PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

New HIV incidence assays could transform AIDS prevention efforts

2011-06-15
(Press-News.org) HIV prevention activities aiming to reduce incidence could be targeted more effectively and efficiently if a quick, easy, valid, and precise method of estimating incidence in populations were available. These are the conclusions of a group of international experts convened to discuss the challenges and progress in the field, with the aim of stimulating new investment in technologies for identifying recent HIV infections.

To tackle the challenges—which include technical and market-related issues—and move towards the goal of having a thoroughly validated incidence assay, the expert Incidence Assay Critical Path Working Group (funded in part by the Bill & Melinda Gates Foundation) charted the activities, milestones, and decisions that will be required in the coming years.

INFORMATION:

Funding: The article draws on some material originally written as a background reading document for a meeting sponsored by the Bill & Melinda Gates Foundation and the National Institutes of Health that was completed under a contract between Imperial College London and the Bill & Melinda Gates Foundation. Funding agency staff contributed comments to an early draft of the manuscript. However, the decision to publish was taken by the corresponding author.

Competing Interests: The authors have declared that no competing interests exist. The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the US Centers for Disease Control and Prevention (CDC), The Bill & Melinda Gates Foundation, or the National Institutes of Health.

Citation: Incidence Assay Critical Path Working Group (2011) More and Better Information to Tackle HIV Epidemics: Towards Improved HIV Incidence Assays. PLoS Med 8(6): e1001045. doi:10.1371/journal.pmed.1001045

IN YOUR COVERAGE PLEASE USE THIS URL TO PROVIDE ACCESS TO THE FREELY AVAILABLE PAPER:

http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001045

CONTACT: Dr. Timothy Hallett
Infectious Disease Epidemiology
Imperial College London
Norfolk Place
London W2 1PG
United Kingdom
+44(0)2075941150
timothy.hallett@imperial.ac.uk

END



ELSE PRESS RELEASES FROM THIS DATE:

Migration interception practices are a major threat to health

2011-06-15
In the fifth article of a six-part PLoS Medicine series on migration & health, Zachary Steel from the University of New South Wales in Sydney, Australia and colleagues discuss the health risks associated with "interception strategies" that are used by governments to control and order international migration, especially in terms of halting the movement of irregular migrants, including asylum seekers. Some strategies like immigration detention, the authors argue, pose a serious threat to health and mental health, while others like visa restrictions have a potentially large ...

Scientists image beginning stages of ovarian cancer growth with time-lapse technique

2011-06-15
PHILADELPHIA — Scientists at Harvard University have created a laboratory model using time-lapse video microscopic technology that allows observation of early stages of ovarian cancer metastasis. "We were able to observe key molecular mechanisms that are necessary for the force-dependent processes associated with metastasis," said Joan Brugge, Ph.D., professor and chair of cell biology at Harvard University. These findings are published in Cancer Discovery, the newest journal of the American Association for Cancer Research. According to Brugge, who served as program ...

Ovarian cancer cells bully their way through tissue

2011-06-15
BOSTON, Mass. (June 14, 2011) — A team led by Joan Brugge, the Louise Foote Pfeiffer Professor of Cell Biology at Harvard Medical School, recently shed light on how ovarian cancer spreads. In a paper published in the July edition of the journal Cancer Discovery, the newest journal of the American Association for Cancer Research, Brugge and colleagues found that ovarian cancer cells act like bullies, using brute force to plow their way through tissue and colonize additional organs. "This is the first time that mechanical force has been implicated in the spread of ovarian ...

New light shed on cell division

2011-06-15
Genes control everything from eye color to disease susceptibility, and inheritance - the passing of the genes from generation to generation after they have been duplicated - depends on centromeres. Located in the little pinched waist of each chromosome, centromeres control the movements that separate sister chromosomes when cells divide ensuring that each daughter cell inherits a complete copy of each chromosome. It has long been known that centromeres are not formed solely from DNA; rather, centromere proteins (CENPs) facilitate the assembly of a centromere on each chromosome. ...

Rating hospital quality means asking the right questions, experts say

2011-06-15
With an increased emphasis on grading hospitals and a push to withhold payments from hospitals who don't meet certain standards, two Johns Hopkins researchers argue that more attention needs to be paid to the quality of the measurement tools used to praise and punish. The science of outcomes reporting is young and lags behind the desire to publically report adverse medical outcomes, write Elliott R. Haut, M.D., an associate professor of surgery at the Johns Hopkins University School of Medicine, and Peter J. Pronovost, M.D., Ph.D., a Johns Hopkins professor of anesthesiology ...

Number of paid malpractice claims similar between inpatient and outpatient settings

2011-06-15
In an examination of trends of malpractice claims, there has been a greater decline in the rate of paid claims for inpatient settings than outpatient settings, and in 2009, the number of malpractice claims for events resulting in paid malpractice claims in outpatient and inpatient settings were similar, according to a study in the June 15 issue of JAMA. Much attention has been given to patient safety, but most initiatives have centered around inpatient care. "For example, in the past 5 years, the number of studies funded by the Agency for Healthcare Research and Quality ...

Extensive TV watching linked with increased risk of Type 2 diabetes, CVD and all-cause death

2011-06-15
In an analysis of data from several studies, watching television for 2-3 hours per day or more was associated with a higher risk of type 2 diabetes, fatal and nonfatal cardiovascular disease and all-cause death, according to a study in the June 15 issue of JAMA. Television (TV) viewing is the most commonly reported daily activity apart from working and sleeping in many populations around the world. In the United States, the average number of daily hours of TV viewing has recently been reported to be 5 hours. "Beyond altering energy expenditure by displacing time spent ...

Poorer outcomes linked with certain hormone for patients with early-stage chronic kidney disease

2011-06-15
Patients in the early stages of chronic kidney disease who had elevated levels of the endocrine hormone fibroblast growth factor 23 (that regulates phosphorus metabolism) had an associated increased risk of end-stage renal disease and death, according to a study in the June 15 issue of JAMA. Circulating levels of fibroblast growth factor 23 (FGF-23) increase progressively as kidney function declines. A high level of FGF-23 is associated with mortality in patients with end-stage renal disease, but little is known about its relationship with adverse outcomes in the larger ...

Prolonged TV viewing linked to increased risk of type 2 diabetes, cardiovascular disease

2011-06-15
Boston, MA – Watching television is the most common daily activity apart from work and sleep in many parts of the world, but it is time for people to change their viewing habits. According to a new study from Harvard School of Public Health (HSPH) researchers, prolonged TV viewing was associated with increased risk of type 2 diabetes, cardiovascular disease, and premature death. The study appears in the June 15, 2011, edition of the Journal of the American Medical Association. "The message is simple. Cutting back on TV watching can significantly reduce risk of type ...

Making quantum cryptography truly secure

Making quantum cryptography truly secure
2011-06-15
(14 June 2011) Singapore and Trondheim, Norway: Quantum key distribution (QKD) is an advanced tool for secure computer-based interactions, providing confidential communication between two remote parties by enabling them to construct a shared secret key during the course of their conversation. QKD is perfectly secure in principle, but researchers have long been aware that loopholes may arise when QKD is put into practice. Now, for the first time, a team of researchers at the Centre for Quantum Technologies (CQT) at the National University of Singapore, the Norwegian University ...

LAST 30 PRESS RELEASES:

Post-LLM era: New horizons for AI with knowledge, collaboration, and co-evolution

“Sloshing” from celestial collisions solves mystery of how galactic clusters stay hot

Children poisoned by the synthetic opioid, fentanyl, has risen in the U.S. – eight years of national data shows

USC researchers observe mice may have a form of first aid

VUMC to develop AI technology for therapeutic antibody discovery

Unlocking the hidden proteome: The role of coding circular RNA in cancer

Advancing lung cancer treatment: Understanding the differences between LUAD and LUSC

Study reveals widening heart disease disparities in the US

The role of ubiquitination in cancer stem cell regulation

New insights into LSD1: a key regulator in disease pathogenesis

Vanderbilt lung transplant establishes new record

Revolutionizing cancer treatment: targeting EZH2 for a new era of precision medicine

Metasurface technology offers a compact way to generate multiphoton entanglement

Effort seeks to increase cancer-gene testing in primary care

Acoustofluidics-based method facilitates intracellular nanoparticle delivery

Sulfur bacteria team up to break down organic substances in the seabed

Stretching spider silk makes it stronger

Earth's orbital rhythms link timing of giant eruptions and climate change

Ammonia build-up kills liver cells but can be prevented using existing drug

New technical guidelines pave the way for widespread adoption of methane-reducing feed additives in dairy and livestock

Eradivir announces Phase 2 human challenge study of EV25 in healthy adults infected with influenza

New study finds that tooth size in Otaria byronia reflects historical shifts in population abundance

nTIDE March 2025 Jobs Report: Employment rate for people with disabilities holds steady at new plateau, despite February dip

Breakthrough cardiac regeneration research offers hope for the treatment of ischemic heart failure

Fluoride in drinking water is associated with impaired childhood cognition

New composite structure boosts polypropylene’s low-temperature toughness

While most Americans strongly support civics education in schools, partisan divide on DEI policies and free speech on college campuses remains

Revolutionizing surface science: Visualization of local dielectric properties of surfaces

LearningEMS: A new framework for electric vehicle energy management

Nearly half of popular tropical plant group related to birds-of-paradise and bananas are threatened with extinction

[Press-News.org] New HIV incidence assays could transform AIDS prevention efforts