(Press-News.org) Patients who receive intensive care services are very different in the United States than in the United Kingdom, according to a new study that compared admission and mortality statistics from ICUs in each country. The study found that U.K. patients are much sicker upon ICU admission, whereas U.S. patients are more likely to require continuing care after discharge and are often sent to skilled care facilities instead of home.
"The U.S. has about seven times as many ICU beds available per capita than the U.K. We wanted to compare the two because they represent extremes of ICU availability in developed countries," said lead author, Hannah Wunsch, MD, assistant professor of anesthesiology and epidemiology at Columbia University. "We wanted to look at the effect of that different availability of care to understand what impact that has on the delivery of critical care. What happens when you are on those extremes?"
Their findings are published online ahead of the print edition of the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. Read the full study here.
Dr. Wunsch and colleagues examined data from Project IMPACT (PI) in the U.S., and Case Mix Programme (CMP) in the U.K., both large prospective datasets abstracted from clinical records of voluntarily participating ICUs by trained data collectors, according to precise rules and definitions. The researchers merged the datasets and used variables that were confirmed to be defined similarly in both countries.
They analyzed all medical admissions to ICUs from 2002 to 2004, excluding surgical admissions, patients younger than 16 years, and readmissions to the ICU during the same hospital stay.
The researchers then calculated the relative degree of illness of patients, length of stay, and hospital mortality and discharge status.
They found that overall patient age distribution was remarkably similar between the two countries, although the U.S. had proportionally more admissions over the age of 85 (7.8 percent versus 3.2 percent.)
However, the degree of illness of the patients prior to admission was strikingly different. Patients admitted to the ICU in the U.K. were sicker patients who had been in the hospital longer. Also, many more of the patients admitted in the U.K. were mechanically ventilated.
In contrast, U.S. patients were more likely to be admitted to the ICU straight from the emergency room compared to U.K. patients, indicating that fewer ICU beds in the U.K. may necessitate patients spending more time in the general wards than in the U.S.
Dr. Wunsch and colleagues found that hospital mortality for ICU patients was substantially higher in the U.K. than in the U.S., even after accounting for severity of illness, probably because of "a combination of many unmeasured differences in both patients and healthcare systems," said Dr. Wunsch. However, when Dr. Wunsch and colleagues compared subgroups of similarly ill patients—those who were admitted directly from the emergency room and who had been mechanically ventilated in the first 24 hours after admission—the mortality rates were similar.
"These findings highlight the importance of comparing 'like with like', and how hard that can be when looking at heterogeneous patients cared for in different healthcare systems," said Dr. Wunsch.
Comparing hospital mortality between the countries was also confounded by the trend for U.S. ICUs to discharge patients to "skilled care facilities" rather than directly home, as was the case in the U.K.
"The U.S. and the U.K. have very different discharge patterns, and the trend in the U.S. has been to shorten hospital length of stay and discharge people earlier to other types of facilities." said Dr. Wunsch. "If you look at hospital length-of-stay information it looks like [the U.S. is] very efficient, but many of these patients are actually going to a skilled care facility where the mortality is a lot higher than among those who go home. The effect is that for studies of ICU patients, there is a fair amount of mortality that occurs after intensive care that is outside of the hospital. This practice makes it hard to compare U.S. hospital mortality to other countries that tend to keep people in the hospital until they either die or are able to go home."
In spite of the difficulties in making direct comparisons between the countries, the study provides valuable information regarding the impact of ICU resources on admission practices and demonstrates some large differences in healthcare delivery. "The differences in the types of patients admitted to the ICU, and the patterns of hospital care for these critically ill patients really are enormous," said Dr. Wunsch.
In future research, Dr. Wunsch and colleagues hope to make more direct comparisons between groups of similar patients. "We want to understand the key differences between these two different models of ICU access," said Dr. Wunsch. "On the one hand, we want to ask at what point does restricted access to care translate into poorer patient outcomes? On the other, at what point are we no longer delivering intensive care that is helpful to patients?"
### END
Difference in ICU care between the US and UK reflect extremes of bed availability
2011-04-14
ELSE PRESS RELEASES FROM THIS DATE:
Increased prevention efforts may not reduce spread of hospital-based bacteria
2011-04-14
WHAT:
Expanded use of active surveillance for bacteria and of barrier precautions—specifically, gloves and gowns—did not reduce the transmission of two important antibiotic-resistant bacteria in hospital-based settings, according to a prospective, randomized clinical trial conducted in 18 intensive care units in the United States. Incomplete compliance by health
care providers with recommended hand hygiene procedures and the use of gloves and gowns, along with time lags in confirming the presence of bacteria in patients, may have
contributed to the findings, which ...
Experimental Alzheimer's disease drugs might help patients with nerve injuries
2011-04-14
Drugs already in development to treat Alzheimer's disease may eventually be tapped for a different purpose altogether: re-growing the ends of injured nerves to relieve pain and paralysis. According to a new Johns Hopkins study, experimental compounds originally designed to combat a protein that builds up in Alzheimer's-addled brains appear to make crushed or cut nerve endings grow back significantly faster, a potential boon for those who suffer from neuropathies or traumatic injuries.
The new drugs target a protein known as "-Site amyloid precursor protein cleaving ...
Stanford research casts sober light on Russia's mortality crisis
2011-04-14
With the collapse of the Soviet Union, Russians were faced with more than the demise of a political system. Working-age men began dying in droves, and the country saw a 40 percent surge in deaths between 1990 and 1994.
The killer was often alcohol – that much was clear. And for years, many economists and political scientists have blamed Russia's lurch toward democracy and capitalism for driving those men to drink. They reasoned that privatization left many people unskilled and unemployable, ushering in a sense of listlessness and depression that mixed too easily with ...
Berkeley Lab scientists find that normal breast cells help kill cancer cells
2011-04-14
It is well known that the human body has a highly developed immune system to detect and destroy invading pathogens and tumor cells. Now, researchers at the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have shown that the body has a second line of defense against cancer – healthy cells. A new study shows that normal mammary epithelial cells, as they are developing, secrete interleukin 25, a protein known for its role in the immune system's response to inflammation, for the express purpose of killing nearby breast cancer cells.
"We found ...
The TET1 enzyme steers us through fetal development and fights cancer
2011-04-14
To ensure normal fetal development and prevent disease, it is crucial that certain genes are on or off in the right time intervals. Researchers in Professor Kristian Helin's group at BRIC, University of Copenhagen, have now shown how the TET1 enzyme controls the activity of our genes. The results are just published in the journal Nature.
Control of our genes
The complete human genetic code was mapped in 2000. However, it has become clear that the genetic code itself only in part can answer how an individual develops and is protected against disease. What is detrimental ...
Toygaroo.com Provides Toy Rental Service for Hospitality Industry
2011-04-14
Toygaroo.com, a pioneering online toy rental company, has announced that its services are now available for organizations in the hospitality industry.
The company's unique service, which operates similar to Netflix, can now be easily integrated into existing hotel guest offerings, allowing them to provide toys available for families upon check-in. Once the guests have completed their stay and returned the toys, the hotel can then send the toys back to Toygaroo.
"By working with us, hotels and resorts can improve their guest retention by offering activities for kids ...
Biochemist uses computer models to study protein involved with cancer, aging and chronic disease
2011-04-14
MANHATTAN, Kan. -- A new biophysical and biochemical study may lead to better understanding of how structural flexibility controls the interaction of a protein that is closely involved with cancer, aging and other chronic diseases -- thereby facilitating future development of better therapeutic strategies, according to a Kansas State University biochemist.
Jianhan Chen, an assistant professor of biochemistry, was one of the researchers on a collaborative project that took a combined computational and experimental approach to understand how protein p21 functions as a versatile ...
How extraneous factors impact judicial decision-making
2011-04-14
BOSTON/NEW YORK – April 12, 2011 –A study by Columbia Business School Professor Jonathan Levav, Class of 1967 Associate Professor of Business, Marketing and Professor Shai Danziger, Chairperson, Department of Management, Guilford Glazer Faculty of Business and Management, Ben-Gurion University of the Negev and Liora Avnaim-Pesso , a graduate student of Ben-Gurion University of the Negev, recently featured online in the Proceedings of the National Academy of Sciences (PNAS), finds that a judge's willingness to grant parole can be influenced by the time between their latest ...
Should My Wedding Photographer Use Digital or Traditional Film?
2011-04-14
Among the many questions you need to ask prospective wedding photographers is whether they shoot weddings digitally or with traditional film. There are pros and cons for each type of photographic medium.
Denver wedding photography expert Matt Kelly of Ambisuite Weddings said, "When choosing between digital and film, ask yourself what you want your wedding photographs to capture. Then look at the digital and film photography each photographer has taken. You should be able to make your decision then."
Wedding Photographs: digital vs. film resolution
Certainly you ...
Are your values right or left? The answer is more literal than you think
2011-04-14
Up equals good, happy, optimistic; down the opposite. Right is honest and trustworthy. Left, not so much. That's what language and culture tell us. "We use mental metaphors to structure our thinking about abstract things," says psychologist Daniel Casasanto, "One of those metaphors is space."
But we don't all think right is right, Casasanto has found. Rather, "people associate goodness with the side they can act more fluently on." Right-handed people prefer the product, job applicant, or extraterrestrial positioned to their right. Lefties march to a left-handed drummer. ...