PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Early prostate cancer detection, screening: No benefit for men with low baseline PSA value

2010-09-13
(Press-News.org) Men aged 55 to 74 years who have low baseline blood levels of prostate specific antigen (PSA) are not likely to benefit from further screening and treatment. That is the conclusion of a new study published early online in Cancer, a peer-reviewed journal of the American Cancer Society. The aim of the study is to help physicians and patients weigh the pros and cons of prostate cancer screening and early detection.

Prostate cancer is the most commonly diagnosed malignancy and the third leading cause of death from cancer in men in Western countries. While a man in the United State has about a one in six chance of being diagnosed with prostate cancer during his lifetime, his risk of dying from the disease is relatively low (about one in 36).

Pim van Leeuwen, MD, of the Erasmus University Medical Centre in Rotterdam, the Netherlands, led a team that tried to identify if the baseline PSA can predict which men have most benefit from additional screening. The investigators compared the incidence of prostate cancer with deaths from prostate cancer as related to PSA levels in 43,987 men aged 55 to 74 years who were enrolled between 1993 and 1999 in the European Randomized Study of Screening for Prostate Cancer (ERSPC) study in the Netherlands, Sweden, and Finland. An additional 42,503 men in the same age range from Northern Ireland who had their PSA levels measured between 1994 and 1999 were also included. All men had PSA levels that were under 20 ng/ml at the start of the study, and were followed for prostate cancer incidence and causes of death through 2006.

A total of 5,861 prostate cancer cases arose during the study period, and prostate cancer death rates were highest in men with high PSA levels at the start of the study. The researchers found that for men with PSA levels between zero and 1.9 ng/ml, a total of 24,642 men would need to be screened and 724 cases of prostate cancer would need to be treated to prevent just one death from prostate cancer. For men with PSA levels between 10 and 19.9 ng/ml, the benefits of screening and treatment were more favorable: a total of 133 men would need to be screened to prevent one death from prostate cancer.

This study indicates that a man's PSA level before diagnosis is a strong predictor for his risk of dying from prostate cancer. For men aged 55 to 74 years who have low PSA levels, the benefits of aggressive follow-up testing and treatment seem limited. Without providing benefits, they may increase prostate cancer diagnoses and lead to overtreatment and increased costs.

"The greatest benefits of early detection programs may be when men, aged 55-74 years, are diagnosed and treated when their serum PSA is in the range 4.0-9.9 ng/ml or 10.0-19.9 ng/ml. Furthermore, following research efforts that recommend more intensive PSA based screening by lowering the PSA cut-off may greatly increase the number of men that need additional investigations and treatment, whilst having little effect on the reduction of prostate cancer mortality," the authors wrote.

Dr. van Leeuwen cautioned that,"the results presented in the current study are limited due to the relatively short follow-up. Consequently the pros of early detection and screening may increase with longer the follow-up while the cons may relatively decrease."

INFORMATION:

END



ELSE PRESS RELEASES FROM THIS DATE:

National study finds 70 percent increase in basketball-related traumatic brain injuries

2010-09-13
A new study conducted by researchers at the Center for Injury Research and Policy at Nationwide Children's Hospital examined basketball-related injuries treated in emergency departments among children and adolescents between the ages of 5 and 19 from 1997 to 2007. According to the study, more than 4 million basketball-related injuries were treated in emergency departments during the 11-year study. While the number of injuries decreased 22 percent over the course of the study, the average number of injuries per year (375,350) remained high. Data from the study, being ...

MiniFrame and VeryPC Join Forces to Offer the Greenest IT Solution

2010-09-13
Two multi-award winning green IT companies, VeryPC and MiniFrame have today announced their collaboration to produce a range of high performance, energy saving solutions to desktop virtualization. The GreenHive for SoftXpand range combines energy efficient software expertise of MiniFrame with the life-cycle engineering and energy calibrating hardware ingenuity of VeryPC. Close collaboration between the two companies allows VeryPC to optimize and produce a dedicated appliance for MiniFrame's award-winning SoftXpand multi-user software. VeryPC GreenHives enhance the SoftXpand ...

Registration Opens for Olney Chamber's 31st Annual Community Night

2010-09-13
The event is scheduled for 5 to 8:30 p.m., Wednesday, Oct. 6 at Longwood Community Center, 19035 Georgia Ave., Brookeville, 1.5 miles north of Route 108. Admission is free. Community Night features a business expo of 100+ displays and the Taste of Olney where the area's premier restaurants present their tasty offerings. Registration can be completed online at http://www.olneymd.org, by mail, by fax or in person at the Chamber's Office and Visitors Center, 3460 Olney-Laytonsville Rd., Olney. "Community Night is an outstanding venue for companies and organizations to ...

SEPTEMBER 30, 2010 ~~ SustainableContentment.com celebrates recovery from Childhood Obesity.

2010-09-13
Listen to an unprecedented panel of special guest experts and authors from a variety of professions: Medical, Health and Fitness; Sociology, Diet and Nutrition; Psychology, Nursing, Wellness Coaching, Holistic Medicine, etc., as they tackle the difficult questions about childhood obesity. To participate: Please RSVP at http://www.sustainablecontentment.com Teleseminar: Thurs, Sep 30, 2010 6PM PST, 8PM CST, 9PM EST to access seminar, call this number on Sep. 30th: 1-712-432-3900 access code: 625350# ALPHABETICAL LISTING OF SPECIAL GUEST EXPERTS: ALVATER, Pat -- ...

Second World Productions Presents for Immediate Release: Brandism on the Go! Program Launched Featuring New York's Highline and Architect Anna Klingmann

2010-09-13
The first of its kind, the show kicks off at New York City's Highline, a development which harnessed the power of architecture to create a recognizable brand and inspire a revitalization of the Meat Packing District. The intro episode features architect Anna Klingmann, architect and author and her insights on what Brandism is and how she started her journey combining architecture and branding in global projects around the world. Next episodes are slated to highlight iconic brand destinations throughout New York City. Anna Klingmann's book "Brandscapes: Architecture ...

ChristmasKNIGHTS.com designer hangs customers' personalities out for all to see with custom holiday wreaths!

2010-09-13
It doesn't matter if you're into Barbie dolls, music, sports, or sex and Rock 'N Roll, Patsy Knights-Brown can show customers how to take a few personal items that reflect their personality and customize a holiday wreath that will make their door the envy of the neighborhood. A bag full of old mismatched sparkling jewelry, a broken rhinestone belt buckle & buttons, and a few feathers are transformed into a "Diva Wreath" with lots of sparkle and bling-bling. There's even a spring-time wreath complete with tea cup and saucer, and her 2010 signature luxury wreath, 'The Patsy' ...

Martin Brossman Linkedin Expert Chosen as Thought Leader at Second Annual Real Estate BarCamp RDU

2010-09-13
Real Estate BarCampRDU was a one day event focused on Real Estate and topics the 300 in attendance were interested in exploring. Throughout the day, sessions on a variety of social media and technology subjects, lead by experts, "thought leaders" gave a short talk on a subject to get the conversation going, then opened the room to question and answer. The day long event was held at the Raleigh Regional Association of Realtors, 111 Realtors Way, Cary, NC 27513 Session Thought Leader Martin Brossman, the Triangle LinkedIn expert and trainer who consults for several real ...

Guidance Software, the Leading Company in Digital Investigations in Aisa

2010-09-13
Around the globe, Guidance Software is recognized as the leading company in eDiscovery and digital investigations. Their world-class solutions for each intensive computer investigation need is now distributed across Asia through Manifest Marketing. Ensuring security is one of the primary investments that any private or non-private company does within their premises. One of the hardest areas for this aim is the digital aspect, where highly intelligent programs and equipment is utilized in order to ensure optimal security. Fortunately, Guidance Software is very helpful ...

Gifted Gospel Jazz Group, 3 Central, Takes Local Ministry Nationwide With "A Feelin' Inside"

2010-09-13
Gospel Jazz is a genre that's busting out at the seams. Artists are expressing their spirituality in jazzy tones and gaining legions of fans along the way. 3 Central, consisting of Ken Anderson, Everett Moore and Russell Moore, are three men on a mission to spread the love of Christ through powerful instrumental and inspirational music. Hailing from St. Louis, MO, the group has been one of the most sought-after Gospel Jazz groups in the region earning the Best Contemporary Jazz Artist Award in St. Louis Award (2002). They've opened for such artists as Gerald Albright, Kem, ...

Olympian University and Aladdin Beauty College Offer Buy One Get One Free for Your BFF

2010-09-13
Best Friends Forever (BFF) can share quality time and save money at the BFF Buy One Get One Free Special Sept. 13-24 at the Olympian University cosmetology schools at: 1011 E 10th Street in Alamogordo; 6300 San Mateo Blvd NE in Albuquerque; 1460 Missouri Ave in Las Cruces and Aladdin Beauty College, 108 S. Union in Roswell. When one person comes in and gets either a haircut, wax services, manicure or purchases any Peter Hantz products during the BFF special, the client's BFF will receive the same service or product for free. "Everyone has someone in their lives that ...

LAST 30 PRESS RELEASES:

Making an impact. Research studies a new side of helmet safety: faceguard failures

Specific long term condition combinations have major role in NHS ‘winter pressures’

Men often struggle with transition to fatherhood amid lack of targeted information and support

More green space linked to fewer preventable deaths in most deprived areas of UK

Immunotherapy drug pembrolizumab improves outcomes for patients with soft tissue sarcoma

A formula for life? New model calculates chances of intelligent beings in our Universe and beyond

Could a genetic flaw be the key to stopping people craving sugary treats?

Experts urge complex systems approach to assess A.I. risks

Fossil fuel CO2 emissions increase again in 2024

Winners of Applied Microbiology International Horizon Awards 2024 announced

A toolkit for unraveling the links between intimate partner violence, trauma and substance misuse

Can everyday physical activity improve cognitive health in middle age?

Updated guidance reaffirms CPR with breaths essential for cardiac arrest following drowning

Study reveals medical boards rarely discipline physician misinformation

New treatment helps children with rare spinal condition regain ability to walk

'Grow Your Own' teacher prep pipeline at the University of Louisiana at Lafayette funded by US Department of Education

Lab-grown human immune system uncovers weakened response in cancer patients

More than 5 million Americans would be eligible for psychedelic therapy, study finds

Children’s Hospital of Philadelphia researchers find community health workers play critical role in coordinating asthma care across home, school and community

Comprehensive Genomic Profiling leads to better patient outcomes, new joint study says  

Animated movie characters with strabismus are more likely to be villains, study finds

How retailers change ordering strategy when a supplier starts its own direct channel

Young coral use metabolic tricks to resist bleaching

Protecting tax whistleblowers pays off

Bioluminescent proteins made from scratch enable non-invasive, multi-functional biological imaging

New study links air pollution with higher rates of head and neck cancer

LSU researchers excavate earliest ancient Maya salt works

Building a diverse wildland fire workforce to meet future challenges

MBARI researchers discover remarkable new swimming sea slug in the deep sea

Decentralized social media ‘increases citizen empowerment’, says Oxford study

[Press-News.org] Early prostate cancer detection, screening: No benefit for men with low baseline PSA value