(Press-News.org) Sophia Antipolis, Wednesday 22 February 2012: The next Joint European CVD Prevention Guidelines, scheduled for publication later this year at EuroPRevent 2012, will be shorter, tighter and supported by fewer references. The aim, says Professor Joep Perk, Chairperson of the Task Force of the fifth edition, is a set of guidelines whose recommendations can be readily applied and whose evidence is unequivocal. "If we had picked up where we left off with the fourth edition guidelines, we'd have ended up with a 150-page document and 2000 references," says Perk. "And with that we'd have reached a dead-end."
Behind the rethink lies a benchmarking study which has tested the penetration and application of the Joint Societies' fourth Guidelines on CVD Prevention and concluded that "substantial progress has been made" in implementing the guidelines, but that many countries "have struggled with the task".(1) The conclusions were based on interviews with representatives of national organisations active in CVD prevention from each of 13 countries, to reflect "the enablers" and the barriers to the guidelines' full implementation. The 13 countries were Estonia, France, Germany, Ireland, Italy, the Netherlands, Norway, Poland, Romania, Russia, Spain, Sweden, and the UK.
"Implementation is a key step in the development of all clinical guidelines," explains Perk. "Without dissemination, guidelines will remain ineffective and of little more than academic interest. We wanted our next guidelines to really have an impact, and we were very sensitive to the difficulties many countries have clearly had in applying previous recommendations." The fifth European Guidelines on CVD Prevention will be published in May and have been produced by a joint Task Force of the ESC and eight other European societies.
One of the benchmarking investigators, Dr Karen Morgan from the Royal College of Surgeons in Dublin, Ireland, agrees that the value of the next European guidelines will depend on how their recommendations are transferred into daily practice - but she acknowledged that progress in disease prevention according to the fourth version of the guidelines has been varied throughout Europe.(2) "So the challenge for the next edition," says Karen, "is to provide guidelines which are sufficiently detailed but still short and easily accessible in a number of languages and formats, so as to engage health professionals in their implementation."
The benchmarking interviews and analysis found that ten of the 13 countries had made some use of the fourth guidelines, which the investigators identified according to three definitions:
Adoption as national guidelines with local adaptation, mainly the adjustment of risk charts to national data (Italy, Poland, Romania, Russia, and Spain)
Incorporation into national guidelines along with guidelines from other sources (Estonia, Germany, and the Netherlands)
Co-existence with national guidelines developed by the health authorities (France and Sweden).
In Ireland, the Joint CVD Prevention Guidelines were used alongside guidelines from other sources, while in Norway and the UK other guidelines altogether were applied. All countries except Ireland and Norway had secured health ministry support for the joint guidelines.
However, while the framework for implementation of the guidelines seemed secured, active health authority support was not always apparent. For example, interviewees noted several factors which prevented governments from pursuing their prevention initiatives more vigorously, such as ideological beliefs in personal responsibility for lifestyle, inability to commit funding to support prevention activities, a tacit need to maintain the revenues from taxes on tobacco and alcohol, and the commercial interests of the tobacco, agriculture, and food industries in local economies.
However, there were other everyday barriers too, not least that physicians, faced everyday with managing acute and chronic disease, "undervalued prevention". Many interviewees also said that the guidelines themselves were simply too dense (more than 100 pages in the full version) for everyday observance - and that risk stratification according to the SCORE system still required more country-specific versions.
So now, as a result of the benchmarking study, which the Task Force has been aware of throughout its duration, the new guidelines have adopted several suggestions made by the investigators to improve implementation. These, said Perk, include a single-page quick-reference format and making the pocket version freely available. The Task Force has also developed a range of questions for CME credits derived from the new guidelines.
However, when published in May - in the European Heart Journal - and presented that same month at the EuroPRevent 2012 congress in Dublin, the fifth edition of the guidelines will have a whole new look and feel: just fifty pages and 150 references. "We've taken the study's comments to heart," says Perk. "Implementation is the key to the guidelines' success, and that's what we're aiming for."
The benchmarking study did, however, find an overall positive attitude towards the concept of uniform prevention guidelines across Europe, with ready acknowledgement of the need for preventive measures at both the clinical and population levels. Already, the study noted, such guidelines have had a major impact, and, at the specific level of their development, interviewees were "satisfied with their scope, credibility and evidence base".
INFORMATION:
Authors
ESC Press Office
Tel: +33 (0) 4 92 94 86 27
Fax: +33 (0) 4 92 94 86 69
Email: press@escardio.org
REFERENCES
1. Morgan K, Burke H, McGee H. Benchmarking progress in the implementation of the Fourth Joint Societies' Task Force Guidelines on the Prevention of Cardiovascular Disease in Clinical Practice. Eur J Cardiovasc Prev Rehabil 2012; DOI: 10.1177/2047487311433858.
2. Graham I, Atar D, Borch-Johnsen K, et al. European guidelines on cardiovascular disease prevention in clinical practice: full text. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (con- stituted by representatives of nine societies and by invited experts). Eur J Cardiovasc Prev Rehabil 2007; 14(2 Suppl): S1–S113.
About the European Society of Cardiology (ESC)
The European Society of Cardiology (ESC) represents more than 71,200 cardiology professionals across Europe and the Mediterranean. Its mission is to reduce the burden of cardiovascular disease in Europe.
http://www.escardio.org/
END
The offspring of women who were given micronutrient supplements (minerals needed in small quantities, such as iron, iodine and vitamin A) before they became pregnant had gene modifications at birth as well as when they were tested at 9 months.
The changes to the genes, called methylation, have previously been associated with the development of the immune system, although this study did not provide direct evidence that the activity of these genes has changed. The research, funded by the BBSRC, was published today in the journal Human Molecular Genetics in advance online ...
An international research, involving the participation of the Spanish National Research Council (CSIC), provides a new perspective on the jellyfish proliferation in world's oceans. This phenomenon has noticeably impacted on beaches around the world in recent years and has provoked the concerns of fishermen and bathers. However, according to the group of experts leading this new research, there are no "conclusive evidences" that point to global increase in jellyfish population.
The news rise in Mass Media on jellyfish blooms and the discrepancies in climate and science ...
Criminal gangs are increasingly using the internet to market life-threatening counterfeit medicines and some have even turned up in legitimate outlets such as pharmacies, according to a review led by Dr Graham Jackson, editor of IJCP, the International Journal of Clinical Practice, and published in the March edition.
Latest estimates suggest that global sales of counterfeit medicines are worth more than $75 billion, having doubled in just five years between 2005 and 2010. Numerous studies have also reported large numbers of websites supplying prescription only drugs without ...
Texting while driving increases the likelihood of a car accident or crash. The Alaska legislature passed a law in 2008 that it thought made texting and driving a crime, but the ambiguous language has raised questions from judges across the state.
A bill has been introduced to clarify the language and make it clear that texting while driving is prohibited in Alaska.
The problem with the law is how it described texting. It currently states:
"A person commits the crime of driving with a screen device operating if the person is driving a motor vehicle, a the vehicle ...
Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) have studied for the first time the response of human NK cells (Natural Killer) against porcine chondrocytes (cartilage cells).
The results of the research, published in The Journal of Immunology, indicate that these cells, characteristic of the innate immune system, play an important role in the rejection of xenotransplantation (transplantation from another species) of porcine chondrocytes.
NK cells
Together with neutrophils and macrophages, NK cells are part of the first line of cellular defence ...
Researchers from the University of the Basque Country (UPV/EHU, Spain) have been the first to discover the presence of certain aldehydes in food, which are believed to be related to some neurodegenerative diseases and some types of cancer. These toxic compounds can be found in some oils, such as sunflower oil, when heated at a suitable temperature for frying.
"It was known that at frying temperature, oil releases aldehydes that pollute the atmosphere and can be inhaled, so we decided to research into whether these remain in the oil after they are heated, and they do" ...
Sudden cardiac death is a risk for patients with heart failure because the calcium inside their heart cells is not properly controlled and this can lead to an irregular heartbeat. New findings published in PLoS ONE, which reveal mechanisms that underlie this life-threatening risk, provide new possibilities for fighting it.
The study, led by researchers from the University of Bristol's School of Physiology and Pharmacology, show how two individual but very similar proteins cooperatively adjust the amount of calcium inside the heart cells, and how this dual regulation may ...
Can animals' survival instincts shed additional light on what we know about human emotion? New York University neuroscientist Joseph LeDoux poses this question in outlining a pioneering theory, drawn from two decades of research, that could lead to a more comprehensive understanding of emotions in both humans and animals.
In his essay, which appears in the journal Neuron, LeDoux proposes shifting scientific focus "from questions about whether emotions that humans consciously feel are also present in other animals and towards questions about the extent to which circuits ...
A new study by researchers at The University of Nottingham has proved that assessing family medical history is a significant tool in helping GPs spot patients at high risk of heart disease and its widespread use could save lives.
Previous research has suggested that family history can be an indicator of a patient's risk of heart disease but at present family medical details are not systematically collected and used by GPs in cardiovascular risk assessment.
This first-ever clinical investigation into systematically collecting family history as part of cardiovascular ...
Amsterdam, February 22, 2012 – Functional foods containing bacteria with beneficial health effects, or probiotics, have long been consumed in Northern Europe and are becoming increasingly popular elsewhere. To be of benefit, however, the bacteria have to survive in the very hostile environment of the digestive tract. A group of scientists from the Norwegian University of Life Sciences in Ås, Norway have developed a "model gastric system" for evaluating the survival of bacteria strains in the human digestive system, and determined that some bacteria strains survive better ...