PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Research sheds new light on extra help for smokers trying to quit

2012-03-26
(Press-News.org) A major research trial to test whether extra support for smokers calling an NHS quitline - on top of what is already offered by the service - has found the additional help does not improve success rates for quitting the habit.

The pilot scheme offered smokers additional help in the form of free nicotine patches and extra telephone counselling from the English National Quitline. The Department of Health and UK Centre for Tobacco Control Studies (UKCTCS)-funded study led by The University of Nottingham's UK Centre for Tobacco Control Studies has just been published in the online version of the British Medical Journal.

The work was carried out to establish whether the tried and tested support from the quitline could be improved to help more people stop smoking. The trial also examined whether the offer of free nicotine replacement therapy made to quitline callers increases the numbers of smokers who give up for good.

Leading the study, Professor Tim Coleman of UKCTCS, said: "This important trial has shed useful light on how telephone quitlines can be used to help smokers wanting to quit. I think the results highlight just how hard it is for most people to break their addiction to tobacco and just how powerful and damaging a drug this is. On the basis of this study, giving out free nicotine patches and more intensive telephone counselling through the English national quitline just doesn't seem to work. It brings into sharp relief the need to find other ways of using quitlines help smokers give up and so to reduce the terrible effects smoking has on people's lives and the costly burden to the NHS."

Smoking remains the single most important avoidable cause of illness and death and research into smoking cessation is a top public health priority in the UK. This latest study by UKCTCS set out to compare the effectiveness of a package of extra support offered to smokers with the standard support offered through the English NHS Smoking Helpline.

The researchers carried out a parallel four group (2x2), randomised controlled trial among 2,591 non-pregnant smokers who called the English NHS smoking helpline between February 2009 and February 2010. Each smoker was randomly assigned to one of four groups:

Standard support- NHS Stop Smoking Services advice and access to helpline Standard support with free nicotine replacement therapy (NRT) Proactive support -consisting of extra and regular scheduled telephone and message support from helpline staff. Proactive support with free (NRT)

The proactive groups were contacted by counsellors before their agreed quit date, on the day itself, and then at 3,7,14 and 21 days after quitting. Counsellors were trained to use specially designed motivational interviewing techniques which were tailored to each stage of the quitting process. The support closely monitored the two proactive groups' progress, and offered counselling, encouragement and congratulations.

Trial follow up was carried out by a market research company who were blind to treatment allocations. They collected data by telephone at one and six months after quit dates. The primary outcome was self-reported, prolonged abstinence from smoking from the quit date to six months. Lapses of no more than five cigarettes in that period were allowed. Prolonged abstinence from the quit date and one month was also monitored with the same lapses permitted.

Analysis of the substantial bank of data recorded during the trial showed that at six months after quitting 18.9 per cent of the 59 per cent of participants who were contacted said they had managed not to smoke. Those whom the researchers were not able to contact were assumed to be smoking. Nearly 80 per cent of these agreed to give a breath test for carbon monoxide to validate their claim and 80 per cent of the tests proved they had quit successfully. Crucially no significant difference in success rates was observed between quit rates in the standard and proactive counselling groups or between those offered and not offered, NRT.

At one month after quit date higher follow-up rates were achieved (65.3 per cent of participants were contacted) but even with more complete data and the higher overall quit rates at one month (40.1 per cent), no significant differences were detected between the different intervention groups.

Overall the study has concluded that offering free nicotine patches or proactive counselling to smokers calling the English national smoking quitline was no more effective than the standard reactive quitline support which is currently on offer through the NHS. Quitlines can reach large numbers of smokers who are highly motivated to stop smoking . Consequently, future research needs to test other methods of providing cessation support to quitline callers so the most effective ways using quitlines can be discovered.

### More information is available from Professor Tim Coleman, School of Community Health Sciences/UKCTCS, University of Nottingham, on 44-115-823-0204, tim.coleman@nottingham.ac.uk; or Emma Rayner, Media Relations Manager, Communications, University of Nottingham on 44-115-951-5793, emma.rayner@nottingham.ac.uk


ELSE PRESS RELEASES FROM THIS DATE:

Non-narcotic pain medication is safe and effective after sinus surgery

2012-03-26
MAYWOOD, Il. -- Patients who have undergone sinus surgery can safely take an alternative pain medication that does not cause the side effects of narcotics such as fentanyl and Vicodin, a Loyola University Health System study has found. The alternative medication is ketorolac (brand name, Toradol). It is in the same class of nonsteroidal anti-inflammatory drugs as Advil and Aleve. Ketorolac does not cause the side effects that narcotic drugs cause, such as itching, nausea, vomiting, constipation and drowsiness, said Kevin Welch, MD, corresponding author of the study, published ...

Identifying acute myeloid leukemia gene mutations may indicate risk, best treatment

2012-03-26
TAMPA, Fla. – An international group of researchers, including those from Moffitt Cancer Center in Tampa, Fla., have published a paper in the March 14 issue of the New England Journal of Medicine reviewing the results of a study that analyzed mutations in 18 genes of 398 patients who had acute myeloid leukemia (AML). They found that several mutated genes predicted improved outcomes when patients with certain gene mutations were given high-dose induction chemotherapy. Their findings suggest that mutational profiling could potentially be used for both risk stratification ...

Marine forensics expert Richard Woytowich seeks to vindicate Titanic survivors' account

2012-03-26
Brooklyn, NY -- On the eve of the 100th anniversary of the Titanic's sinking, marine forensics expert Richard Woytowich will present a paper re-interpreting the statements made by survivors at the 1912 official inquiries into the disaster. Woytowich, a professor of computer engineering technology at New York City College of Technology (City Tech), will take into account what engineers and other technologists now know about how the ill-fated passenger liner broke apart on April 15, 1912. He will be presenting his research on April 4, 8 a.m., at the International Marine ...

A new test might facilitate diagnosis and drug development for Alzheimer's disease

2012-03-26
An international team of researchers have developed a new method for measurement of aggregated beta-amyloid – a protein complex believed to cause major nerve cell damage and dysfunction in Alzheimer's disease. The new method might facilitate diagnosis and detection as well as development of drugs directed against aggregated beta-amyloid. Alzheimer's disease (AD) is the most common cause of memory decline and dementia. According to the Alzheimer World Report 2011, today around 36 million people suffer from Dementia (around 20 - 25 million are Alzheimer's patients). These ...

New ORNL tool developed to assess global freshwater stress

2012-03-26
A new method to make better use of vast amounts of data related to global geography, population and climate may help determine the relative importance of population increases vs. climate change. While several recent studies suggest that much of the world is likely to experience freshwater shortages as the population increases and temperatures rise, determining the relative impact of each has been difficult. An Oak Ridge National Laboratory paper published in Computers & Geosciences outlines a process that might help. "Our work establishes a new method to couple geographic ...

'Bed-of-nails' breast implant deters cancer cells

Bed-of-nails breast implant deters cancer cells
2012-03-26
PROVIDENCE, R.I. [Brown University] -- One in eight women in the United States will develop breast cancer. Of those, many will undergo surgery to remove the tumor and will require some kind of breast reconstruction afterward, often involving implants. Cancer is an elusive target, though, and malignant cells return for as many as one-fifth of women originally diagnosed, according to the American Cancer Society. Would it be possible to engineer implant materials that might drive down that rate of relapse? Brown University biomedical scientists report some promising advances. ...

Huge hamsters and pint-sized porcupines thrive on islands

2012-03-26
DURHAM, N.C. -- From miniature elephants to monster mice, and even Hobbit-sized humans, size changes in island animals are well-known to science. Biologists have long believed that large animals evolving on islands tend to get smaller, while small animals tend to get bigger, a generalization they call "the island rule." A new study by researchers at Duke University and the National Evolutionary Synthesis Center in Durham, NC puts that old idea to the test in island and mainland rodents. "Some of the size changes observed in island animals are pretty dramatic," said ...

Researchers unveil robot jellyfish built on nanotechnology

2012-03-26
Researchers at The University of Texas at Dallas and Virginia Tech have created an undersea vehicle inspired by the common jellyfish that runs on renewable energy and could be used in ocean rescue and surveillance missions. In a study published this week in Smart Materials and Structures, scientists created a robotic jellyfish, dubbed Robojelly, that feeds off hydrogen and oxygen gases found in water. "We've created an underwater robot that doesn't need batteries or electricity," said Dr. Yonas Tadesse, assistant professor of mechanical engineering at UT Dallas and ...

Possible causes of sudden onset OCD in kids broadened

Possible causes of sudden onset OCD in kids broadened
2012-03-26
Criteria for a broadened syndrome of acute onset obsessive compulsive disorder (OCD) have been proposed by a National Institutes of Health scientist and her colleagues. The syndrome, Pediatric Acute-onset Neuropsychiatric Syndrome (PANS), includes children and teens that suddenly develop on-again/off-again OCD symptoms or abnormal eating behaviors, along with other psychiatric symptoms – without any known cause. PANS expands on Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcus (PANDAS), which is limited to a subset of cases traceable to ...

UN hits water target, but 1.8 billion people still drinking unsafe water, study shows

2012-03-26
Recent widespread news coverage heralded the success of a United Nations' goal of greatly improving access to safe drinking water around the world. But while major progress has been made, a new study from the University of North Carolina at Chapel Hill indicates that far greater challenges persist than headline statistics suggested. Earlier this month (March 6), UNICEF and the World Health Organization issued a report stating that the world had met the U.N.'s Millennium Development Goal target of halving the proportion of people without access to safe drinking water, ...

LAST 30 PRESS RELEASES:

ASH 2025: New study shows that patients can safely receive stem cell transplants from mismatched, unrelated donors

Protective regimen allows successful stem cell transplant even without close genetic match between donor and recipient

Continuous and fixed-duration treatments result in similar outcomes for CLL

Measurable residual disease shows strong potential as an early indicator of survival in patients with acute myeloid leukemia

Chemotherapy and radiation are comparable as pre-transplant conditioning for patients with b-acute lymphoblastic leukemia who have no measurable residual disease

Roughly one-third of families with children being treated for leukemia struggle to pay living expenses

Quality improvement project results in increased screening and treatment for iron deficiency in pregnancy

IV iron improves survival, increases hemoglobin in hospitalized patients with iron-deficiency anemia and an acute infection

Black patients with acute myeloid leukemia are younger at diagnosis and experience poorer survival outcomes than White patients

Emergency departments fall short on delivering timely treatment for sickle cell pain

Study shows no clear evidence of harm from hydroxyurea use during pregnancy

Long-term outlook is positive for most after hematopoietic cell transplant for sickle cell disease

Study offers real-world data on commercial implementation of gene therapies for sickle cell disease and beta thalassemia

Early results suggest exa-cel gene therapy works well in children

NTIDE: Disability employment holds steady after data hiatus

Social lives of viruses affect antiviral resistance

Dose of psilocybin, dash of rabies point to treatment for depression

Helping health care providers navigate social, political, and legal barriers to patient care

Barrow Neurological Institute, University of Calgary study urges “major change” to migraine treatment in Emergency Departments

Using smartphones to improve disaster search and rescue

Robust new photocatalyst paves the way for cleaner hydrogen peroxide production and greener chemical manufacturing

Ultrafast material captures toxic PFAS at record speed and capacity

Plant phenolic acids supercharge old antibiotics against multidrug resistant E. coli

UNC-Chapel Hill study shows AI can dramatically speed up digitizing natural history collections

OYE Therapeutics closes $5M convertible note round, advancing toward clinical development

Membrane ‘neighborhood’ helps transporter protein regulate cell signaling

Naval aviator turned NPS doctoral student earns national recognition for applied quantum research

Astronomers watch stars explode in real time through new images

Carbon-negative building material developed at Worcester Polytechnic Institute published in matter

Free radicals caught in the act with slow spectroscopy

[Press-News.org] Research sheds new light on extra help for smokers trying to quit