PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Graft size and patient age may be predictor of need for future ACL revisions

2011-07-10
(Press-News.org) SAN DIEGO, CA – A smaller sized hamstring graft in an anterior cruciate ligament (ACL) reconstruction patient less than 20 years old may increase revision rates, according to research presented at the American Orthopaedic Society for Sports Medicine's Annual Meeting in San Diego today.

"Hamstring grafts are commonly used in ACL reconstruction surgeries and vary in size, with the average being 8mm in diameter. Our research illustrated that when a patient was younger than 20 years old and had a graft of less than 8mm, they were more likely to have a future revision surgery," said lead researcher, Robert A. Magnussen of Duke Sports Medicine in Durham, North Carolina.

The researchers studied 256 patients who ranged in age from 11 to 52 years old. Eighteen individuals (7 percent) underwent revision ACL surgery at an average of 12 months after the initial surgery. Only 1.7 percent of the individuals with grafts greater than 8 mm had revisions while 13.6 percent of the patients with grafts 7 mm or less had revisions. One revision was required in the 137 patients age 20 or older but 17 revisions were required in the 119 patients under 20. No statistically significant association was determined between the ratio of graft size to patient weight, height or Body Mass Index (BMI).

"Increased activity levels of younger patients may contribute to the increased revision rates noted in the patients studied," said Magnussen. "However, research into why the smaller grafts failed at higher rates is ongoing. We hope to improve ACL reconstruction outcomes for young athletes and help them get back on the field safely."

### The American Orthopaedic Society for Sports Medicine (AOSSM) is a world leader in sports medicine education, research, communication and fellowship, and includes national and international orthopaedic sports medicine leaders. The Society works closely with many other sports medicine specialists, including athletic trainers, physical therapists, family physicians, and others to improve the identification, prevention, treatment, and rehabilitation of sports injuries. AOSSM is also a founding partner of the STOP Sports Injuries campaign to prevent overuse and traumatic injuries in kids. For more information on AOSSM or the STOP Sports Injuries campaign, visit www.sportsmed.org or www.stopsportsinjuries.org


ELSE PRESS RELEASES FROM THIS DATE:

Previous cancer history increases chances of clotting disorders after knee surgery, study suggests

2011-07-10
SAN DIEGO, CA – A history of cancer was a significant risk factor for developing blood clotting issues following knee arthroscopy, according to a study being presented at the American Orthopaedic Society for Sports Medicine's Annual Meeting in San Diego. Researchers from the Mayo Clinic in Rochester, Minnesota analyzed the records of more than 12,000 patients who had undergone the common knee procedure. "A history of malignancy has not been widely recognized as a significant risk factor for developing a VTE (venous thromboembolytic event) following knee arthroscopy," ...

Ancestry of polar bears traced to Ireland

Ancestry of polar bears traced to Ireland
2011-07-10
An international team of scientists has discovered that the female ancestor of all living polar bears was a brown bear that lived in the vicinity of present-day Britain and Ireland just prior to the peak of the last ice age -- 20,000 to 50,000 years ago. Beth Shapiro, the Shaffer Associate Professor of Biology at Penn State University and one of the team's leaders, explained that climate changes affecting the North Atlantic ice sheet probably gave rise to periodic overlaps in bear habitats. These overlaps then led to hybridization, or interbreeding -- an event that caused ...

A gene implicated in speech regulates connectivity of the developing brain

2011-07-10
Foxp2, a gene involved in speech and language, helps regulate the wiring of neurons in the brain, according to a study which will be published on July 7th in the open-access journal PLoS Genetics. The researchers identified this functional link by first identifying the major targets of Foxp2 in developing brain tissue and then analysing the function of relevant neurons. Foxp2 codes for a regulatory protein that provides a window into unusual aspects of brain function. In 2001, scientists discovered that mutations of the human gene cause a rare form of speech and language ...

To combat deadly brain cancer, target the stem cells

2011-07-10
Researchers have uncovered a new target that could stop the growth of glioblastoma, a deadly form of brain cancer. In the July 8th issue of the journal Cell, a Cell Press publication, a new study identifies an enzyme found in glioma stem cells that allows them to grow and seed tumors. Importantly, normal stem cells, including those in the brain, don't appear to share that same dependency. "When thinking about therapeutics [targeting cancer stem cells], you have to be careful that you aren't interfering with normal stem cells," said Christine Eyler of the Cleveland Clinic. ...

With climate changes, polar bear and brown bear lineages intertwine

2011-07-10
Polar bears' unique characteristics allow them to survive in one of the most extreme environments on Earth, but that survival is now threatened as rising temperatures and melting ice reshape the Arctic landscape. Now it appears that the stress of climate change, occurring both long ago and today, may be responsible for surprising twists in the bears' history and future as well. According to DNA evidence reported in the July 7th Current Biology, a Cell Press publication, polar bears and brown bears have mated successfully many times in the last 100,000 years. As a result ...

Stem cell injections may offer hope to patients with no other options

2011-07-10
An injection of stem cells into the heart could offer hope to many of the 850,000 Americans whose chest pain doesn't subside even with medicine, angioplasty or surgery, according to a study in Circulation Research: Journal of the American Heart Association. Patients who received the new treatment reported half as many chest pain episodes and improved exercise capability compared to those who received a placebo. The study was the first randomized, controlled trial of stem-cell therapy to show significant improvements in both chest pain and exercise tolerance – the two ...

Sex works thanks to ever-evolving host, parasite relationships

2011-07-10
BLOOMINGTON, Ind. -- It seems we may have parasites to thank for the existence of sex as we know it. Indiana University biologists have found that, although sexual reproduction between two individuals is costly from an evolutionary perspective, it is favored over self-fertilization in the presence of coevolving parasites. Sex allows parents to produce offspring that are more resistant to the parasites, while self-fertilization dooms populations to extinction at the hands of their biological enemies. The July 8 report in Science, "Running with the Red Queen: Host-Parasite ...

Unexpected cell repairs the injured spinal cord

2011-07-10
Lesions to the brain or spinal cord rarely heal fully, which leads to permanent functional impairment. After injury to the central nervous system (CNS), neurons are lost and largely replaced by a scar often referred to as the glial scar based on its abundance of supporting glial cells. Although this process has been known to science for over a century, the function of the scar tissue has long been disputed. However, there are indications that it stabilizes the tissue and that it inhibits the re-growth of damaged nerve fibres. In this present study, Professor Jonas Frisén ...

Heart disease and stroke worldwide tied to national income

2011-07-10
An analysis of heart disease and stroke statistics collected in 192 countries by the World Health Organization (WHO) shows that the relative burden of the two diseases varies widely from country to country and is closely linked to national income, according to researchers at the University of California, San Francisco. Reporting this week in the journal Circulation, the UCSF scientists found that developing countries tend to suffer more death and disability by stroke than heart disease – opposite the situation in the United States and other countries with higher national ...

Lithosphere highlights: New research posted July 7

2011-07-10
Boulder, CO, USA – Highlights for articles published online 7 July 2011 are provided below. Keywords include: Coast Mountains batholith, Anderson Reservoir, Canada, Alaska, Chugach terrane, Valdez Group, Basin and Range province, and Sierra Nevada. LITHOSPHERE is now regularly posting pre-issue publication content -- finalized papers ready to go to press and not under embargo. GSA invites you to sign up for e-alerts (http://www.gsapubs.org/cgi/alerts) or RSS feeds (http://lithosphere.gsapubs.org/rss/) to have access to new journal content as soon as it is posted online. ...

LAST 30 PRESS RELEASES:

Bug beats: caterpillars use complex rhythms to communicate with ants

High-risk patients account for 80% of post-surgery deaths

Celebrity dolphin of Venice doesn’t need special protection – except from humans

Tulane study reveals key differences in long-term brain effects of COVID-19 and flu

The long standing commercialization challenge of lithium batteries, often called the dream battery, has been solved.​

New method to remove toxic PFAS chemicals from water

The nanozymes hypothesis of the origin of life (on Earth) proposed

Microalgae-derived biochar enables fast, low-cost detection of hydrogen peroxide

Researchers highlight promise of biochar composites for sustainable 3D printing

Machine learning helps design low-cost biochar to fight phosphorus pollution in lakes

Urine tests confirm alcohol consumption in wild African chimpanzees

Barshop Institute to receive up to $38 million from ARPA-H, anchoring UT San Antonio as a national leader in aging and healthy longevity science

Anion-cation synergistic additives solve the "performance triangle" problem in zinc-iodine batteries

Ancient diets reveal surprising survival strategies in prehistoric Poland

Pre-pregnancy parental overweight/obesity linked to next generation’s heightened fatty liver disease risk

Obstructive sleep apnoea may cost UK + US economies billions in lost productivity

Guidelines set new playbook for pediatric clinical trial reporting

Adolescent cannabis use may follow the same pattern as alcohol use

Lifespan-extending treatments increase variation in age at time of death

From ancient myths to ‘Indo-manga’: Artists in the Global South are reframing the comic

Putting some ‘muscle’ into material design

House fires release harmful compounds into the air

Novel structural insights into Phytophthora effectors challenge long-held assumptions in plant pathology

Q&A: Researchers discuss potential solutions for the feedback loop affecting scientific publishing

A new ecological model highlights how fluctuating environments push microbes to work together

Chapman University researcher warns of structural risks at Grand Renaissance Dam putting property and lives in danger

Courtship is complicated, even in fruit flies

Columbia announces ARPA-H contract to advance science of healthy aging

New NYUAD study reveals hidden stress facing coral reef fish in the Arabian Gulf

36 months later: Distance learning in the wake of COVID-19

[Press-News.org] Graft size and patient age may be predictor of need for future ACL revisions