PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

New HIV incidence assays could transform AIDS prevention efforts

2011-06-15
(Press-News.org) HIV prevention activities aiming to reduce incidence could be targeted more effectively and efficiently if a quick, easy, valid, and precise method of estimating incidence in populations were available. These are the conclusions of a group of international experts convened to discuss the challenges and progress in the field, with the aim of stimulating new investment in technologies for identifying recent HIV infections.

To tackle the challenges—which include technical and market-related issues—and move towards the goal of having a thoroughly validated incidence assay, the expert Incidence Assay Critical Path Working Group (funded in part by the Bill & Melinda Gates Foundation) charted the activities, milestones, and decisions that will be required in the coming years.

INFORMATION:

Funding: The article draws on some material originally written as a background reading document for a meeting sponsored by the Bill & Melinda Gates Foundation and the National Institutes of Health that was completed under a contract between Imperial College London and the Bill & Melinda Gates Foundation. Funding agency staff contributed comments to an early draft of the manuscript. However, the decision to publish was taken by the corresponding author.

Competing Interests: The authors have declared that no competing interests exist. The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the US Centers for Disease Control and Prevention (CDC), The Bill & Melinda Gates Foundation, or the National Institutes of Health.

Citation: Incidence Assay Critical Path Working Group (2011) More and Better Information to Tackle HIV Epidemics: Towards Improved HIV Incidence Assays. PLoS Med 8(6): e1001045. doi:10.1371/journal.pmed.1001045

IN YOUR COVERAGE PLEASE USE THIS URL TO PROVIDE ACCESS TO THE FREELY AVAILABLE PAPER:

http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001045

CONTACT: Dr. Timothy Hallett
Infectious Disease Epidemiology
Imperial College London
Norfolk Place
London W2 1PG
United Kingdom
+44(0)2075941150
timothy.hallett@imperial.ac.uk

END



ELSE PRESS RELEASES FROM THIS DATE:

Migration interception practices are a major threat to health

2011-06-15
In the fifth article of a six-part PLoS Medicine series on migration & health, Zachary Steel from the University of New South Wales in Sydney, Australia and colleagues discuss the health risks associated with "interception strategies" that are used by governments to control and order international migration, especially in terms of halting the movement of irregular migrants, including asylum seekers. Some strategies like immigration detention, the authors argue, pose a serious threat to health and mental health, while others like visa restrictions have a potentially large ...

Scientists image beginning stages of ovarian cancer growth with time-lapse technique

2011-06-15
PHILADELPHIA — Scientists at Harvard University have created a laboratory model using time-lapse video microscopic technology that allows observation of early stages of ovarian cancer metastasis. "We were able to observe key molecular mechanisms that are necessary for the force-dependent processes associated with metastasis," said Joan Brugge, Ph.D., professor and chair of cell biology at Harvard University. These findings are published in Cancer Discovery, the newest journal of the American Association for Cancer Research. According to Brugge, who served as program ...

Ovarian cancer cells bully their way through tissue

2011-06-15
BOSTON, Mass. (June 14, 2011) — A team led by Joan Brugge, the Louise Foote Pfeiffer Professor of Cell Biology at Harvard Medical School, recently shed light on how ovarian cancer spreads. In a paper published in the July edition of the journal Cancer Discovery, the newest journal of the American Association for Cancer Research, Brugge and colleagues found that ovarian cancer cells act like bullies, using brute force to plow their way through tissue and colonize additional organs. "This is the first time that mechanical force has been implicated in the spread of ovarian ...

New light shed on cell division

2011-06-15
Genes control everything from eye color to disease susceptibility, and inheritance - the passing of the genes from generation to generation after they have been duplicated - depends on centromeres. Located in the little pinched waist of each chromosome, centromeres control the movements that separate sister chromosomes when cells divide ensuring that each daughter cell inherits a complete copy of each chromosome. It has long been known that centromeres are not formed solely from DNA; rather, centromere proteins (CENPs) facilitate the assembly of a centromere on each chromosome. ...

Rating hospital quality means asking the right questions, experts say

2011-06-15
With an increased emphasis on grading hospitals and a push to withhold payments from hospitals who don't meet certain standards, two Johns Hopkins researchers argue that more attention needs to be paid to the quality of the measurement tools used to praise and punish. The science of outcomes reporting is young and lags behind the desire to publically report adverse medical outcomes, write Elliott R. Haut, M.D., an associate professor of surgery at the Johns Hopkins University School of Medicine, and Peter J. Pronovost, M.D., Ph.D., a Johns Hopkins professor of anesthesiology ...

Number of paid malpractice claims similar between inpatient and outpatient settings

2011-06-15
In an examination of trends of malpractice claims, there has been a greater decline in the rate of paid claims for inpatient settings than outpatient settings, and in 2009, the number of malpractice claims for events resulting in paid malpractice claims in outpatient and inpatient settings were similar, according to a study in the June 15 issue of JAMA. Much attention has been given to patient safety, but most initiatives have centered around inpatient care. "For example, in the past 5 years, the number of studies funded by the Agency for Healthcare Research and Quality ...

Extensive TV watching linked with increased risk of Type 2 diabetes, CVD and all-cause death

2011-06-15
In an analysis of data from several studies, watching television for 2-3 hours per day or more was associated with a higher risk of type 2 diabetes, fatal and nonfatal cardiovascular disease and all-cause death, according to a study in the June 15 issue of JAMA. Television (TV) viewing is the most commonly reported daily activity apart from working and sleeping in many populations around the world. In the United States, the average number of daily hours of TV viewing has recently been reported to be 5 hours. "Beyond altering energy expenditure by displacing time spent ...

Poorer outcomes linked with certain hormone for patients with early-stage chronic kidney disease

2011-06-15
Patients in the early stages of chronic kidney disease who had elevated levels of the endocrine hormone fibroblast growth factor 23 (that regulates phosphorus metabolism) had an associated increased risk of end-stage renal disease and death, according to a study in the June 15 issue of JAMA. Circulating levels of fibroblast growth factor 23 (FGF-23) increase progressively as kidney function declines. A high level of FGF-23 is associated with mortality in patients with end-stage renal disease, but little is known about its relationship with adverse outcomes in the larger ...

Prolonged TV viewing linked to increased risk of type 2 diabetes, cardiovascular disease

2011-06-15
Boston, MA – Watching television is the most common daily activity apart from work and sleep in many parts of the world, but it is time for people to change their viewing habits. According to a new study from Harvard School of Public Health (HSPH) researchers, prolonged TV viewing was associated with increased risk of type 2 diabetes, cardiovascular disease, and premature death. The study appears in the June 15, 2011, edition of the Journal of the American Medical Association. "The message is simple. Cutting back on TV watching can significantly reduce risk of type ...

Making quantum cryptography truly secure

Making quantum cryptography truly secure
2011-06-15
(14 June 2011) Singapore and Trondheim, Norway: Quantum key distribution (QKD) is an advanced tool for secure computer-based interactions, providing confidential communication between two remote parties by enabling them to construct a shared secret key during the course of their conversation. QKD is perfectly secure in principle, but researchers have long been aware that loopholes may arise when QKD is put into practice. Now, for the first time, a team of researchers at the Centre for Quantum Technologies (CQT) at the National University of Singapore, the Norwegian University ...

LAST 30 PRESS RELEASES:

Making lighter work of calculating fluid and heat flow

Normalizing blood sugar can halve heart attack risk

Lowering blood sugar cuts heart attack risk in people with prediabetes

Study links genetic variants to risk of blinding eye disease in premature infants

Non-opioid ‘pain sponge’ therapy halts cartilage degeneration and relieves chronic pain

AI can pick up cultural values by mimicking how kids learn

China’s ecological redlines offer fast track to 30 x 30 global conservation goal

Invisible indoor threats: emerging household contaminants and their growing risks to human health

Adding antibody treatment to chemo boosts outcomes for children with rare cancer

Germline pathogenic variants among women without a history of breast cancer

Tanning beds triple melanoma risk, potentially causing broad DNA damage

Unique bond identified as key to viral infection speed

Indoor tanning makes youthful skin much older on a genetic level

Mouse model sheds new light on the causes and potential solutions to human GI problems linked to muscular dystrophy

The Journal of Nuclear Medicine ahead-of-print tip sheet: December 12, 2025

Smarter tools for peering into the microscopic world

Applications open for funding to conduct research in the Kinsey Institute archives

Global measure underestimates the severity of food insecurity

Child survivors of critical illness are missing out on timely follow up care

Risk-based vs annual breast cancer screening / the WISDOM randomized clinical trial

University of Toronto launches Electric Vehicle Innovation Ontario to accelerate advanced EV technologies and build Canada’s innovation advantage

Early relapse predicts poor outcomes in aggressive blood cancer

American College of Lifestyle Medicine applauds two CMS models aligned with lifestyle medicine practice and reimbursement

Clinical trial finds cannabis use not a barrier to quitting nicotine vaping

Supplemental nutrition assistance program policies and food insecurity

Switching immune cells to “night mode” could limit damage after a heart attack, study suggests

URI-based Global RIghts Project report spotlights continued troubling trends in worldwide inhumane treatment

Neutrophils are less aggressive at night, explaining why nighttime heart attacks cause less damage than daytime events

Menopausal hormone therapy may not pose breast cancer risk for women with BRCA mutations

Mobile health tool may improve quality of life for adolescent and young adult breast cancer survivors

[Press-News.org] New HIV incidence assays could transform AIDS prevention efforts