotherapy combinations pave the way for advanced cancer treatment

New insights into energy metabolism and immune dynamics could transform head and neck cancer treatment

Pennington Biomedical’s Dr. Steven Heymsfield named LSU Boyd Professor – LSU’s highest faculty honor

Study prompts new theory of human-machine communication

New method calculates rate of gene expression to understand cell fate

Researchers quantify rate of essential evolutionary process in the ocean

Innovation Crossroads companies join forces, awarded U.S. Air Force contract

Using new blood biomarkers, USC researchers find Alzheimer’s disease trial eligibility differs among various populations

Pioneering advances in in vivo CAR T cell production

Natural medicines target tumor vascular microenvironment to inhibit cancer growth

Coral-inspired pill offers a new window into the hidden world of the gut

nTIDE September2025 Jobs Report: Employment for people with disabilities surpasses prior high

When getting a job makes you go hungry

Good vibrations could revolutionize assisted reproductive technology

More scrutiny of domestic fishing fleets at ports could help deter illegal fishing

Scientists transform plastic waste into efficient CO2 capture materials

Discovery of North America’s role in Asia’s monsoons offers new insights into climate change

MD Anderson and Phoenix SENOLYTIX announce strategic cross-licensing agreement to enhance inducible switch technologies for cell and gene therapies

Researchers discover massive geo-hydrogen source to the west of the Mussau Trench

[Press-News.org] Depression, age, other factors linked to dependence after stroke