PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

New study quantifies the enormous cost of fragility fractures in Europe

Total economic burden estimated at 39 billion EUR; Hip fractures account for more than half of all costs

2012-03-26
(Press-News.org) Researchers at the European Congress of Osteoporosis & Osteoarthritis in Bordeaux have presented new data * which shows that the economic burden of fragility fractures in the 27 member states of the European Union far exceeds previous estimates, with hip fractures accounting for around 55% of costs.

The investigators used a population based model to estimate the economic burden of fractures in 2010, using data on facture incidence, costs for pharmaceutical prevention and post-fracture health care, mortality, and population size to estimate total costs. Data for hip, vertebral, wrist, "other fractures" were included and a societal perspective was used as far as possible. Costs were divided into cost of fractures occurring within the index year, cost of prior historic fractures that still are associated with costs, and cost of pharmaceutical prevention.

The total economic burden, including pharmaceutical prevention, of fractures in the European Union in 2010 was estimated at €39 billion EUR. The highest costs were in the EU's five largest countries – Germany (9.3 billion), Italy (7.2 billion), UK (5.6 billion), France (5 billion), Spain (2.9 billion).

The direct costs of treating new fractures accounted for €26 billion EUR, long-term fracture care €11 billion and pharmaceutical prevention only €2 billion. Excluding pharmaceutical prevention costs, hip, vertebral, wrist and "other fractures" comprised 55%, 5%, 1% and 38% of the economic burden respectively.

John A. Kanis, Professor Emeritus at the University of Sheffield, WHO Collaborating Centre, and lead author of the study, concluded, "We have found that pharmaceutical prevention of fractures only accounts for 2 billion EUR in expenditure – approximately 5% of the total cost burden of fractures. This small investment in prevention and treatment reflects the fact that osteoporosis, which is most often the underlying cause of fragility fractures, is neither being assessed nor treated in the majority of people at high risk."

The economic burden of fractures in the European Union is expected to grow as as the number of seniors increases in Europe. Studies have estimated that the number of fractures will more than double by 2050 unless preventive action is taken.

###* The economic burden of fractures in the European Union in 2010. Kanis JA, Compston J, Cooper C et al. Osteoporos Int Vol 23 (2012), Supplement 2 (Abstract 0C1)

ABOUT IOF The International Osteoporosis Foundation (IOF) is the world's largest nongovernmental organization devoted to the prevention, diagnosis and treatment of osteoporosis and related musculoskeletal diseases. IOF members – including committees of scientific researchers, patient, medical and research societies, and industry representatives from around the globe - share a common vision of a bone healthy future without fragility fractures. IOF now represents more than 200 societies in all regions of the world. http://www.iofbonehealth.org

ABOUT ESCEO The European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) is a non-profit organization, dedicated to a close interaction between clinical scientists dealing with rheumatic disorders, pharmaceutical industry developing new compounds in this field, regulators responsible for the registration of such drugs and health policy makers, to integrate the management of osteoporosis and osteoarthritis within the comprehensive perspective of health resources utilization. The objective of ESCEO is to provide practitioners with the latest clinical and economic information, allowing them to organize their daily practice, in an evidence-based medicine perspective, with a cost-conscious perception. http://www.esceo.org


ELSE PRESS RELEASES FROM THIS DATE:

Chris Thomson, Solicitor at Greene & Greene, Offers Advice to Those Thinking of Selling a Business

2012-03-26
Many buyers generate cash from trading and, rather than it earning only bank interest of, say, 3% use that cash to expand by buying other businesses. On average my team is successfully completing 9 or 10 sales every month. Start with tax advice and do the numbers Sellers can, with the right professional advice, pay no more than 10% tax on sale proceeds; a rate that compares favourably to income tax at 50%. So far so good, but work out what you are left with after paying tax. What return will you get on that capital? How does that compare to the income you now get ...

Researchers validate the potential of a protein for the treatment of type 2 diabetes

Researchers validate the potential of a protein for the treatment of type 2 diabetes
2012-03-26
Researchers at the Institute for Research in Biomedicine (IRB Barcelona) have discovered that deficiency of a single protein, Mitofusin 2, in muscle and hepatic cells of mice is sufficient to cause tissues to become insensitive to insulin, thus producing an increase in blood glucose concentrations. These are the two most common conditions prior to development of diabetes type 2. Published in this week's issue of Proceedings of the National Academy of Sciences (PNAS), the study validates Mitofusin 2 as a possible target for the treatment of diabetes type 2. "Resistance ...

Tom and Jerry Games Launches Two New Games

2012-03-26
Tom and Jerry Games, a free game website featuring entertainment inspired by some of the world's most beloved cartoons, has launched two new games, Tom and Jerry Iceball and Jerry Dressup. The two new games add even more depth to the stunning selection of games already present on the Tom and Jerry Games website, which allows parents and children to bond over activities based on animated characters that helped define the childhood of many of today's parents. The games featured on the website, including the new Tom and Jerry Iceball and Jerry Dressup, authentically channel ...

Biomarkers for autism discovered

2012-03-26
An important step towards developing a rapid, inexpensive diagnostic method for autism has been take by Uppsala University, among other universities. Through advanced mass spectrometry the researchers managed to capture promising biomarkers from a tiny blood sample. The study has just been published in the prestigious journal Nature Translational Psychiatry. There are no acknowledged biomarkers for autism today. Researchers at Berzelii Centre and the Science for Life Laboratory in Uppsala who, in collaboration with colleagues at Linnaeus University in Sweden and the Faculty ...

Study identifies genetic variants linked to fatty liver disease in obese children

2012-03-26
New research found the genetic variant Patatin-like phospholipase domain containing protein-3 (PNPLA3) acting in conjunction with the glucokinase regulatory protein (GCKR) is associated with increased susceptibility to fatty liver disease in obese children. The study, published in the March issue of Hepatology, a journal of the American Association for the Study of Liver Diseases, determined the PNPLA3 and GCKR single nucleotide polymorphisms (SNPs) were responsible for up to 39% of the hepatic fat content in this pediatric population. Obesity is a global health concern ...

Mario dash Games Launches Three New Games

2012-03-26
Mario Dash Games, a free gaming website offering interactive Flash games based on beloved Nintendo characters such as Mario, Luigi, Yoshi, and Wario, has introduced three new games to its roster: World of Mario, Mario Zombie Explode, and Mario Bubaboom. The three games are consistent with the mission of Mario Dash Games, which is to provide engaging, amusing online games without the cost of an expensive console or the need to buy separate games. Whether you have a few minutes to kill or an entire weekend washed out by rain, Mario Dash Games is an ideal way to beat boredom, ...

Danes top international health study

2012-03-26
Danish consumers are attracting attention in a new international study on healthy heating. More than 3,000 consumers from five European countries were asked whether they are willing to accept national economic interventions to promote healthy eating habits. The results are unequivocal: Danes have the most positive attitude towards economic interventions within the nutritional area, and are also willing to pay more to eat more healthily, says PhD student Jessica Aschemann-Witzel from Aarhus University, Business and Social Sciences, who is one of the architects of the ...

Archaeologists reconstruct diet of Nelson's Navy with new chemical analysis of excavated bones

2012-03-26
Salt beef, sea biscuits and the occasional weevil; the food endured by sailors during the Napoleonic wars is seldom imagined to be appealing. Now a new chemical analysis technique has allowed archaeologists to find out just how dour the diet of Georgian sailors really was. The team's findings, published in the American Journal of Physical Anthropology also reveal how little had changed for sailors in the 200 years between the Elizabethan and Georgian eras. The research, led by Professor Mark Pollard from the University of Oxford, focused on bones from 80 sailors who served ...

Synder Filtration to Exhibit Filtration at the International Cheese Technology Expo and ECOAT 2012 in April

Synder Filtration to Exhibit Filtration at the International Cheese Technology Expo and ECOAT 2012 in April
2012-03-26
As a leading supplier of membrane technology to the dairy and ecoat industries worldwide, Synder Filtration will be exhibiting at both the International Cheese Technology Expo and ECOAT 2012 next month. Visit booth #344 at the Cheese Expo and the exhibit hall at ECOAT 2012 to meet with Synder's friendly and experienced sales, engineering, and business development staff. Synder's representatives are excited to not only reconnect with current customers, but also forge new partnerships in quality and service. Both flagship products, such as membrane elements and anolyte technology ...

Astronomers put forward new theory on size of black holes

2012-03-26
Astronomers have put forward a new theory about why black holes become so hugely massive – claiming some of them have no 'table manners', and tip their 'food' directly into their mouths, eating more than one course simultaneously. Researchers from the UK and Australia investigated how some black holes grow so fast that they are billions of times heavier than the sun. The team from the University of Leicester (UK) and Monash University in Australia sought to establish how black holes got so big so fast. Their research is due to published in the Monthly Notices of ...

LAST 30 PRESS RELEASES:

Increase in alcohol deaths in England an ‘acute crisis’

Government urged to tackle inequality in ‘low-carbon tech’ like solar panels and electric cars

Moffitt-led international study finds new drug delivery system effective against rare eye cancer

Boston stroke neurologist elected new American Academy of Neurology president

Center for Open Science launches collaborative health research replication initiative

Crystal L. Mackall, MD, FAACR, recognized with the 2025 AACR-Cancer Research Institute Lloyd J. Old Award in Cancer Immunology

A novel strategy for detecting trace-level nanoplastics in aquatic environments: Multi-feature machine learning-enhanced SERS quantification leveraging the coffee ring effect

Blending the old and the new: Phase-change perovskite enable traditional VCSEL to achieve low-threshold, tunable single-mode lasers

Enhanced photoacoustic microscopy with physics-embedded degeneration learning

Light boosts exciton transport in organic molecular crystal

On-chip multi-channel near-far field terahertz vortices with parity breaking and active modulation

The generation of avoided-mode-crossing soliton microcombs

Unlocking the vibrant photonic realm: A new horizon for structural colors

Integrated photonic polarizers with 2D reduced graphene oxide

Shouldering the burden of how to treat shoulder pain

Stevens researchers put glycemic response modeling on a data diet

Genotype-to-phenotype map of human pelvis illuminates evolutionary tradeoffs between walking and childbirth

Pleistocene-age Denisovan male identified in Taiwan

KATRIN experiment sets most precise upper limit on neutrino mass: 0.45 eV

How the cerebellum controls tongue movements to grab food

It’s not you—it’s cancer

Drug pollution alters migration behavior in salmon

Scientists decode citrus greening resistance and develop AI-assisted treatment

Venom characteristics of a deadly snake can be predicted from local climate

Brain pathway links inflammation to loss of motivation, energy in advanced cancer

Researchers discover large dormant virus can be reactivated in model green alga

New phase of the immune response uncovered

Drawing board rather than salt shaker

Engineering invites submissions on AI for engineering

In Croatia’s freshwater lakes, selfish bacteria hoard nutrients

[Press-News.org] New study quantifies the enormous cost of fragility fractures in Europe
Total economic burden estimated at 39 billion EUR; Hip fractures account for more than half of all costs