PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Einstein offers easy-to-use genome analyzer to scientific community

2011-06-08
(Press-News.org) June 6, 2011 – (BRONX, NY) – Scientists at Albert Einstein College of Medicine of Yeshiva University have developed a desktop genome analyzer and browser that allows biologists to rapidly and easily analyze and process their high-throughput data. The open-source software, called GenPlay, is described in the May 19 online edition of Bioinformatics.

Currently, genomic data is analyzed mainly by information specialists rather than by the biologists who designed the experiments that produce the data. GenPlay was created with the goal of offering biologists a user-friendly, multi-purpose tool that can help them visualize, analyze and transform their raw data into biologically relevant tracks.

"The first human genome was sequenced 10 years ago by an international consortium at a cost of $7 billion," notes GenPlay co-developer Eric Bouhassira, Ph.D., senior author of the Bioinformatics article, professor of medicine and of cell biology, and the Ingeborg and Ira Leon Rennert Professor of Stem Cell Biology and Regenerative Medicine at Einstein. "But today, a complete genome can be sequenced for less than $10,000 and the cost is predicted to drop to less than $1,000 in a few years. The dramatic dip in cost has led to the creation of an avalanche of new data that biologists are having trouble analyzing. GenPlay is intended to make it easier for biologists to make sense of their data."

A dozen or so genome browsers are currently available. GenPlay offers a major advantage over the others, says Dr. Bouhassira, because it "emphasizes letting biologists take control of their own data by providing continuous visual feedback together with extremely rapid browsing at every decision point during an analysis."

GenPlay handles three major types of data: data from gene expression studies, epigenetic data, and single nucleotide polymorphism (SNP) data. The free GenPlay software is available from http://www.genplay.net (http://genplay.einstein.yu.edu/wiki/index.php/Main_Page).

### The Bioinformatics paper is titled "GenPlay, a Multi-Purpose Genome Analyzer and Browser." The lead author of the paper is Julien Lajugie, M.S., associate in Einstein's department of medicine, who co-developed GenPlay and wrote the GenPlay program. The project was funded by New York State Stem Cell Science (NYSTEM)( http://stemcell.ny.gov/).

About Albert Einstein College of Medicine of Yeshiva University

Albert Einstein College of Medicine of Yeshiva University is one of the nation's premier centers for research, medical education and clinical investigation. During the 2009-2010 academic year, Einstein is home to 722 M.D. students, 243 Ph.D. students, 128 students in the combined M.D./Ph.D. program, and approximately 350 postdoctoral research fellows. The College of Medicine has 2,775 fulltime faculty members located on the main campus and at its clinical affiliates. In 2009, Einstein received more than $155 million in support from the NIH. This includes the funding of major research centers at Einstein in diabetes, cancer, liver disease, and AIDS. Other areas where the College of Medicine is concentrating its efforts include developmental brain research, neuroscience, cardiac disease, and initiatives to reduce and eliminate ethnic and racial health disparities. Through its extensive affiliation network involving five medical centers in the Bronx, Manhattan and Long Island - which includes Montefiore Medical Center, The University Hospital and Academic Medical Center for Einstein - the College of Medicine runs one of the largest post-graduate medical training programs in the United States, offering approximately 150 residency programs to more than 2,500 physicians in training. For more information, please visit www.einstein.yu.edu



ELSE PRESS RELEASES FROM THIS DATE:

GPS stations can detect clandestine nuclear tests

2011-06-08
VIENNNA, Austria – At the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO) meeting this week, American researchers are unveiling a new tool for detecting illegal nuclear explosions: the Earth's global positioning system (GPS). Even underground nuclear tests leave their mark on the part of the upper atmosphere known as the ionosphere, the researchers discovered, when they examined GPS data recorded the same day as a North Korean nuclear test in 2009. Within minutes on that day, GPS stations in nearby countries registered a change in ionospheric electron density, ...

Super-mini vehicles carry therapeutics and imaging agents into body with mega results

2011-06-08
Measured in billionths of a meter, self-assembling nano-sized devices designed to carry drugs and imaging agents into the body are revolutionizing medicine by improving drug solubility and bio-distribution, providing a platform for combining targeting and imaging agents, and enabling membrane barriers to be crossed as well as making drug and imaging agent combination therapies possible. Self-assembling nano devices are now enlisted in the nanomedicine revolution, a story as told by researchers from Duke University and the University of Southern California in an article ...

ExpertPages.com - The Premier Expert Witness Site - Announces the Release of ExpertFinder, its Free iPhone/iPad App

2011-06-08
ExpertPages.com, the first and leading online directory for expert witnesses and consultants in litigation and forensic matters, today announced the release of its much anticipated iPhone and iPad ExpertFinder App. ExpertFinder enables attorneys and legal professionals to effortlessly and effectively identify and contact highly qualified experts from the palm of their hand. The ExpertFinder App is available to lawyers and legal professionals for free in the App Store. The no cost download can be accessed on iTunes at http://expertpages.com/press/expertfinder.htm. ...

Drug shows promise in prostate cancer spread to bone

Drug shows promise in prostate cancer spread to bone
2011-06-08
ANN ARBOR, Mich. — A new drug to treat prostate cancer shows early promise, particularly against tumors that have spread to the bone, a multi-site study shows. The drug Cabozantinib is designed to target mainly two important pathways linked to the growth and spread of prostate cancer. The drug had the most effect on tumors that had spread to the bone. "Not only did three-quarters of bone scans have partial or complete resolution, but this was accompanied by improvement in bone pain and decreased need for narcotic use," says lead study author Maha Hussain, M.D., FACP, ...

Randy Heinitz Introduces Market Snapshot for the Palm Springs Real Estate Market Utilizing Real Time MLS Data; Get Your Property's Current Value Quickly Online

Randy Heinitz Introduces Market Snapshot for the Palm Springs Real Estate Market Utilizing Real Time MLS Data; Get Your Propertys Current Value Quickly Online
2011-06-08
Selling PS: It's So Sunny!, one of the Palm Springs area's most creative real estate marketing brands, has added Market Snapshot to their already user friendly website. In an ongoing effort to enhance the consumer's experience on the website (http://www.SellingPS.com), Market Snapshot provides valuable and timely data, allowing consumers to simply click on the icon and instantly compare home prices in their neighborhood and get community and school information as well. Market Snapshot provides up-to-the minute MLS graphical reports - automatically delivered and ...

Air quality worsened by paved surfaces

Air quality worsened by paved surfaces
2011-06-08
New research focusing on the Houston area suggests that widespread urban development alters weather patterns in a way that can make it easier for pollutants to accumulate during warm summer weather instead of being blown out to sea. The international study, led by the National Center for Atmospheric Research (NCAR), could have implications for the air quality of fast-growing coastal cities in the United States and other mid-latitude regions overseas. The reason: the proliferation of strip malls, subdivisions and other paved areas may interfere with breezes needed to ...

NASA sees a hot tower in first tropical depression of the eastern Pacific

NASA sees a hot tower in first tropical depression of the eastern Pacific
2011-06-08
The Tropical Rainfall Measuring Mission satellite called TRMM has the ability to see rainfall rates and heights of thunderstorm clouds within a tropical cyclone, and data from the satellite confirmed a "hot tower" near the center of the first tropical depression of the eastern Pacific Hurricane Season. Tropical Depression 1E formed when the low pressure area called System 91E strengthened overnight. Today, June 7, Tropical Depression 1E (TD1E) was located about 365 miles (590 km) south of Acapulco, Mexico near 11.6 North and 100.0 West. It had maximum sustained winds ...

'Wrong'-time eating reduces fertility in fruit flies

2011-06-08
PHILADELPHIA - Dieticians will tell you it isn't healthy to eat late at night: it's a recipe for weight gain. In fruit flies, at least, there's another consequence: reduced fertility. That's the conclusion of a new study this week in Cell Metabolism by researchers at the Perelman School of Medicine at the University of Pennsylvania, in which they manipulated circadian rhythms in fruit flies and measured the affect on egg-laying capacity. Lead author Amita Sehgal, PhD, John Herr Musser Professor of Neuroscience, stresses, though, that what is true in flies grown in ...

Universal flu vaccine clinical trials show promise

2011-06-08
GALVESTON, Texas — A universal influenza vaccine targeting a protein common to all strains of influenza A has safely produced an immune response in humans. If proven effective, the vaccine could eliminate the practice of creating a new flu vaccine annually to match predicted strains, with major implications for global health. The results of the clinical trials, led by the University of Texas Medical Branch at Galveston in collaboration with biotechnology company VaxInnate and funded by $9.5 million grant from the Bill and Melinda Gates Foundation, were published today ...

NASA's solar dynamics observatory catches 'surfer' waves on the sun

NASAs solar dynamics observatory catches surfer waves on the sun
2011-06-08
Cue the surfing music. Scientists have spotted the iconic surfer's wave rolling through the atmosphere of the sun. This makes for more than just a nice photo-op: the waves hold clues as to how energy moves through that atmosphere, known as the corona. Since scientists know how these kinds of waves -- initiated by a Kelvin-Helmholtz instability if you're being technical -- disperse energy in the water, they can use this information to better understand the corona. This in turn, may help solve an enduring mystery of why the corona is thousands of times hotter than originally ...

LAST 30 PRESS RELEASES:

1 in 8 Italian cetacean strandings show evidence of fishery interactions, with bottlenose and striped dolphins most commonly affected, according to analysis across four decades of data and more than 5

In the wild, chimpanzees likely ingest the equivalent of several alcoholic drinks every day

Warming of 2°C intensifies Arctic carbon sink but weakens Alpine sink, study finds

Bronze and Iron Age cultures in the Middle East were committed to wine production

Indian adolescents are mostly starting their periods at an earlier age than 25 years ago

Temporary medical centers in Gaza known as "Medical Points" (MPs) treat an average of 117 people daily with only about 7 staff per MP

Rates of alcohol-induced deaths among the general population nearly doubled from 1999 to 2024

PLOS One study: In adolescent lab animals exposed to cocaine, High-Intensity Interval Training boosts aversion to the drug

Scientists identify four ways our bodies respond to COVID-19 vaccines

Stronger together: A new fusion protein boosts cancer immunotherapy

Hidden brain waves as triggers for post-seizure wandering

Music training can help the brain focus

Researcher develop the first hydride ion prototype battery

MIT researchers find a more precise way to edit the genome

‘Teen’ pachycephalosaur butts into fossil record

Study finds cocoa extract supplement reduced key marker of inflammation and aging

Obesity treatment with bariatric surgery vs GLP-1 receptor agonists

Nicotinamide for skin cancer chemoprevention

Novel way to ‘rev up’ brown fat burns calories, limits obesity in mice

USC Stem Cell-led team makes major advance toward building a synthetic kidney

Delegation to Artificial Intelligence can increase dishonest behavior

Repeated head impacts cause early neuron loss and inflammation in young athletes

BU study of young athletes finds neurodegeneration might begin before CTEa

Dr. Carl Nathan wins David and Beatrix Hamburg Award

New microscope captures large, high-resolution images of curved samples in single snapshot

SwRI, UT San Antonio will test technology designed to support extended space missions to Moon, Mars

Hot flashes can be reliably predicted by an ai-driven algorithm developed by UMass Amherst and Embr Labs

FAU/Baptist Health AI spine model could transform lower back pain treatment

CDI Lab, HMH specialists identify vital pathway initiating cellular immunity in Science Immunology journal

University of Pennsylvania professor to receive the 2025 Clinical Research Prize

[Press-News.org] Einstein offers easy-to-use genome analyzer to scientific community