PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

People in poorer neighborhoods have higher risk of sudden cardiac arrest

2011-09-13
(Press-News.org) Sudden cardiac arrest was higher among people living in poorer neighbourhoods in several US and Canadian cities, and the disparity was particularly evident among people under age 65, found a study in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/site/embargo/cmaj101512.pdf.

Sudden cardiac arrest accounts for up to 63% of deaths annually from cardiac diseases in the United States. Socioeconomic status is a predictor of many health-related conditions, including death and heart disease. This study examined a potential link between socioeconomic status and sudden cardiac arrest in more than one community.

A team of researchers in the US and Canada looked at data on 9235 sudden cardiac arrests in seven cities: four in the US: Dallas, Texas; Pittsburgh, Pennsylvania; Portland, Oregon; Seattle–King County, Washington; and three in Canada: Ottawa and Toronto, Ontario; and Vancouver, British Columbia.

The researchers looked at people who had cardiac arrests at home, a nursing home or assisted-living facility. They used census tract data on household incomes for the location of cardiac arrests to determine socioeconomic status.

"The incidence of sudden cardiac arrest was significantly higher in the neighbourhoods of lowest versus highest socioeconomic status in six of the seven metropolitan areas studied," writes Dr. Sumeet Chugh, Cedars-Sinai Medical Center, with coauthors.

Median household income was $50 000 to $63 000 US dollars, with income in the lowest socioeconomic group ranging from $30 000 to $41 000 and in the highest socioeconomic group from $72 000 to $97 000. In Pittsburgh, incomes were significantly lower ($21 000 and $54 000 respectively.)

"At all seven sites, disparities in the incidence of sudden cardiac arrest across socioeconomic quartiles were greatest among people less than 65 years old. Compared with the incidence in the highest quartile, the incidence in the lowest quartile was two- to fourfold greater in the US sites, and up to threefold greater in the Canadian sites," they write. "As with all ages combined, disparities across socioeconomic quartiles among people younger than 65 were significant at all sites except Ottawa." Compared with the disparities among younger people, the disparities among people 65 and older were less pronounced in in the US cities and Toronto.

The trend for higher cardiac arrests increased as median income dropped and was particularly noticeable among people under 65 years of age and stronger in the US cities than in the Canadian cities. The authors state that the exact reasons for US–Canadian differences need further investigation, but data from other studies indicate that one possible explanation is Canadians' access to universal health care; which may mean they have had preventive care for cardiac issues, compared with Americans who may not seek care because of cost, particularly those younger than 65 and not yet eligible for Medicare.

"Our results showing a younger mean age of sudden cardiac arrest in the United States may be consistent with more poorly controlled cardiovascular disease," state the authors.

They conclude that population-level interventions for people in low income neighbourhoods and better access to preventive health care may help to address these disparities.

In a related commentary http://www.cmaj.ca/site/embargo/cmaj111245.pdf, Dr. Heikki Huikuri, Institute of Clinical Medicine, University of Oulu, Finland, writes "this study should inform the decisions of politicians and managers of health care systems as they institute health care reforms, recognizing that sudden cardiac arrest is the single most common cause of death in western societies."

INFORMATION:

END



ELSE PRESS RELEASES FROM THIS DATE:

Cardiovascular drug may offer new treatment for some difficult types of leukemia

Cardiovascular drug may offer new treatment for some difficult types of leukemia
2011-09-13
INDIANAPOLIS – A drug now prescribed for cardiovascular problems could become a new tool in physicians' arsenals to attack certain types of leukemia that so far have evaded effective treatments, researchers say. The drug, Fasudil, has been used to treat stroke patients because it is a vasodilator, meaning it dilates blood vessels. However, its potential in leukemia emerged because its method of action is blocking the activity of a protein called Rho kinase, or ROCK. ROCK, which plays a role in a variety of cellular activities, attracted the attention of the national ...

1 in 5 Canadians has metabolic syndrome

2011-09-13
Approximately one in five Canadians has metabolic syndrome — a combination of risk factors for diabetes and heart disease — according to a study in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/site/embargo/cmaj110070.pdf. Metabolic syndrome increases the risk of heart disease twofold and includes a combination of three or more of the following five conditions: abdominal obesity, high triglycerides (high blood fat), low HDL cholesterol, high blood pressure or impaired glucose tolerance. The study looked at data from cycle 1 ...

BVES butts heads with colorectal cancer

2011-09-13
Once a cancer gains the ability to invade local tissues and spread to a distant site it becomes much harder to treat. A team of researchers, led by Min Chang and Christopher Williams, at Vanderbilt University School of Medicine, Nashville, has now identified the protein BVES as a suppressor of colorectal cancer progression to this dangerous state, leading them to suggest that BVES could be a therapeutic or preventative target in colorectal cancer. Cancers originating from cells covering any of the external and internal surfaces of the body (epithelial cells) are known ...

JCI online early table of contents: Sept. 12, 2011

2011-09-13
EDITOR'S PICK: BVES butts heads with colorectal cancer Once a cancer gains the ability to invade local tissues and spread to a distant site it becomes much harder to treat. A team of researchers, led by Min Chang and Christopher Williams, at Vanderbilt University School of Medicine, Nashville, has now identified the protein BVES as a suppressor of colorectal cancer progression to this dangerous state, leading them to suggest that BVES could be a therapeutic or preventative target in colorectal cancer. Cancers originating from cells covering any of the external and internal ...

Enzyme might be target for treating smoking, alcoholism at same time

Enzyme might be target for treating smoking, alcoholism at same time
2011-09-13
An enzyme that appears to play a role in controlling the brain's response to nicotine and alcohol in mice might be a promising target for a drug that simultaneously would treat nicotine addiction and alcohol abuse in people, according to a study by researchers at the Ernest Gallo Clinic and Research Center, affiliated with the University of California, San Francisco. Over the course of four weeks, mice genetically engineered to lack the gene for protein kinase C (PKC) epsilon consumed less of a nicotine-containing water solution than normal mice, and were less likely ...

Lung cancer signatures in blood samples may aid in early detection

2011-09-13
Lung cancer is one of the most common and deadly types of cancer. Mouse models of lung cancer recapitulate many features of the human disease and have provided new insight about cancer development, progression and treatment. Now, a new study published by Cell Press in the September 13th issue of the journal Cancer Cell identifies protein signatures in mouse blood samples that reflect lung cancer biology in humans. The research may lead to better monitoring of tumor progression as well as blood based early detection strategies for human lung cancer that could have a substantial ...

Blacks develop high blood pressure one year faster than whites

2011-09-13
African-Americans with prehypertension develop high blood pressure a year sooner than whites, according to research reported in Hypertension: Journal of the American Heart Association. Blacks with prehypertension also have a 35 percent greater risk of progressing to high blood pressure than whites, according to health records of 18,865 adults 18 to 85. Prehypertension is blood pressure ranging between 120/80 mm Hg and 139/89 mm Hg. Hypertension is 140/90 mm Hg or higher. Previous research has shown that coronary heart disease, stroke and high blood pressure are more ...

Torrance Cosmetic Dentist, Dr. Mondavi, Offers Cutting Edge Techniques for Teeth Whitening to Patients

Torrance Cosmetic Dentist, Dr. Mondavi, Offers Cutting Edge Techniques for Teeth Whitening to Patients
2011-09-13
Even with the summer beginning to wind down, dental patients from Torrance, CA are finding a new reason to smile this fall. Torrance cosmetic dentist, Dr. Mondavi, and his staff have begun utilizing cutting edge techniques to offer patients the brightest, straightest, and healthiest smiles of their lives. Many have come to fret and obsess over the appearance of their teeth. A beautiful smile will lead to confidence that will follow an individual around everywhere that they go. On the opposite end of the spectrum, those who feel as if their teeth are not as bright or ...

Breast cancer patients with BRCA gene diagnosed almost 8 years earlier than generation before

2011-09-13
Houston, TX – Women with a deleterious gene mutation are diagnosed with breast cancer almost eight years earlier than relatives of the previous generation who also had the disease and/or ovarian cancer, according to new research from The University of Texas MD Anderson Cancer Center. The findings, published online in Cancer and updated since first presented at the 2009 Breast Cancer Symposium, could have an impact on how women at highest risk for the disease are counseled and even screened in the future, explained Jennifer Litton, M.D., assistant professor in MD Anderson's ...

Day/night cycle even more important to life than previously suspected

2011-09-13
Researchers at USC were surprised recently to discover just how much the rising and setting of the sun drives life on Earth – even in unexpected places. Their findings, which appear this month in the Proceedings of the National Academy of Sciences, "speak volumes to the evolution of life on Earth," according to USC scientist Andrew Y. Gracey. "Everything is tied to the rotation of the planet," he said. In all organisms, a certain amount of gene expression (the process by which products are created from the blueprint contained in genes) is rhythmic. In creatures ...

LAST 30 PRESS RELEASES:

Casual teachers left behind: New study calls for better induction and support in schools

Adapting to change is the real key to unlocking GenAI’s potential, ECU research shows 

How algae help corals bounce back after bleaching 

Decoding sepsis: Unraveling key signaling pathways for targeted therapies

Lithium‑ion dynamic interface engineering of nano‑charged composite polymer electrolytes for solid‑state lithium‑metal batteries

Personalised care key to easing pain for people with Parkinson’s

UV light holds promise for energy-efficient desalination

Scientists discover new way to shape what a stem cell becomes

Global move towards plant-based diets could reshape farming jobs and reduce labor costs worldwide, Oxford study finds

New framework helps balance conservation and development in cold regions

Tiny iron minerals hold the key to breaking down plastic additives

New study reveals source of rain is major factor behind drought risks for farmers

A faster problem-solving tool that guarantees feasibility

Smartphones can monitor patients with neuromuscular diseases

Biomaterial vaccines to make implanted orthopedic devices safer

Semaglutide, tirzepatide, and dulaglutide have similar gastrointestinal safety profiles in clinical settings

Neural implant smaller than salt grain wirelessly tracks brain

Large brains require warm bodies and big offspring

Team’s biosensor technology may lead to breath test for lung cancer

Remote patient monitoring boosts primary care revenue and care capacity

Protein plays unexpected dual role in protecting brain from oxidative stress damage

Fermentation waste used to make natural fabric

When speaking out feels risky

Scientists recreate cosmic “fireballs” to probe mystery of missing gamma rays

Turning on an immune pathway in tumors could lead to their destruction

Tiles, leaves and cotton strips for measuring river health

Exploring the relationship between sleep and diet

Sex differences in gambling rats

From charged polymers to life-saving innovations

Building a safer future: 40+ experts chart roadmap to reduce firearm harms by 2040

[Press-News.org] People in poorer neighborhoods have higher risk of sudden cardiac arrest