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Listen to neurons in your own backyard with the SpikerBox

2012-03-22
(Press-News.org) Amateurs have a new tool for conducting simple neuroscience experiments in their own garage: the SpikerBox. As reported in the Mar. 21 issue of the open access journal PLoS ONE, the SpikerBox lets users amplify and listen to neurons' electrical activity – like those in a cockroach leg or cricket torso – and is appropriate for use in middle or high school educational programs, or by amateurs.

The work was a project from Backyard Brains, a start-up company focused on developing neuroscience educational resources. In the paper, the authors, Timothy Marzullo and Gregory Gage, describe a sample experiment using a cockroach leg stuck with two needles and monitoring the electrical signals. They also provide instructions for using the SpikerBox to answer specific experimental questions, like how neurons carry information about touch, how the brain tells muscles to move, and how drugs affect neurons, and an online portal provides further instructional materials. These are just a few examples of the many ways this tool can be used.

"Our mission is to lower the barrier-to-entry for students interested in learning about the brain. We hope our manuscript finds its way into the hands of high school teachers around the world", says Dr. Marzullo.

INFORMATION:

Citation: Marzullo TC, Gage GJ (2012) The SpikerBox: A Low Cost, Open-Source BioAmplifier for Increasing Public Participation in Neuroscience Inquiry. PLoS ONE 7(3): e30837. doi:10.1371/journal.pone.0030837

Financial Disclosure: Support for the SpikerBox development and outreach efforts were primarily provided by the National Institutes of Mental Health Small Business Innovation Research grant #1R43MH093334-01: ''Backyard Brains: Bringing Neurophysiology into Secondary Schools'' and the Kauffman Foundation Post Doctoral Entrepreneurial Fellowship. Additional support was provided by Cell Press Anuradha Rao Memorial Travel Award, the Society for Neuroscience Next Generation Award, the SquareOne Education Network, and the University of Michigan Center for Entrepreneurship ''Dare to Dream'' Grant. The financial support for publication in PLoS ONE was subsidized through the Kickstarter Project ''Backyard Brains: Operation Publication.'' Funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing Interest Statement: Authors TM and GG are both owners and employees of Backyard Brains, Inc. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Disclaimer: This press release refers to upcoming articles in PLoS ONE. The releases have been provided by the article authors and/or journal staff. Any opinions expressed in these are the personal views of the contributors, and do not necessarily represent the views or policies of PLoS. PLoS expressly disclaims any and all warranties and liability in connection with the information found in the release and article and your use of such information.

About PLoS ONE

PLoS ONE is the first journal of primary research from all areas of science to employ a combination of peer review and post-publication rating and commenting, to maximize the impact of every report it publishes. PLoS ONE is published by the Public Library of Science (PLoS), the open-access publisher whose goal is to make the world's scientific and medical literature a public resource.

All works published in PLoS ONE are Open Access. Everything is immediately available—to read, download, redistribute, include in databases and otherwise use—without cost to anyone, anywhere, subject only to the condition that the original authors and source are properly attributed. For more information about PLoS ONE relevant to journalists, bloggers and press officers, including details of our press release process and our embargo policy, see the everyONE blog at http://everyone.plos.org/media.

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[Press-News.org] Listen to neurons in your own backyard with the SpikerBox