Changes in cardiovascular risk factors and health care expenditures among patients prescribed semaglutide

JAMA Network Open

2025-08-08

(Press-News.org) About The Study: In this cohort study of adults prescribed semaglutide, initiation was associated with reductions in weight and cardiovascular risk factors but increases in health care expenditures, excluding semaglutide costs. These findings suggest potential clinical benefits in routine practice, while highlighting the need to evaluate the long-term impact of semaglutide on economic outcomes.

Corresponding Authors: To contact the corresponding authors, email Jason Abaluck, PhD, (jason.abaluck@yale.edu) and Yuan Lu, ScD, (y.lu@yale.edu).

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2025.26013)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.26013?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=080825

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

END

ELSE PRESS RELEASES FROM THIS DATE:

Prescription drug utilization and spending by race, ethnicity, payer, health condition, and US state

2025-08-08

About The Study: In this cross-sectional study of 143 health conditions among persons in 50 states and Washington, DC, per capita pharmaceutical use was highest among white populations and lowest among Asian or Pacific Islander and Hispanic populations. However, after standardizing for age and disease prevalence (for 52 conditions with available data), prescription fills were substantially lower for Black populations relative to the all-population mean. These patterns varied by state, highlighting the need for local- and condition-specific ...

Mobile phone app reduced suicidal behavior among high-risk patients

2025-08-08

COLUMBUS, Ohio – A mobile phone app designed to deliver suicide-specific therapy reduced suicidal behavior among high-risk psychiatric inpatients, according to a new study by scientists at Yale School of Medicine and The Ohio State University Wexner Medical Center and College of Medicine. The study, published Aug. 8, 2025 in JAMA Network Open, found that the app, OTX-202, reduced the recurrence of post-discharge suicide attempts by 58.3% among patients who had previously attempted suicide. This reduction is a critical achievement for a group that is particularly vulnerable to repeated suicidal behaviors, the researchers said. Users of the app also experienced ...

SNU researchers develop wearable blood pressure monitor that attaches like a bandage for real-time continuous measurement

2025-08-08

Seoul National University College of Engineering announced that a research team led by Professor Seung Hwan Ko of the Wearable Soft Electronics Lab, Department of Mechanical Engineering, has developed a wearable electronic device that attaches to the skin like a bandage and enables real-time, continuous monitoring of blood pressure over extended periods. Unlike conventional cuff-based blood pressure monitors that use an inflatable air bladder to apply pressure to the arm, this new technology continuously measures blood pressure with a compact, flexible electronic patch, garnering ...

How a rare cycad's wax crystals conjure blue without pigment

2025-08-08

The endangered South African cycad Encephalartos horridus may resemble a relic from the Jurassic age, but the species itself evolved long after dinosaurs disappeared. Still, it carries a biochemical legacy inherited from its distant ancestors—plants that once thrived alongside Jurassic fauna. A team led by Hiroshima University (HU) researchers found that its spiky, silvery-blue leaves owe their color not to pigment, but to a wax-based optical effect produced by a lipid compound that may date back to the dawn of land plants. In ...

Dana-Farber Cancer Institute unveils groundbreaking blood test for multiple myeloma

2025-08-08

Boston, MA — Researchers at Dana-Farber Cancer Institute have developed a blood test that could transform the diagnosis and monitoring of multiple myeloma (MM) and its precursor conditions. The new method, known as SWIFT-seq, utilizes single-cell sequencing to profile circulating tumor cells (CTCs) in the blood, offering a non-invasive alternative to traditional bone marrow biopsies. The study was published in Nature Cancer. “A lot of work has gone into the identification of genomic and transcriptomic features that predict worse outcome in MM, but we are still lacking the tests to measure them in our patients, said ...

Public data reveal extent of air quality impacts during 2025 Los Angeles wildfires

2025-08-08

In early 2025, wildfires spread in Los Angeles, destroying tens of thousands of homes and businesses. During the fires, smoke blanketed the region and online maps provided residents with rapid air quality information. Now, a study in ACS’ Environmental Science & Technology Letters compares the data that went into the maps from federal monitoring stations, low-cost sensors and satellites. Their results highlight the importance of combining multiple data sources to form easily accessible information for the public. “Timely and accurate air quality information is crucial for the public to ...

Towards better earthquake risk assessment with machine learning

2025-08-08

“A building is only as strong as its foundation” is a common adage to signify the importance of having a stable and solid base to build upon. The type and design of foundation are important for ensuring the structural safety of a building. Among several factors that can affect the design and laying of a foundation, bearing stratum depth, namely the depth at which the underlying layer of soil or rock has adequate strength to support a foundation, is one of the most crucial. This is because in regions that are prone to earthquakes or landslides, the bearing stratum depth, also ...

Reducing the global burden of liver cancer: Recommendations from The Lancet commission

2025-08-08

Liver cancer is the sixth most common cancer as well as the third highest cause of cancer-related mortality worldwide. In particular, a subtype of liver cancer known as hepatocellular carcinoma accounts for around 80% of all liver cancer cases. Given the increasing disease burden of hepatocellular carcinoma globally, a Commission consisting of experts in a wide range of fields – from clinical medicine to public health – has now been established to tackle this issue. Recently, in a comprehensive ...

Researchers succeed in building a low temperature hydrogen fuel cell, thanks to a scandium superhighway

2025-08-08

Fukuoka, Japan—As global energy demand increases, researchers, industries, governments, and stakeholders are working together to develop new ways of meeting that demand. This is especially important as we address the ongoing climate crisis and transition away from fossil fuels. One very promising type of energy generation is solid-oxide fuel cells, or SOFCs. Unlike batteries, which release stored chemical energy as electricity, fuel cells convert chemical fuel directly into electricity and continue to do so as long as fuel is provided. A common ...

New UC Irvine survey reveals shifting work landscape

2025-08-08

The University of California, Irvine School of Social Ecology today released the results of its latest UCI-OC Poll, shedding light on the changing nature of work in Orange County two years after the official end of the COVID-19 pandemic. Conducted from June 20 to July 1, 2025, the survey of 800 Orange County adults offers insights into remote work preferences, attitudes toward artificial intelligence and overall job satisfaction – providing valuable insights for business leaders and policymakers navigating ...

Changes in cardiovascular risk factors and health care expenditures among patients prescribed semaglutide

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: