PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Study finds 'overmanagement' of benign breast disease

2012-05-04
(Press-News.org) Contrary to current guidelines, women with benign breast biopsies do not need follow-up at six months; they may not need close surveillance at all, a new study shows.

The study, conducted at Moffitt Cancer Center in Tampa, FL, followed 388 patients for six, 12 and 24 months. No cancer was found in these patients at six and 12 months, said Shannon Reed, MD, one of the authors of the study. "Of the 197 follow-up examinations performed at 24 months, two women were positive for cancer in a different area than had been previously biopsied," said Dr. Reed. An annual mammogram, as part of regular preventive care, could replace the need for benign breast disease follow-up of these patients, said Dr. Reed

"The National Comprehensive Cancer Network guidelines recommend that patients with benign breast biopsies undergo follow-up (which can include imaging and a physical exam) every six to 12 months for one to two years," said Dr. Reed. However, "the low incidence of breast cancer occurring over two years may obviate close surveillance, thereby reducing radiation exposure to the patients, and reducing health care dollars," said Dr. Reed.

The close surveillance over the two year time period, led to more than 6% of these women having an additional biopsy performed, all of which were benign. This indicates "over-treatment" of these patients as well as "overmanagement," Dr. Reed said.

"The study results are changing the way we practice," said Dr. Reed. "We are recommending diagnostic imaging follow-up annually for two years, followed by a return to routine screening," she said.

The study will be presented May 3, 2012 at the American Roentgen Ray Society Annual Meeting in Vancouver, Canada.

INFORMATION:

About ARRS

The American Roentgen Ray Society (ARRS) was founded in 1900 and is the oldest radiology society in the United States. Its monthly journal, the American Journal of Roentgenology, began publication in 1906. Radiologists from all over the world attend the ARRS Annual Meeting to take part in instructional courses, scientific paper presentations and scientific and commercial exhibits related to the field of radiology. The Society is named after the first Nobel Laureate in Physics, Wilhelm Röentgen, who discovered the X-ray in 1895.

END



ELSE PRESS RELEASES FROM THIS DATE:

Increasing speed of Greenland glaciers gives new insight for rising sea level

Increasing speed of Greenland glaciers gives new insight for rising sea level
2012-05-04
Changes in the speed that ice travels in more than 200 outlet glaciers indicates that Greenland's contribution to rising sea level in the 21st century might be significantly less than the upper limits some scientists thought possible, a new study shows. "So far, on average we're seeing about a 30 percent speedup in 10 years," said Twila Moon, a University of Washington doctoral student in Earth and space sciences and lead author of a paper documenting the observations published May 4 in Science. The faster the glaciers move, the more ice and meltwater they release ...

Biologists turn back the clock to understand evolution of sex differences

Biologists turn back the clock to understand evolution of sex differences
2012-05-04
Sex differences account for some of the most of the spectacular traits in nature: the wild colours of male guppies, the plumage of peacocks, tusks on walruses and antlers on moose. Sexual conflict – the battle between males and females over mating – is thought to be a particularly potent force in driving the evolution traits that differ in males and females. However, the genetic processes responsible for producing such traits are not well understood, nor how they evolved from their simpler less elaborate ancestral forms. We tend to assume that each tiny step in evolution ...

Aged hematopoietic stem cells rejuvenated to be functionally younger

2012-05-04
CINCINNATI – Researchers have rejuvenated aged hematopoietic stem cells to be functionally younger, offering intriguing clues into how medicine might one day fend off some of the ailments of old age. Scientists at Cincinnati Children's Hospital Medical Center and the Ulm University Medicine in Germany report their findings online May 3 in the journal Cell Stem Cell. The paper brings new perspective to what has been a life science controversy – countering what used to be broad consensus that the aging of hematopoietic stem cells (HSCs) was locked in by nature and not reversible ...

The American College of Rheumatology issues guidelines for management of lupus nephritis

2012-05-04
The American College of Rheumatology (ACR) has issued newly created guidelines for the screening, treatment, and management of lupus nephritis—a severe manifestation of systemic lupus erythematosus (SLE) where the disease attacks the kidneys. Previously, only general guidelines for SLE existed for clinicians. The guidelines, available today in Arthritis Care & Research, are specific to lupus nephritis and include methods for identifying renal disease, newer therapies, and treatment of pregnant SLE patients with kidney involvement. The ACR estimates that up to 322,000 ...

Naturally blond hair in Solomon Islanders rooted in native gene, Stanford study finds

2012-05-04
STANFORD, Calif. — The common occurrence of blond hair among the dark-skinned indigenous people of the Solomon Islands is due to a homegrown genetic variant distinct from the gene that leads to blond hair in Europeans, according to a new study from the Stanford University School of Medicine. "This is one of the most beautiful examples to date of the mapping of a simple genetic trait in humans," said David Reich, PhD, a professor of genetics at Harvard University, who was not involved in the study. The study identifying the gene responsible for blond hair in the Solomon ...

Double duty: Versatile immune cells play dual roles in human skin

2012-05-04
A new study helps to resolve an ongoing controversy about whether Langerhans cells (LCs) in human skin function to suppress the immune response and promote tolerance to normal human skin and its "friendly" microbial flora or mobilize a lethal attack against harmful foreign invaders. The research, published online May 3rd in the journal Immunity by Cell Press, reveals that, depending on the situation, these versatile immune cells can perform either function. Adult human skin contains billions of resident immune cells called T cells that provide protection from invading ...

Treatment guidelines updated for aneurysmal subarachnoid hemorrhage

2012-05-04
Treatment guidelines updated for aneurysmal subarachnoid hemorrhage Patients who are diagnosed in the emergency room with a specific type of brain bleed should be considered for immediate transfer to a hospital that treats at least 35 cases a year, according to a new scientific statement from the American Heart Association/American Stroke Association. The Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage (aSAH) is published online in Stroke, an American Heart Association Journal. It updates guidelines issued in 2009. "Admission to high-volume centers ...

Pleasure eating triggers body's reward system and may stimulate overeating

2012-05-04
When eating is motivated by pleasure, rather than hunger, endogenous rewarding chemical signals are activated which can lead to overeating, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). The phenomenon ultimately affects body mass and may be a factor in the continuing rise of obesity. "'Hedonic hunger' refers to the desire to eat for pleasure, and to enjoy the taste, rather than to restore the body's energy needs,"says Palmiero Monteleone, MD, of the University of Naples SUN in Italy ...

Some women may be genetically predisposed to smoking-related hot flashes

2012-05-04
Women who smoke and carry specific variations in the genes that impact their metabolism are at higher risk of developing hot flashes in comparison with smokers who do not carry these gene variants, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology and Metabolism (JCEM). Previous studies have shown that smoking is associated with earlier onset of menopause, increased odds of hot flashes and risk of postmenopausal osteoporosis. The current study aimed to explore which smokers have the highest risk of hot flashes ...

Measuring progesterone receptor expression to improve hormone-receptor-positive cancer management

2012-05-04
American and Spanish researchers have found potential ways for doctors to improve the treatment of hormone receptor-positive breast cancer even if they lack access to costly multi-gene tests, as they report at the 4th IMPAKT Breast Cancer Conference. Because breast cancer is a biologically and clinically varied disease, doctors aim to choose appropriate treatments based on the characteristics of each patient's individual tumor. In the past, this has been done using pathology-based biomarkers; however these do not capture the full diversity of cancers. "In this context, ...

LAST 30 PRESS RELEASES:

Hear here: How loudness and acoustic cues help us judge where a speaker is facing

A unique method of rare-earth recycling can strengthen the raw material independence of Europe and America

Epilepsy self-management program shows promise to control seizures, improve mood and quality of life

Fat may play an important role in brain metabolism

New study finds no lasting impact of pandemic pet ownership on human well-being

New insights on genetic damage of some chemotherapies could guide future treatments with less harmful side effects

Gut microbes could protect us from toxic ‘forever chemicals’

Novel modelling links sea ice loss to Antarctic ice shelf calving events

Scientists can tell how fast you're aging from a single brain scan

U.S. uterine cancer incidence and mortality rates expected to significantly increase by 2050

Public take the lead in discovery of new exploding star

What are they vaping? Study reveals alarming surge in adolescent vaping of THC, CBD, and synthetic cannabinoids

ECMWF - delivering forecasts over 10 times faster and cutting energy usage by 1000

Brazilian neuroscientist reveals how viral infections transform the brain through microscopic detective work

Turning social fragmentation into action through discovering relatedness

Cheese may really be giving you nightmares, scientists find

Study reveals most common medical emergencies in schools

Breathable yet protective: Next-gen medical textiles with micro/nano networks

Frequency-engineered MXene supercapacitors enable efficient pulse charging in TENG–SC hybrid systems

Developed an AI-based classification system for facial pigmented lesions

Achieving 20% efficiency in halogen-free organic solar cells via isomeric additive-mediated sequential processing

New book Terraglossia reclaims language, Country and culture

The most effective diabetes drugs don't reach enough patients yet

Breast cancer risk in younger women may be influenced by hormone therapy

Strategies for staying smoke-free after rehab

Commentary questions the potential benefit of levothyroxine treatment of mild hypothyroidism during pregnancy

Study projects over 14 million preventable deaths by 2030 if USAID defunding continues

New study reveals 33% gap in transplant access for UK’s poorest children

Dysregulated epigenetic memory in early embryos offers new clues to the inheritance of polycystic ovary syndrome (PCOS)

IVF and IUI pregnancy rates remain stable across Europe, despite an increasing uptake of single embryo transfer

[Press-News.org] Study finds 'overmanagement' of benign breast disease